Detailed information NTG0075354

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: UKS_RS04375
• Genome accession: NZ_AP021887
• Coordinates: 847576..849816 (+)
• Length: 746 a.a.
• NCBI ID: WP_156011949.1
• Uniprot ID: -
• Organism: Streptococcus sp. 116-D4
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 842576..854816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UKS_RS04345 (UKS_08110)	-	843079..843636 (+)	558	WP_049495610.1	GrpB family protein	-
UKS_RS04350 (UKS_08120)	-	843682..843897 (+)	216	WP_001232084.1	YozE family protein	-
UKS_RS04355 (UKS_08130)	-	843982..844956 (+)	975	WP_156011945.1	PhoH family protein	-
UKS_RS04360 (UKS_08140)	ald	845020..846132 (-)	1113	WP_156011946.1	alanine dehydrogenase	-
UKS_RS04365 (UKS_08150)	-	846306..846875 (+)	570	WP_156011947.1	GNAT family N-acetyltransferase	-
UKS_RS04370 (UKS_08160)	comEA/celA/cilE	846942..847592 (+)	651	WP_156011948.1	helix-hairpin-helix domain-containing protein	Machinery gene
UKS_RS04375 (UKS_08170)	comEC/celB	847576..849816 (+)	2241	WP_156011949.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
UKS_RS04380 (UKS_08180)	-	849947..850195 (+)	249	WP_332066893.1	hypothetical protein	-
UKS_RS04385 (UKS_08190)	-	850228..850815 (+)	588	WP_156011951.1	ABC transporter ATP-binding protein	-
UKS_RS04390 (UKS_08200)	-	850819..852003 (+)	1185	WP_156011952.1	hypothetical protein	-
UKS_RS04395 (UKS_08210)	-	852103..853359 (-)	1257	WP_173020495.1	ISL3 family transposase	-
UKS_RS04400 (UKS_08220)	infC	853732..854262 (+)	531	WP_000848184.1	translation initiation factor IF-3	-
UKS_RS04405 (UKS_08230)	rpmI	854295..854495 (+)	201	WP_049496086.1	50S ribosomal protein L35	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84507.81 Da
• Isoelectric Point: 9.3783

>NTDB_id=75354 UKS_RS04375 WP_156011949.1 847576..849816(+) (comEC/celB) [Streptococcus sp. 116-D4]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSTSKVLAICGIFGFWFLFQTWQQTQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSDGRIFQVYYKLQSEEEKETFQALTALHDLELEGKLSEPEGRRNFGGFDYQSY
LKTQGIYQTLNIKRIQSLQKAGSWDIGENLSSLRRKAVVWIKTKFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWMTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGFKGLDNFALTVLVLFIA
MPNFFLTAGGILSCAYAFILTMTSKEGEGLKAVTRESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNVIFEWLEGIIRLVSQVASRPLVFGQPTTWLLILLLVSLALLYDMRKNIKRLAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKVESDKKIEKWQEKATTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKEFVAELEASQTKVRSVTAGENLPIFGSQLEVLSPGKIGEVGSNDSLVLYGKL
LDKHFLFTENLEEKGEKDLLKQYPDLEVDVLKAGQHGSKKSSSSAFLEQLKPEITLISVGKSNRTKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGWKSWKIESIR

