Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   PALA52_RS23375 Genome accession   NZ_CP110347
Coordinates   5066258..5067595 (+) Length   445 a.a.
NCBI ID   WP_024914651.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain PALA52     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5061258..5072595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PALA52_RS23350 (PALA52_04636) pgeF 5061401..5062129 (-) 729 WP_024914656.1 peptidoglycan editing factor PgeF -
  PALA52_RS23355 (PALA52_04637) rluD 5062126..5063088 (-) 963 WP_024914655.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  PALA52_RS23360 (PALA52_04638) - 5063234..5064259 (+) 1026 WP_024914654.1 outer membrane protein assembly factor BamD -
  PALA52_RS23365 (PALA52_04639) - 5064416..5064661 (+) 246 WP_024914653.1 PP0621 family protein -
  PALA52_RS23370 (PALA52_04640) pilS 5064651..5066243 (+) 1593 WP_024914652.1 two-component system sensor histidine kinase PilS Regulator
  PALA52_RS23375 (PALA52_04641) pilR 5066258..5067595 (+) 1338 WP_024914651.1 two-component system response regulator PilR Regulator
  PALA52_RS23380 (PALA52_04642) thiO 5067640..5068734 (-) 1095 WP_024914650.1 glycine oxidase ThiO -
  PALA52_RS23385 (PALA52_04643) - 5068869..5069378 (+) 510 WP_058141281.1 GspH/FimT family pseudopilin -
  PALA52_RS23390 (PALA52_04644) - 5069484..5069990 (+) 507 WP_003102598.1 GspH/FimT family pseudopilin -
  PALA52_RS23395 (PALA52_04645) pilV 5069981..5070538 (+) 558 WP_058141282.1 type 4a pilus minor pilin PilV Machinery gene
  PALA52_RS23400 (PALA52_04646) pilW 5070535..5071359 (+) 825 WP_058141283.1 type 4a pilus minor pilin PilW -
  PALA52_RS23405 (PALA52_04647) pilX 5071356..5071943 (+) 588 WP_003112826.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49768.07 Da        Isoelectric Point: 5.6424

>NTDB_id=754278 PALA52_RS23375 WP_024914651.1 5066258..5067595(+) (pilR) [Pseudomonas aeruginosa strain PALA52]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTDDAQEKLKSYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=754278 PALA52_RS23375 WP_024914651.1 5066258..5067595(+) (pilR) [Pseudomonas aeruginosa strain PALA52]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGCTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCATACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTACGGGAGCTGGTGGCGACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCCCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAACTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGCGGCGAGTCCGGCAGCGGCAAGGAGCTGGTAGCGCGCCTGATCCACGAACAGGGGCCACGCATAGAGCGGCCTTT
CGTCCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTCTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAGCTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTACGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGTGTGCCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGACGACGCACAGGAAAAACTGAAGAGCTACCG
TTTCCCCGGCAACGTCCGCGAGCTGGAGAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGATGACCAGATCCAGCCTC
ACGACCTGCGCCTTGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAGATCGACAACCTCGAGGAT
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACCTTCCGCTCTATGCGCTACCGCCTGAAAAAGCTCGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.551

100

0.996
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384