Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   UKS_RS07655 Genome accession   NZ_AP021887
Coordinates   1512346..1514241 (-) Length   631 a.a.
NCBI ID   WP_156012488.1    Uniprot ID   A0A6H3SFF3
Organism   Streptococcus sp. 116-D4     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1507346..1519241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS07630 (UKS_14720) - 1507483..1508448 (+) 966 WP_156012480.1 LacI family DNA-binding transcriptional regulator -
  UKS_RS07635 (UKS_14730) - 1508485..1509759 (-) 1275 WP_156012482.1 hydroxymethylglutaryl-CoA reductase, degradative -
  UKS_RS07640 (UKS_14740) - 1509759..1510931 (-) 1173 WP_173020478.1 hydroxymethylglutaryl-CoA synthase -
  UKS_RS07645 (UKS_14750) - 1511045..1511494 (-) 450 WP_049495291.1 threonine/serine exporter family protein -
  UKS_RS07650 (UKS_14760) - 1511496..1512254 (-) 759 WP_156012486.1 threonine/serine exporter family protein -
  UKS_RS07655 (UKS_14770) stkP 1512346..1514241 (-) 1896 WP_156012488.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  UKS_RS07660 (UKS_14780) - 1514238..1514978 (-) 741 WP_156012490.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  UKS_RS07665 (UKS_14790) rsmB 1514993..1516306 (-) 1314 WP_173020479.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  UKS_RS07670 (UKS_14800) fmt 1516299..1517234 (-) 936 WP_156012492.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 69220.71 Da        Isoelectric Point: 9.0075

>NTDB_id=75370 UKS_RS07655 WP_156012488.1 1512346..1514241(-) (stkP) [Streptococcus sp. 116-D4]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAIRIMGQILLAMRLAHTRGIVHRDLKPQNILLTSDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSCLSYNRRNEPKLVFDETTKADTKTLPKVPQSTLTSIPKTPVKEDKPQPQ
PPQTEKPVPSVKPIKRRRIKARYPILFATFLLVVASLVWILYRTPATIAIPKVAGQTVAEAKEALKKANFEVGEEKSEAS
DKVEEGRVIRTDPDAGTTRKEGTKINLIVSSGPQSFQLGNYIGRKSSDVVAELKGKKVPENLIKIEEEESNEIEAGTIMK
QSLPEGTTYDLSKATQIVLTVAKKGNSISMPSYIGSSREFTVNNLTQIYEVKKANIEVVEVSTAPEGTAEGTVIEQSPKA
GEKVDLSATRVKLSIYKAKQTHSSSTSSSSSSSSSSSSRKTNEQEDAESTPTQGSSQGNSQRGDTSRENPQ

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=75370 UKS_RS07655 WP_156012488.1 1512346..1514241(-) (stkP) [Streptococcus sp. 116-D4]
ATGATCCAAATCGGCAAAATTTTTGCCGGGCGGTATCGGATTATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTCTA
TTTAGCCAAGGATTTGATTTTAGACGGTGAAGAAGTGGCAGTCAAGGTTCTGCGAACCAACTACCAGACAGATCCTATTG
CAGTGGCGCGTTTCCAGCGGGAAGCAAGAGCCATGGCAGATCTGGACCATCCTCATATCGTTCGGATTACAGATATCGGT
GAAGAAGAGGGACAACAGTATCTTGCAATGGAGTATGTTGCTGGATTAGACCTCAAACGCTATATCAAGGAACATCATCC
TCTTTCGAATGAAGAAGCGATTCGAATCATGGGACAAATCCTCTTGGCAATGCGCTTAGCTCATACTCGAGGGATTGTTC
ACAGGGATTTGAAACCTCAAAATATTCTCTTGACATCAGATGGGACGGCCAAGGTCACAGACTTTGGGATCGCGGTAGCC
TTTGCAGAGACGAGTCTGACTCAGACCAACTCAATGCTAGGTTCAGTTCATTATTTGTCACCAGAGCAGGCGCGTGGTTC
TAAAGCGACTGTACAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTACGATG
GGGATAGTGCGGTGACCATCGCCCTCCAACATTTTCAGAAGCCATTGCCATCGGTTATTGCTGAAAATCCATCTGTGCCT
CAGGCTTTAGAAAATGTTGTTATCAAGGCAACTGCCAAGAAATTGACAGACCGCTACAAATCAGTCGCGGAAATGTATGT
GGATTTGTCTAGTTGTTTGTCTTATAATCGTCGTAATGAACCAAAGCTAGTCTTTGACGAAACGACTAAGGCGGACACTA
AGACTCTTCCAAAAGTTCCACAAAGTACCTTGACTTCTATTCCTAAAACTCCGGTAAAAGAGGACAAGCCTCAACCTCAG
CCTCCTCAGACAGAAAAACCGGTACCTAGTGTAAAGCCAATCAAGCGGCGTCGTATAAAAGCACGTTATCCAATTTTATT
TGCGACCTTCTTGTTGGTTGTGGCATCTTTGGTATGGATTTTATATAGAACGCCCGCTACCATTGCCATTCCAAAGGTGG
CAGGTCAGACGGTTGCAGAGGCCAAAGAAGCTCTTAAAAAAGCCAATTTTGAGGTTGGTGAAGAAAAATCAGAGGCTAGT
GATAAGGTTGAAGAAGGTCGGGTTATTCGTACCGATCCTGACGCAGGTACGACACGCAAAGAAGGAACAAAAATTAATTT
GATTGTGTCTTCTGGTCCGCAATCTTTCCAACTTGGAAATTATATTGGAAGAAAATCCAGTGATGTAGTGGCAGAATTGA
AAGGCAAGAAGGTTCCAGAAAATCTGATTAAGATTGAAGAAGAAGAATCCAACGAAATCGAAGCCGGTACAATCATGAAA
CAAAGTTTACCGGAGGGAACAACCTACGATCTTAGCAAGGCAACTCAAATAGTTCTGACTGTTGCTAAAAAAGGAAATTC
TATTTCAATGCCAAGTTATATTGGTTCTAGCCGAGAATTTACAGTCAATAATCTTACACAGATATATGAAGTTAAAAAAG
CTAATATCGAAGTTGTAGAAGTGTCTACAGCTCCTGAAGGAACAGCTGAGGGGACTGTCATAGAGCAAAGTCCAAAAGCA
GGTGAAAAAGTAGATTTGAGCGCAACTCGTGTTAAACTTTCTATATATAAAGCGAAGCAAACTCATTCTTCTTCAACTTC
ATCCTCCTCCTCTTCGTCGTCCTCTAGCTCTTCTCGGAAAACTAATGAACAAGAGGATGCAGAATCCACTCCCACACAGG
GAAGCTCGCAAGGCAATTCACAACGAGGAGATACTTCCCGAGAAAATCCACAGTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(369-430)

PASTA domain (PASTA)

(509-577)

PASTA domain (PASTA)

(439-503)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6H3SFF3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

79.21

92.235

0.731
  stkP Streptococcus pneumoniae D39

78.866

92.235

0.727
  stkP Streptococcus pneumoniae R6

78.866

92.235

0.727
  stkP Streptococcus pneumoniae Rx1

78.694

92.235

0.726
  stkP/pknB Streptococcus salivarius strain HSISS4

54.655

91.918

0.502
  pknB Streptococcus mutans UA159

54.231

91.759

0.498

Multiple sequence alignment