Nucleotide

• Length: 2241 bp

>NTDB_id=75354 UKS_RS04375 WP_156011949.1 847576..849816(+) (comEC/celB) [Streptococcus sp. 116-D4]
ATGTTGCAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTTTGGCTTTACTACGCCATTTT
TTCAGCATCCTATCTTGCTTTATTGGGCTTTGTTTTTCTGCTAGTTTGTCTCTTTATTCAATTTCCTTGGAAATCTACTA
GCAAAGTTCTAGCAATTTGTGGAATCTTTGGATTTTGGTTTCTATTTCAAACTTGGCAGCAGACACAAGCTAGTCAGAAC
CTAGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGACACTATTAAGGTCAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAACCTTTCAAGCCTTAACAGCTC
TTCATGATTTGGAACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGAGGAGAAATTTTGGTGGCTTTGACTACCAATCCTAT
CTGAAAACTCAGGGAATTTACCAGACTCTCAATATCAAAAGAATCCAGTCGCTTCAAAAGGCTGGCAGTTGGGATATAGG
TGAAAACCTATCCAGTTTACGTCGAAAGGCTGTAGTTTGGATTAAGACAAAGTTTCCAGATCCTATGCGCAATTACATGA
CGGGGCTTCTATTAGGACATCTCGACACCGACTTCGAGGAAATGAATGAACTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCTTGTCGGGTATGCAGGTAGGCTTTTTCATGGATGGCTTTAAGAAACTTCTTTTGCGACTGGGGTTGACTCAAGA
AAAGTTGAAATGGATGACTTATCCCTTTTCTCTTATTTATGCAGGTCTGACAGGATTTTCAGCTTCGGTCATTCGCAGTC
TCTTGCAAAAGTTACTGGCTCAACATGGTTTTAAGGGCTTGGATAATTTTGCCTTGACAGTCCTTGTCCTCTTTATCGCC
ATGCCCAACTTTTTCCTGACGGCGGGAGGTATTTTGTCTTGTGCCTACGCTTTTATCTTGACCATGACCAGCAAAGAAGG
AGAGGGGCTTAAGGCTGTGACCAGAGAAAGTCTGGTTATTTCTTTGGGCATATTACCCATCCTATCCTTCTATTTTGCAG
AATTTCAACCTTGGTCCATCCTCTTGACCTTTGTCTTTTCCTTTCTATTTGACTTAGTCTTCTTACCGCTCTTGTCCATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAACTGAATGTTATCTTTGAATGGTTGGAAGGCATTATTCGCTTGGT
ATCACAGGTGGCAAGTAGACCCCTGGTCTTTGGTCAACCCACCACATGGCTTTTGATTCTTCTCTTAGTTTCATTAGCCT
TGCTCTATGATATGAGAAAAAATATCAAAAGACTAGCAGGATTTAGTCTCTTTATCGTGGGGCTCTTTTTCTTGACCAAG
CATCCACTGGAAAATGAAATTACCATGCTGGATGTGGGGCAAGGCGAAAGTATTTTCCTAAGGGATGTAACTGGTAAGAC
CATTCTCATAGATGTCGGTGGCAAGGTAGAATCTGATAAGAAAATCGAAAAATGGCAAGAAAAAGCGACAACCAGTAATG
CGCAGAGAACCTTGATTCCCTATCTTAAAAGTCGCGGAGTAGCCAAGATTGACCAGCTAATTTTGACCAACACAGACAAG
GAACATGTTGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTGGTATCAAAAGGAAGTTTGAAACA
GAAGGAATTTGTGGCGGAACTAGAAGCAAGCCAAACCAAGGTACGCAGTGTGACAGCAGGGGAGAATTTACCGATTTTTG
GCAGTCAGTTAGAAGTCCTATCTCCAGGGAAGATTGGAGAAGTTGGTTCCAATGATTCCTTGGTTCTTTATGGGAAACTC
TTGGATAAGCACTTTCTCTTCACGGAAAATTTGGAGGAGAAAGGAGAGAAGGATCTTCTAAAGCAATATCCTGACCTAGA
GGTGGATGTTTTGAAAGCTGGCCAACATGGCTCTAAAAAATCATCAAGTTCGGCCTTTTTAGAACAGCTTAAACCGGAGA
TCACTCTCATCTCAGTTGGAAAGAGCAATCGAACGAAACTCCCCCATCAGGAAACCCTGACCCGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGATTTAAAGGTTGGAAGAGTTGGAAGATCGAAAGTATTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-611)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	92.091	100	0.921
comEC/celB	Streptococcus mitis NCTC 12261	90.201	99.866	0.901
comEC/celB	Streptococcus pneumoniae TIGR4	90.08	100	0.901
comEC/celB	Streptococcus pneumoniae D39	89.544	100	0.895
comEC/celB	Streptococcus pneumoniae Rx1	89.544	100	0.895
comEC/celB	Streptococcus pneumoniae R6	89.544	100	0.895
comEC	Lactococcus lactis subsp. cremoris KW2	44.669	99.33	0.444