Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   OL235_RS01275 Genome accession   NZ_CP110237
Coordinates   258194..259462 (-) Length   422 a.a.
NCBI ID   WP_275469365.1    Uniprot ID   A0AAF0CVD9
Organism   Vagococcus intermedius strain STAA25     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 253194..264462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OL235_RS01255 (OL235_01255) walK 253368..255191 (+) 1824 WP_275469362.1 cell wall metabolism sensor histidine kinase WalK -
  OL235_RS01260 (OL235_01260) - 255188..256486 (+) 1299 WP_275469363.1 YycH family regulatory protein -
  OL235_RS01265 (OL235_01265) - 256486..257304 (+) 819 WP_275469364.1 two-component system regulatory protein YycI -
  OL235_RS01270 (OL235_01270) - 257355..258161 (+) 807 WP_275470089.1 MBL fold metallo-hydrolase -
  OL235_RS01275 (OL235_01275) htrA 258194..259462 (-) 1269 WP_275469365.1 S1C family serine protease Regulator
  OL235_RS01280 (OL235_01280) rlmH 259846..260325 (+) 480 WP_275470090.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  OL235_RS01285 (OL235_01285) - 260898..263990 (+) 3093 WP_275469366.1 hypothetical protein -
  OL235_RS01290 (OL235_01290) - 263980..264336 (+) 357 WP_275469367.1 LPXTG cell wall anchor domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45391.10 Da        Isoelectric Point: 4.8846

>NTDB_id=753315 OL235_RS01275 WP_275469365.1 258194..259462(-) (htrA) [Vagococcus intermedius strain STAA25]
MKKDVTPHTKQTGERKRFLTGLLGGIIGGLVTVGVAFTFFNPMPSNDKPVSSSKEDKQETNVSSIKYDVDSNVSKAVENV
QEAVVSVVNLQKKEQLNDFSRFFGAKENEESHTTNDELEASSEGSGVIYRKDKDHSYIVTNNHVVDGSDALQVLLNDGTK
IDAKLVGKDSYTDLAVLEVPSEKVKKAAEFGDSDKLKVGEPAIAIGSPLGSVYANSATLGIISAKDRKITNENESGQPVN
INALQTDAAINPGNSGGPLINIAGQVIGINSIKIAQATSGVSAEGMGFSIPSNDVVSIISQLEKDGEVNRPMLGITMSDL
AMISKEQQENILKLPNDVKNGVIVRSLQFASPAEKAGLKQYDVIVAIDGKEIESGTDLQSILYKKKVGETVELTYYREKE
KKTTTVELTLDQASALKQQQKE

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=753315 OL235_RS01275 WP_275469365.1 258194..259462(-) (htrA) [Vagococcus intermedius strain STAA25]
ATGAAAAAAGATGTCACACCACATACAAAACAAACTGGCGAACGAAAACGATTTTTAACAGGATTGCTTGGAGGGATTAT
CGGCGGATTAGTGACCGTAGGCGTTGCCTTTACTTTTTTTAATCCCATGCCTTCAAACGACAAGCCAGTTAGCTCTTCAA
AAGAAGATAAACAAGAAACAAATGTCAGTTCTATTAAATATGACGTAGACTCTAACGTCTCAAAAGCGGTTGAAAATGTC
CAGGAAGCGGTTGTCTCTGTCGTGAATCTTCAGAAAAAAGAACAATTAAATGATTTTAGCCGTTTCTTTGGAGCGAAAGA
AAATGAAGAGTCACATACAACGAATGACGAATTAGAAGCGAGTAGTGAAGGGAGTGGTGTTATTTACCGTAAAGATAAGG
ACCACTCTTATATTGTGACAAATAACCACGTAGTAGATGGTTCTGATGCCTTGCAAGTTTTATTAAATGATGGGACTAAG
ATTGATGCTAAACTAGTTGGGAAAGATAGCTATACTGACTTAGCCGTCTTAGAAGTTCCAAGTGAGAAAGTCAAAAAAGC
AGCTGAGTTTGGTGACTCTGATAAATTAAAAGTAGGAGAGCCAGCGATTGCTATTGGTTCCCCCTTAGGATCAGTTTATG
CTAACAGTGCCACTTTAGGAATTATCTCTGCTAAAGATCGTAAGATTACAAATGAAAATGAAAGCGGCCAACCCGTCAAC
ATCAATGCTTTACAAACAGATGCTGCCATTAATCCTGGTAATTCTGGTGGCCCACTGATTAATATCGCCGGGCAAGTCAT
TGGTATCAACTCTATTAAGATTGCTCAAGCAACTAGCGGCGTTTCAGCTGAGGGAATGGGCTTTTCAATTCCAAGTAATG
ATGTTGTTTCAATTATTAGCCAATTAGAAAAAGATGGTGAAGTGAACCGACCAATGTTAGGGATTACAATGAGTGATTTG
GCAATGATCAGTAAAGAACAACAAGAAAATATCTTAAAACTTCCTAACGACGTTAAAAACGGAGTTATTGTACGTAGCTT
ACAATTTGCCTCTCCTGCTGAAAAAGCTGGTTTAAAACAATATGATGTCATTGTGGCAATCGATGGTAAAGAAATCGAAA
GTGGGACTGACTTACAATCTATCTTGTACAAGAAAAAAGTTGGAGAAACAGTTGAGCTTACTTACTACCGCGAAAAAGAA
AAGAAAACTACAACCGTTGAATTAACTTTAGATCAAGCTTCGGCCCTTAAACAACAACAAAAAGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(311-408)

Trypsin-like peptidase domain (Trypsin_2)

(124-269)

Peptidase family M50 (Peptidase_M50)

(15-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

52.152

93.602

0.488
  htrA Streptococcus gordonii str. Challis substr. CH1

47.837

93.128

0.445
  htrA Streptococcus pneumoniae Rx1

49.856

82.227

0.41
  htrA Streptococcus pneumoniae D39

49.856

82.227

0.41
  htrA Streptococcus pneumoniae R6

49.856

82.227

0.41
  htrA Streptococcus pneumoniae TIGR4

49.856

82.227

0.41
  htrA Streptococcus mitis NCTC 12261

49.568

82.227

0.408