Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FNL60_RS03385 Genome accession   NZ_AP019720
Coordinates   618943..619650 (+) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus mutans strain NBRC 13955     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 613943..624650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL60_RS03355 (SM3g_05970) - 614433..614621 (+) 189 WP_002279970.1 DNA-directed RNA polymerase subunit beta -
  FNL60_RS03360 (SM3g_05980) endA 614663..615544 (+) 882 WP_002262935.1 DNA/RNA non-specific endonuclease Machinery gene
  FNL60_RS03365 (SM3g_05990) - 615612..616262 (-) 651 WP_002279971.1 amino acid ABC transporter permease -
  FNL60_RS03370 (SM3g_06000) - 616277..616981 (-) 705 WP_002264823.1 amino acid ABC transporter permease -
  FNL60_RS03375 (SM3g_06010) - 616999..617811 (-) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  FNL60_RS03380 (SM3g_06020) - 617808..618590 (-) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  FNL60_RS03385 (SM3g_06030) vicR 618943..619650 (+) 708 WP_002262930.1 response regulator YycF Regulator
  FNL60_RS03390 (SM3g_06040) vicK 619643..620995 (+) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FNL60_RS03395 (SM3g_06050) vicX 620992..621795 (+) 804 WP_002279972.1 MBL fold metallo-hydrolase Regulator
  FNL60_RS03400 (SM3g_06060) rnc 621902..622597 (+) 696 WP_002266141.1 ribonuclease III -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=73521 FNL60_RS03385 WP_002262930.1 618943..619650(+) (vicR) [Streptococcus mutans strain NBRC 13955]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=73521 FNL60_RS03385 WP_002262930.1 618943..619650(+) (vicR) [Streptococcus mutans strain NBRC 13955]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGACTTGATTATATTGGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTTAGAAAAAACAGCCATGTTCCAATTATTATGTTATCAGCT
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGTGCTGATGATTATGTGACTAAACCTTTTTCTAATCGTGA
ATTACTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCCGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATCTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAGTTA
ACTCACCGTGAGTTTGAGTTGTTGCATCACTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTTACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTATTACATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451

Multiple sequence alignment