Detailed information NTG0740445

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: OFW50_RS10960
• Genome accession: NZ_CP107523
• Coordinates: 2277259..2279451 (-)
• Length: 730 a.a.
• NCBI ID: WP_263932513.1
• Uniprot ID: -
• Organism: Lacticaseibacillus chiayiensis strain AACE 3
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2272259..2284451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OFW50_RS10940 (OFW50_10940)	-	2272456..2272659 (+)	204	WP_129302258.1	hypothetical protein	-
OFW50_RS10945 (OFW50_10945)	-	2273120..2274094 (+)	975	Protein_2125	aldo/keto reductase	-
OFW50_RS10950 (OFW50_10950)	-	2274397..2275752 (-)	1356	WP_129302257.1	threonine/serine ThrE exporter family protein	-
OFW50_RS10955 (OFW50_10955)	-	2275867..2277246 (-)	1380	WP_129302256.1	bacteriocin secretion accessory protein	-
OFW50_RS10960 (OFW50_10960)	comA	2277259..2279451 (-)	2193	WP_263932513.1	peptide cleavage/export ABC transporter	Regulator
OFW50_RS10965 (OFW50_10965)	-	2279760..2279906 (-)	147	WP_158280525.1	bacteriocin-like peptide, LSEI_2386 family	-
OFW50_RS10970 (OFW50_10970)	-	2280075..2281376 (+)	1302	WP_213224079.1	GHKL domain-containing protein	-
OFW50_RS10975 (OFW50_10975)	-	2281378..2282184 (+)	807	WP_129302254.1	response regulator transcription factor	-
OFW50_RS10980 (OFW50_10980)	-	2282367..2282651 (-)	285	WP_129302253.1	hypothetical protein	-
OFW50_RS10985 (OFW50_10985)	-	2283590..2283796 (-)	207	WP_129302252.1	TmhB bacteriocin enhancer peptide	-
OFW50_RS10990 (OFW50_10990)	-	2283817..2284056 (-)	240	WP_129302251.1	Blp family class II bacteriocin	-
OFW50_RS10995 (OFW50_10995)	-	2284067..2284432 (-)	366	WP_158280576.1	thioredoxin family protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81847.39 Da
• Isoelectric Point: 7.8981

>NTDB_id=740445 OFW50_RS10960 WP_263932513.1 2277259..2279451(-) (comA) [Lacticaseibacillus chiayiensis strain AACE 3]
MFKYKFKLGQATYYKRHYTPQVDERDCGVAALNMLLKFHRSDYSLAHLRQLAKTDQEGTTALGIVRAAQELHFETKAVKA
DMTLFDLNDAPYPILVHVLKRGELLHYYVVFKATKDYILIGDPDPSVAMTWLSKDEFAKEWSGVAIFIAPEPQYQPRKED
KDSLFAFVPLLARQKVIIANIIVAALLLTVISIVGSYFLQSIIDTYIPSAMRTTLGMIASGLILAYILQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFATRRTGEIVSRFSDANKIIDALANTIMTLFLDVWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLSYFTNPLESIINLQPKLQMAKVANKRLNEVYLVESEFKE
QRHLTDRRLIDGAINVHDVSFKYGFGQDILKHVHLEVPANAKYTIVGMSGSGKSTLAKLLVGFYPIDTGKGKITFNGAQI
NDVALTTLRQYIEYVPQEPFIFSGSVMENLTLGSRADLTQAQLEDACAVAEIATDIMNLPQMWQTKLTESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERRIVDRLLAMEDRTIIFVAHRLTIAAKTEQIVVMNHGEIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=740445 OFW50_RS10960 WP_263932513.1 2277259..2279451(-) (comA) [Lacticaseibacillus chiayiensis strain AACE 3]
