Detailed information NTG0760317

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: OTU45_RS00500
• Genome accession: NZ_CP113114
• Coordinates: 92010..93359 (+)
• Length: 449 a.a.
• NCBI ID: WP_000801606.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP1
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 87010..98359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTU45_RS00480 (OTU45_00480)	blpU	87191..87421 (+)	231	WP_001093076.1	bacteriocin-like peptide BlpU	-
OTU45_RS00485 (OTU45_00485)	-	87424..87549 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
OTU45_RS00490 (OTU45_00490)	-	87986..89332 (+)	1347	WP_001826500.1	IS1380-like element ISSpn5 family transposase	-
OTU45_RS00495 (OTU45_00495)	comA	89844..91997 (+)	2154	WP_000668279.1	peptide cleavage/export ABC transporter ComA	Regulator
OTU45_RS00500 (OTU45_00500)	comB	92010..93359 (+)	1350	WP_000801606.1	competence pheromone export protein ComB	Regulator
OTU45_RS00505 (OTU45_00505)	purC	93529..94236 (+)	708	WP_000043305.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
OTU45_RS00510 (OTU45_00510)	-	94293..98018 (+)	3726	WP_267749646.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49642.51 Da
• Isoelectric Point: 5.3895

>NTDB_id=760317 OTU45_RS00500 WP_000801606.1 92010..93359(+) (comB) [Streptococcus pneumoniae strain NP1]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=760317 OTU45_RS00500 WP_000801606.1 92010..93359(+) (comB) [Streptococcus pneumoniae strain NP1]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGCTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAATCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTTCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
TCTACAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae TIGR4	98.886	100	0.989
comB	Streptococcus pneumoniae D39	98.664	100	0.987
comB	Streptococcus pneumoniae R6	98.664	100	0.987
comB	Streptococcus pneumoniae Rx1	98.664	100	0.987
comB	Streptococcus mitis SK321	94.878	100	0.949
comB	Streptococcus mitis NCTC 12261	94.432	100	0.944
comB	Streptococcus gordonii str. Challis substr. CH1	55.111	100	0.552