Detailed information NTG0073520

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FNL60_RS03360
• Genome accession: NZ_AP019720
• Coordinates: 614663..615544 (+)
• Length: 293 a.a.
• NCBI ID: WP_002262935.1
• Uniprot ID: Q8DT59
• Organism: Streptococcus mutans strain NBRC 13955
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 609663..620544

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FNL60_RS03330 (SM3g_05920)	-	609848..610726 (+)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-
FNL60_RS03335 (SM3g_05930)	atpD	610752..612158 (+)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
FNL60_RS03340 (SM3g_05940)	-	612172..612588 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
FNL60_RS03345 (SM3g_05950)	-	612860..613093 (+)	234	WP_002285829.1	DUF1146 family protein	-
FNL60_RS03350 (SM3g_05960)	murA	613159..614430 (+)	1272	WP_002262937.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FNL60_RS03355 (SM3g_05970)	-	614433..614621 (+)	189	WP_002279970.1	DNA-directed RNA polymerase subunit beta	-
FNL60_RS03360 (SM3g_05980)	endA	614663..615544 (+)	882	WP_002262935.1	DNA/RNA non-specific endonuclease	Machinery gene
FNL60_RS03365 (SM3g_05990)	-	615612..616262 (-)	651	WP_002279971.1	amino acid ABC transporter permease	-
FNL60_RS03370 (SM3g_06000)	-	616277..616981 (-)	705	WP_002264823.1	amino acid ABC transporter permease	-
FNL60_RS03375 (SM3g_06010)	-	616999..617811 (-)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
FNL60_RS03380 (SM3g_06020)	-	617808..618590 (-)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
FNL60_RS03385 (SM3g_06030)	vicR	618943..619650 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32130.72 Da
• Isoelectric Point: 9.5337

>NTDB_id=73520 FNL60_RS03360 WP_002262935.1 614663..615544(+) (endA) [Streptococcus mutans strain NBRC 13955]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=73520 FNL60_RS03360 WP_002262935.1 614663..615544(+) (endA) [Streptococcus mutans strain NBRC 13955]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

3D structure

• AlphaFold DB: Q8DT59

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512