Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   N7K38_RS02055 Genome accession   NZ_CP104762
Coordinates   392765..394063 (-) Length   432 a.a.
NCBI ID   WP_010747024.1    Uniprot ID   -
Organism   Enterococcus raffinosus strain ATCC 49464     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 387765..399063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N7K38_RS02020 (N7K38_02020) - 388252..389172 (+) 921 WP_010747031.1 nucleoside hydrolase -
  N7K38_RS02025 (N7K38_02025) - 389263..390156 (+) 894 WP_010747030.1 SDR family oxidoreductase -
  N7K38_RS02030 (N7K38_02030) - 390195..390530 (-) 336 WP_010747029.1 hypothetical protein -
  N7K38_RS02035 (N7K38_02035) - 390795..391112 (+) 318 WP_010747028.1 thioredoxin family protein -
  N7K38_RS02040 (N7K38_02040) - 391122..391577 (+) 456 WP_010747027.1 universal stress protein -
  N7K38_RS02045 (N7K38_02045) ytpR 391690..392301 (+) 612 WP_010747026.1 YtpR family tRNA-binding protein -
  N7K38_RS02050 (N7K38_02050) - 392472..392657 (+) 186 WP_010747025.1 hypothetical protein -
  N7K38_RS02055 (N7K38_02055) htrA 392765..394063 (-) 1299 WP_010747024.1 S1C family serine protease Regulator
  N7K38_RS02060 (N7K38_02060) rlmH 394523..395002 (+) 480 WP_010747023.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  N7K38_RS02065 (N7K38_02065) - 395081..395326 (+) 246 WP_010747022.1 DUF4279 domain-containing protein -
  N7K38_RS02070 (N7K38_02070) - 396017..396793 (+) 777 WP_010747021.1 acetoin reductase -
  N7K38_RS02075 (N7K38_02075) - 396881..397366 (+) 486 WP_010747020.1 PTS sugar transporter subunit IIB -
  N7K38_RS02080 (N7K38_02080) - 397380..398174 (+) 795 WP_010747019.1 PTS sugar transporter subunit IIC -
  N7K38_RS02085 (N7K38_02085) - 398177..399031 (+) 855 WP_010747018.1 PTS system mannose/fructose/sorbose family transporter subunit IID -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 45241.49 Da        Isoelectric Point: 4.7980

>NTDB_id=732096 N7K38_RS02055 WP_010747024.1 392765..394063(-) (htrA) [Enterococcus raffinosus strain ATCC 49464]
MIRKDITPTPKKSPGFFRRFGISLLGGVLGAVLTIGIFYVASGSLLSPSNQNASGSPSAGNTKVSNMKVDVNSDITEAAS
KVQDAVVSVINLQKQQSQSGLGGFSDIFGNRNDDQQSQDDSGQLEEASEGSGVIYKLEGNTAYIVTNNHVVEKQDGLEVL
LKDGSKVKATLVGTDSYTDLAVLKVESDKVANIKPATFGDSSSLKVGEPAIALGSPLGSQYANSVTSGIISSLNRQVVNQ
NDEGQTVNINAIQTDAAINPGNSGGPLVNMAGQVVGINSSKIVQTESNVSVEGIGFAIPSNDVVNVINQLEKDGKVIRPA
LGITMASLSDLSTEQVSEIVKVPSSVTQGVVVGSVQSSTPADQAGLKKYDVITKIDDTDVSSGVELQSELYKHKVGDTVK
ITYYRQDKKNTVSVKLSIDSNSLKSNSQQGNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=732096 N7K38_RS02055 WP_010747024.1 392765..394063(-) (htrA) [Enterococcus raffinosus strain ATCC 49464]
ATGATAAGAAAAGACATTACCCCAACACCCAAAAAGTCACCCGGTTTTTTTAGACGGTTTGGGATTAGTTTATTAGGCGG
TGTACTTGGCGCTGTCTTAACAATAGGAATCTTTTACGTAGCGAGCGGTTCGTTACTATCTCCAAGTAATCAAAACGCCA
GCGGCTCGCCTAGTGCGGGTAACACGAAGGTCAGTAACATGAAGGTTGATGTAAACTCTGATATTACCGAAGCAGCCAGC
AAGGTGCAAGACGCGGTTGTTTCTGTTATTAATTTGCAGAAGCAACAATCACAAAGCGGCTTAGGCGGCTTCTCTGATAT
ATTCGGTAATAGAAATGATGATCAGCAGTCGCAAGATGATAGTGGACAACTGGAAGAAGCTTCTGAAGGTTCCGGTGTCA
TCTACAAGTTGGAGGGCAATACCGCCTACATCGTTACAAATAATCACGTTGTGGAAAAACAAGATGGCTTGGAAGTATTG
TTAAAGGATGGTTCAAAAGTGAAGGCAACCTTAGTCGGTACGGATTCCTATACTGACTTGGCTGTTTTAAAGGTTGAATC
AGACAAAGTCGCTAACATCAAACCCGCAACTTTTGGTGATTCTAGCAGCTTAAAGGTTGGTGAACCAGCAATCGCGTTAG
GTTCTCCACTAGGCTCACAGTACGCTAACTCAGTGACTTCAGGGATTATTTCTTCCTTGAATCGTCAAGTAGTCAACCAA
AATGATGAAGGGCAAACCGTCAACATCAATGCAATCCAAACAGATGCAGCTATTAACCCTGGTAACTCTGGCGGTCCGTT
AGTCAACATGGCTGGTCAAGTAGTGGGTATCAACTCTAGTAAGATCGTTCAGACAGAGTCAAATGTCAGTGTGGAAGGAA
TCGGCTTTGCTATTCCAAGTAATGATGTAGTGAACGTTATTAACCAGCTTGAAAAAGATGGGAAAGTAATTCGCCCAGCT
CTAGGCATTACGATGGCTAGCCTATCTGATCTTTCGACTGAACAAGTAAGTGAGATTGTTAAGGTACCAAGTTCTGTTAC
TCAAGGAGTCGTGGTGGGAAGCGTACAATCATCTACACCAGCGGATCAGGCAGGCTTGAAGAAGTATGATGTCATCACAA
AAATCGATGATACCGATGTTTCATCAGGTGTCGAACTGCAATCTGAATTGTACAAACATAAAGTCGGCGATACAGTGAAA
ATCACCTACTATCGTCAAGATAAGAAAAATACAGTTTCAGTAAAATTGAGCATTGATTCGAATTCATTGAAATCAAACTC
ACAACAAGGGAACCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(319-416)

Trypsin-like peptidase domain (Trypsin_2)

(130-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

49.762

97.222

0.484
  htrA Streptococcus mutans UA159

50

95.37

0.477
  htrA Streptococcus mitis NCTC 12261

49.756

94.907

0.472
  htrA Streptococcus pneumoniae TIGR4

54.571

81.019

0.442
  htrA Streptococcus pneumoniae D39

54.571

81.019

0.442
  htrA Streptococcus pneumoniae Rx1

54.571

81.019

0.442
  htrA Streptococcus pneumoniae R6

54.571

81.019

0.442