Detailed information NTG0734512

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: P4831_RS09880
• Genome accession: NZ_CP120842
• Coordinates: 1970643..1972526 (-)
• Length: 627 a.a.
• NCBI ID: WP_277812465.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain ZFM559
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 1965643..1977526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P4831_RS09850	-	1966048..1966728 (-)	681	WP_003130794.1	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	-
P4831_RS09855	macP	1966761..1967039 (-)	279	WP_003130796.1	cell wall synthase accessory phosphoprotein MacP	-
P4831_RS09860	-	1967032..1967616 (-)	585	WP_012898439.1	NUDIX hydrolase	-
P4831_RS09865	glmU	1967721..1969097 (-)	1377	WP_003130798.1	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	-
P4831_RS09870	proC	1969325..1970113 (+)	789	WP_012898440.1	pyrroline-5-carboxylate reductase	-
P4831_RS09875	rpsO	1970192..1970461 (-)	270	WP_010906184.1	30S ribosomal protein S15	-
P4831_RS09880	pknB	1970643..1972526 (-)	1884	WP_277812465.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
P4831_RS09885	-	1972526..1973302 (-)	777	WP_003130802.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
P4831_RS09890	rsmB	1973383..1974657 (-)	1275	WP_014570715.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
P4831_RS09900	-	1975584..1976006 (-)	423	WP_023164503.1	protein-export chaperone SecB	-
P4831_RS09905	-	1976006..1976308 (-)	303	WP_023164504.1	hypothetical protein	-
P4831_RS09910	-	1976322..1976843 (-)	522	WP_043994824.1	hypothetical protein	-

Sequence

Protein

• Length: 627 a.a.
• Molecular weight: 67947.03 Da
• Isoelectric Point: 4.8251

>NTDB_id=734512 P4831_RS09880 WP_277812465.1 1970643..1972526(-) (pknB) [Lactococcus lactis strain ZFM559]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVGNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKIPNVTNSTLSQAKSKIKDAKLKVGTVHKQQSSTI
AEGKVIKTDPTSGTTVRSNRSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPNVGT
SVDPTQEIVVTYSVYTAPSSSSTTSESTTTSETSSSTTSSTSSSTTSQPSTDNNNSSKESSTTSSSS

Nucleotide

• Length: 1884 bp

>NTDB_id=734512 P4831_RS09880 WP_277812465.1 1970643..1972526(-) (pknB) [Lactococcus lactis strain ZFM559]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGTGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAGCTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATTAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGGAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CACTTAGCCAAGCAAAAAGCAAAATTAAAGATGCAAAACTTAAAGTGGGAACAGTTCATAAACAACAAAGTTCAACGATT
GCTGAAGGAAAAGTTATCAAGACTGATCCAACTAGTGGAACAACCGTGAGATCTAATAGATCCGTTGATATCTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAATCAACAAGCTGATGGTTATGTTTACTCAGTCTATCCAAATGTAGGGACA
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGCGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACTACGACGTCTGAAACTTCATCAAGTACAACTTCAAGTACTTCAAGCTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAGCAAAGAATCTTCAACAACGTCATCAAGTAGTTGA

Domains

Predicted by InterProScan.

• PASTA domain (PASTA) (365-428)

• PASTA domain (PASTA) (506-573)

• PASTA domain (PASTA) (434-501)

• Protein kinase domain (Pkinase) (12-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	49.081	86.762	0.426
stkP/pknB	Streptococcus salivarius strain HSISS4	51.252	82.775	0.424
stkP	Streptococcus pneumoniae TIGR4	48.024	80.702	0.388
stkP	Streptococcus pneumoniae D39	47.826	80.702	0.386
stkP	Streptococcus pneumoniae R6	47.826	80.702	0.386
stkP	Streptococcus pneumoniae Rx1	47.628	80.702	0.384