Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   OTU45_RS10780 Genome accession   NZ_CP113114
Coordinates   2092447..2093400 (-) Length   317 a.a.
NCBI ID   WP_000345101.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2087447..2098400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS10750 (OTU45_10750) - 2088208..2088831 (-) 624 WP_000932633.1 hypothetical protein -
  OTU45_RS10755 (OTU45_10755) jag 2088882..2089868 (-) 987 WP_000260009.1 RNA-binding cell elongation regulator Jag/EloR -
  OTU45_RS10760 (OTU45_10760) - 2089887..2090711 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  OTU45_RS10765 (OTU45_10765) rnpA 2090686..2091057 (-) 372 WP_000739246.1 ribonuclease P protein component -
  OTU45_RS10770 (OTU45_10770) - 2091074..2091205 (-) 132 WP_000768904.1 hypothetical protein -
  OTU45_RS10775 (OTU45_10775) - 2091206..2092396 (-) 1191 WP_000167766.1 acetate kinase -
  OTU45_RS10780 (OTU45_10780) comYH 2092447..2093400 (-) 954 WP_000345101.1 class I SAM-dependent methyltransferase Machinery gene
  OTU45_RS10785 (OTU45_10785) - 2093461..2094055 (-) 595 Protein_2108 class I SAM-dependent methyltransferase -
  OTU45_RS10790 (OTU45_10790) comGG/cglG 2094192..2094605 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  OTU45_RS10795 (OTU45_10795) comGF/cglF 2094583..2095044 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  OTU45_RS10800 (OTU45_10800) comGE/cglE 2095007..2095309 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  OTU45_RS10805 (OTU45_10805) comGD/cglD 2095272..2095676 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  OTU45_RS10810 (OTU45_10810) comGC/cglC 2095669..2095935 (-) 267 WP_050073122.1 competence type IV pilus major pilin ComGC Machinery gene
  OTU45_RS10815 (OTU45_10815) - 2095937..2096194 (-) 258 WP_000698513.1 hypothetical protein -
  OTU45_RS10820 (OTU45_10820) lytA 2096426..2097382 (-) 957 WP_054436120.1 N-acetylmuramoyl-L-alanine amidase LytA -
  OTU45_RS10825 (OTU45_10825) - 2097382..2097717 (-) 336 WP_001186204.1 phage holin -
  OTU45_RS10830 (OTU45_10830) - 2097721..2098020 (-) 300 WP_001811580.1 hypothetical protein -
  OTU45_RS10835 (OTU45_10835) - 2098030..2098380 (-) 351 WP_054368148.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35717.95 Da        Isoelectric Point: 4.2995

>NTDB_id=760370 OTU45_RS10780 WP_000345101.1 2092447..2093400(-) (comYH) [Streptococcus pneumoniae strain NP1]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=760370 OTU45_RS10780 WP_000345101.1 2092447..2093400(-) (comYH) [Streptococcus pneumoniae strain NP1]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAGACTGAGCTAGAACAGGTCAAAGACAACAATC
AGACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTACTTTTGGTGTTTATTGTGGAAGAGCTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATTTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGTGATGTGGTCATCAGCGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGTCAAGAACATACTTACACCCATCACTTGCTCA
TGGAACAAGGACTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTAATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536