ATGTTCAAATACAAATTCAAACTAGGCCAAGCAACATACTACAAACGTCATTACACGCCTCAGGTGGATGAGCGTGATTG
CGGCGTTGCGGCGCTTAATATGTTACTGAAGTTTCATAGGTCCGACTATTCCCTTGCGCATTTACGGCAATTAGCCAAGA
CGGATCAGGAAGGAACAACAGCATTAGGCATTGTTCGGGCCGCCCAGGAACTTCATTTTGAAACCAAGGCAGTTAAGGCG
GATATGACGTTGTTTGATTTAAATGATGCGCCATATCCGATCTTGGTGCATGTTTTGAAGCGTGGCGAGTTGTTGCATTA
TTATGTCGTGTTTAAGGCGACGAAGGATTATATCTTAATCGGTGATCCTGACCCTTCAGTCGCAATGACCTGGCTTTCAA
AAGATGAGTTTGCCAAGGAGTGGTCGGGGGTGGCTATCTTTATTGCTCCTGAACCACAATATCAACCGCGCAAAGAGGAC
AAAGACAGCTTGTTTGCCTTCGTGCCGTTACTTGCGCGGCAAAAAGTGATCATTGCCAATATTATTGTTGCGGCTTTGTT
GCTCACGGTGATTAGTATTGTCGGGTCGTATTTTTTGCAATCGATTATTGATACCTATATTCCCAGTGCCATGCGGACAA
CCTTGGGCATGATCGCCAGTGGGCTGATTCTCGCTTACATTCTTCAATCTGTTTTGACGTATGGTCAGAACTTTTTGATG
GCGGTTTTAGGCCAGCGGTTGTCGATTGACGTTATTTTGGGTTACGTTCGGCATCTGTATGAATTACCCATGTCTTTTTT
TGCAACACGCCGGACAGGGGAGATTGTGTCGCGGTTTTCGGATGCCAATAAAATTATCGATGCCTTGGCGAATACGATCA
TGACCCTGTTTCTTGACGTTTGGATCGTGCTTATTTTAGGCATTGTTCTAGGCATTCAAAATACCACGTTGTTCCTGGTG
TCCTTAATTGCGGTGCCTTGTTACTTGGTGATTGTTTTCGCGTTTCAACGTCCTTTCAATCGGCTGAATCAAGAGACAAT
GGAAAGCAATGCCATTTTGAGTTCATCAATTATTGAGGATCTAAACGGTATTGAGACCATTAAGTCGCTGACAGGCGAAA
AAGTCAGTTATGAGCGGGTTGACCGTGAATTCGTCACGTATTTAAAAAAGTCATTCAATTACACGAAAGCCGACCAGCTT
CAACAAGCTATCAAAGGGTTGCTGAAACTCGTCTTGAATGTGGTGGTGTTGTGGATTGGGGCGAGTCTGGTGATGGCGAA
CAAGATGAGCTTGGGGCAGATGCTGACGTTCAATGCCTTGCTGTCATATTTCACCAATCCGTTAGAAAGTATCATTAACT
TGCAACCTAAATTACAAATGGCCAAGGTGGCGAATAAGCGGCTGAATGAGGTTTATTTGGTTGAATCTGAGTTTAAAGAA
CAGCGCCATCTGACCGATCGCCGCCTGATCGATGGTGCCATCAACGTGCATGATGTTTCCTTTAAATACGGGTTTGGTCA
GGATATTTTGAAGCATGTCCATCTTGAAGTGCCCGCAAACGCTAAATACACGATTGTTGGGATGAGTGGGTCAGGCAAGT
CAACGTTGGCCAAATTATTAGTCGGCTTTTACCCGATCGATACAGGCAAGGGAAAAATCACCTTTAATGGCGCGCAGATT
AATGATGTGGCGCTCACGACGCTGCGGCAATATATCGAGTATGTGCCGCAAGAGCCGTTTATTTTTTCCGGATCGGTGAT
GGAAAACTTAACGTTAGGCAGTCGTGCCGATTTGACGCAGGCGCAACTTGAAGACGCATGTGCCGTTGCGGAGATTGCCA
CGGATATTATGAATTTGCCGCAAATGTGGCAGACCAAGCTCACGGAAAGCGGGAGCATTTTATCAGGCGGTCAGAAGCAG
CGCTTGGCGATTGCACGGGCGTTGTTATCGCCGGCCAAAGTGCTGATTTTTGATGAGTCGACTAGCAGTCTGGATACCAT
CACGGAGCGGCGGATTGTGGATCGGTTGTTGGCGATGGAAGATCGAACCATTATTTTTGTTGCCCATCGACTCACAATTG
CGGCCAAAACCGAACAGATTGTCGTCATGAATCATGGCGAAATTGTCGAGCAAGGCAATCACGCAGAACTGCTGGCCAAA
CAAGGCTATTATGCGCGGCTGGTGAGTGAATGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.182	97.945	0.57
comA	Streptococcus pneumoniae Rx1	58.182	97.945	0.57
comA	Streptococcus pneumoniae D39	58.182	97.945	0.57
comA	Streptococcus pneumoniae R6	58.182	97.945	0.57
comA	Streptococcus mitis SK321	58.042	97.945	0.568
comA	Streptococcus pneumoniae TIGR4	57.762	97.945	0.566
comA	Streptococcus gordonii str. Challis substr. CH1	56.485	98.219	0.555
comA/nlmT	Streptococcus mutans UA159	54.432	98.904	0.538