Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   QA712_RS05780 Genome accession   NZ_CP121539
Coordinates   1054617..1056494 (-) Length   625 a.a.
NCBI ID   WP_372757882.1    Uniprot ID   -
Organism   Lactococcus lactis strain MA5     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1049617..1061494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA712_RS05750 (QA712_05750) - 1050026..1050706 (-) 681 WP_012898438.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  QA712_RS05755 (QA712_05755) macP 1050738..1051016 (-) 279 WP_003130796.1 cell wall synthase accessory phosphoprotein MacP -
  QA712_RS05760 (QA712_05760) - 1051009..1051593 (-) 585 WP_372757880.1 NUDIX hydrolase -
  QA712_RS05765 (QA712_05765) glmU 1051698..1053074 (-) 1377 WP_332529369.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  QA712_RS05770 (QA712_05770) proC 1053302..1054090 (+) 789 WP_012898440.1 pyrroline-5-carboxylate reductase -
  QA712_RS05775 (QA712_05775) rpsO 1054168..1054437 (-) 270 WP_015427039.1 30S ribosomal protein S15 -
  QA712_RS05780 (QA712_05780) stkP/pknB 1054617..1056494 (-) 1878 WP_372757882.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QA712_RS05785 (QA712_05785) - 1056494..1057270 (-) 777 WP_058203446.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QA712_RS05790 (QA712_05790) rsmB 1057350..1058624 (-) 1275 WP_332529367.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  QA712_RS05795 (QA712_05795) - 1058823..1059329 (-) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  QA712_RS05800 (QA712_05800) - 1059350..1059538 (-) 189 WP_012898445.1 DUF2273 domain-containing protein -
  QA712_RS05805 (QA712_05805) amaP 1059549..1060109 (-) 561 WP_047206829.1 alkaline shock response membrane anchor protein AmaP -
  QA712_RS05810 (QA712_05810) - 1060137..1060379 (-) 243 WP_003131476.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 67722.77 Da        Isoelectric Point: 4.7044

>NTDB_id=737295 QA712_RS05780 WP_372757882.1 1054617..1056494(-) (stkP/pknB) [Lactococcus lactis strain MA5]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMNDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVGNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKVPNVTNSTLSQAEIKIKAANLKVGTVHKQQSSTI
DEGKVIKTDPDKGSTVRSNSSVDIYISTGNENVIKMKDFIGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPNVGT
SVDPTQEIVVTYSVYTAPSSSSTTSESTTTPETSSSSSSSTTTQSSPENANSSSTKESSTTSSSS

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=737295 QA712_RS05780 WP_372757882.1 1054617..1056494(-) (stkP/pknB) [Lactococcus lactis strain MA5]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGCGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAGTTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCGCATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAGCTTTTAACAGGTCAAATCCCATTTGATG
GAGATTCTGCAGTTGCTATTGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATCAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAA
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGGAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGGTACCCAATGTGACAAATTCCA
CACTTAGTCAAGCTGAAATTAAAATTAAAGCTGCAAACCTTAAAGTGGGGACAGTTCATAAACAGCAAAGTTCAACAATT
GATGAAGGAAAGGTTATTAAAACTGATCCAGATAAAGGGTCAACCGTAAGATCCAACAGTTCAGTCGATATTTATATTTC
CACAGGAAATGAAAATGTCATTAAAATGAAGGACTTTATCGGTGAAAAGATTGATGAGGCGATGGCAACCTTACTTAAGG
ATTATGGCATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGCAGTGAAAAAATTACCTTTGAAGTTTCAAGCGGTAAACAAGTTGA
AGTCCCGGATTATAAACCGAACGGCCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACAAATCAACAAGCTGATGGTTATGTTTACTCAGTGTATCCAAATGTAGGAACA
TCTGTTGATCCAACTCAAGAAATTGTAGTTACTTACAGCGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAGTC
AACAACGACCCCTGAAACTTCGTCAAGCAGCTCAAGCTCTACAACAACTCAGTCATCACCAGAGAATGCTAATAGTAGTA
GTACTAAAGAATCTTCAACAACGTCATCAAGTAGTTGA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(434-501)

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(506-573)

Protein kinase domain (Pkinase)

(12-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

47.36

100

0.474
  pknB Streptococcus mutans UA159

49.265

87.04

0.429
  stkP Streptococcus pneumoniae TIGR4

47.233

80.96

0.382
  stkP Streptococcus pneumoniae D39

47.036

80.96

0.381
  stkP Streptococcus pneumoniae R6

47.036

80.96

0.381
  stkP Streptococcus pneumoniae Rx1

46.838

80.96

0.379