Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   OLM01_RS12860 Genome accession   NZ_CP110041
Coordinates   2612187..2613485 (+) Length   432 a.a.
NCBI ID   WP_010709051.1    Uniprot ID   -
Organism   Enterococcus faecalis strain BE43     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2607187..2618485
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OLM01_RS12850 (OLM01_12850) - 2608160..2610724 (-) 2565 Protein_2512 EF3023 family LPXTG-anchored polysaccharide lyase -
  OLM01_RS12855 (OLM01_12855) rlmH 2611307..2611786 (-) 480 WP_002355021.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  OLM01_RS12860 (OLM01_12860) htrA 2612187..2613485 (+) 1299 WP_010709051.1 S1C family serine protease Regulator
  OLM01_RS12865 (OLM01_12865) ytpR 2613532..2614152 (-) 621 WP_002361057.1 YtpR family tRNA-binding protein -
  OLM01_RS12870 (OLM01_12870) - 2614363..2614818 (-) 456 WP_002385249.1 universal stress protein -
  OLM01_RS12875 (OLM01_12875) - 2614966..2615280 (-) 315 WP_002355015.1 thioredoxin family protein -
  OLM01_RS12880 (OLM01_12880) pepA 2615292..2616368 (-) 1077 WP_002389404.1 glutamyl aminopeptidase -
  OLM01_RS12885 (OLM01_12885) - 2616675..2617016 (+) 342 WP_002355012.1 PepSY domain-containing protein -
  OLM01_RS12890 (OLM01_12890) - 2617244..2618203 (-) 960 WP_002389223.1 IS30-like element IS1062 family transposase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44830.97 Da        Isoelectric Point: 5.1142

>NTDB_id=751721 OLM01_RS12860 WP_010709051.1 2612187..2613485(+) (htrA) [Enterococcus faecalis strain BE43]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIQGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=751721 OLM01_RS12860 WP_010709051.1 2612187..2613485(+) (htrA) [Enterococcus faecalis strain BE43]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACATCCACTAATCACGGCGACACAAAAGTCAGCAATGTAAGTTACAATGTGTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGAAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCAATTG
GTTCCCCTCTAGGCTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTCAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACTATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(9-416)

PDZ domain (PDZ_2)

(319-416)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.415

94.907

0.507
  htrA Streptococcus mutans UA159

58.63

84.491

0.495
  htrA Streptococcus mitis NCTC 12261

55.405

85.648

0.475
  htrA Streptococcus pneumoniae TIGR4

56.091

81.713

0.458
  htrA Streptococcus pneumoniae Rx1

56.091

81.713

0.458
  htrA Streptococcus pneumoniae D39

56.091

81.713

0.458
  htrA Streptococcus pneumoniae R6

56.091

81.713

0.458