Detailed information NTG0731472

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: N5A89_RS01845
• Genome accession: NZ_CP104714
• Coordinates: 421839..423989 (+)
• Length: 716 a.a.
• NCBI ID: WP_122211242.1
• Uniprot ID: A0AB37RJE7
• Organism: Lactiplantibacillus pentosus strain 68-1
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 416839..428989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N5A89_RS01805 (N5A89_01805)	-	417743..418504 (-)	762	WP_122211248.1	CPBP family intramembrane glutamic endopeptidase	-
N5A89_RS01810 (N5A89_01810)	-	418606..418764 (-)	159	WP_122211247.1	bacteriocin	-
N5A89_RS01815 (N5A89_01815)	-	418787..418957 (-)	171	WP_122211246.1	bacteriocin	-
N5A89_RS01820 (N5A89_01820)	-	419182..419343 (-)	162	WP_122211245.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
N5A89_RS01825 (N5A89_01825)	-	419360..419509 (-)	150	WP_165860553.1	hypothetical protein	-
N5A89_RS01830 (N5A89_01830)	-	419701..420258 (-)	558	Protein_364	IS5 family transposase	-
N5A89_RS01835 (N5A89_01835)	-	420651..420830 (+)	180	WP_152705569.1	hypothetical protein	-
N5A89_RS01840 (N5A89_01840)	-	421059..421727 (+)	669	WP_122211243.1	CPBP family intramembrane glutamic endopeptidase	-
N5A89_RS01845 (N5A89_01845)	comA	421839..423989 (+)	2151	WP_122211242.1	peptide cleavage/export ABC transporter	Regulator
N5A89_RS01850 (N5A89_01850)	-	424005..425381 (+)	1377	WP_122211241.1	HlyD family secretion protein	-
N5A89_RS16175 (N5A89_01855)	-	425905..426120 (+)	216	WP_122211240.1	type II toxin-antitoxin system RelE/ParE family toxin	-
N5A89_RS01860 (N5A89_01860)	-	426134..426427 (+)	294	WP_088770109.1	HigA family addiction module antitoxin	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80249.92 Da
• Isoelectric Point: 6.2438

>NTDB_id=731472 N5A89_RS01845 WP_122211242.1 421839..423989(+) (comA) [Lactiplantibacillus pentosus strain 68-1]
MRWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFELQDLPL
PFIVHVTKNGDLQHFYVVVKASKTHVVIADPDPTVAVINMPRERFEKEWSGVALFFAPKSEYKPVKQDKGSLWGFVPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAMVALGLIIFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVVIMGVILVIQNMTLFWITLLSLPVYAIVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQSLKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEESRPIHNESQLNG
DIKIQNVSYRYGYGENVLDDINLTIQQQDKVAIVGMSGSGKSTLVKLLIDFYQPNNGDVMLNGFNVKNIDKHTLRTHINY
IPQEPYIFSGTIEENIRLGNRDGVTQDDITNACQLALIDTDINKMSMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKRLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGQVVEEGTHAALLGEHGYYYDLINS

Nucleotide

• Length: 2151 bp

>NTDB_id=731472 N5A89_RS01845 WP_122211242.1 421839..423989(+) (comA) [Lactiplantibacillus pentosus strain 68-1]
ATGCGCTGGAGAAACTATGTTGCTCAAGTTGACGAGATGGATTGTGGTGTCGCAGCTTTAGCAATGATTTTAAAGAATTA
TGGTTCAACAACATCTTTGGCTTATCTAAGAAATATTGCTAAAACGAGTCTGGAAGGGACTACGGCATTAGGATTAGTGA
AAACGGCCGAAAAGTTAGGCTTTGAAACCAAAGCAATTCAGGCAGATATGAGCCTTTTTGAGTTGCAAGATCTACCCTTA
CCATTTATTGTGCATGTCACTAAAAATGGTGATTTACAGCATTTTTATGTCGTTGTGAAGGCCTCTAAAACACATGTTGT
GATTGCTGATCCAGATCCAACAGTTGCGGTTATTAACATGCCCAGAGAACGATTTGAAAAGGAATGGTCAGGAGTAGCAC
TGTTCTTTGCACCAAAGTCAGAGTACAAACCTGTTAAGCAAGATAAAGGATCGCTATGGGGCTTTGTTCCAAGCTTATTA
AAGCAACGTCGATTGGTGATTAATATTGTCTTGGCTGCCGTTTTAATTACCATTATTAGCATCTGTGGTTCTTATTTCTT
ACAGGCAGTGATTGATACTTATATTCCCAACAATATGCACAGTACATTGGCGATGGTTGCACTTGGATTGATCATTTTTT
ATACTTTTCAAGCCATTTTCACCTACGCTCAGAACTTTCTGTTAGCGGTTTTAGGGCAGCGGTTATCCATTGAAATAATT
CTTGGCTATATTAGACATGTCTTTGAGTTGCCAATGAGTTTTTTTGCTACGCGACGAACAGGGGAGATTGTATCTCGGTT
TACCGATGCTAGTAAGATTATTGATGCTTTAGCCAGTACGATTGTCTCACTATTCTTAGATGTAAGCATTGTCGTCATTA
TGGGTGTAATTTTGGTAATTCAAAATATGACGCTTTTTTGGATTACACTGCTATCACTACCCGTTTATGCAATTGTTATT
TTAGCGTTTAATAAATCTTTTGAGCGTCTTAATCAAAAGGAAATGGAAAGCAATGCAATCTTGAGCTCAGCTATAATTGA
AGATTTGCATGGCATTGAAACGGTTAAGGCTTTGAATGGCGAGACAGAACGTTATCAAAAAATCGATTCAGAGTTTGTTG
ACTATTTACGCAAAAGCTTAGCATATCTGAAAGCGGACACGCTGCAACAATCACTAAAATTATTTATTCAGCTAGTCTTG
GAAGTAGTCGTTCTCTGGGTAGGAGCTAATTTGGTTATTCATAATCAGTTGTCGGTTGGGGAACTTATGACATATAACGC
ATTGCTAGCTTACTTTGTGAATCCATTGCAAAATATTATTAATCTACAGACTAAGTTACAAAGTGCCAAAGTAGCTAATA
ATCGACTGAATGAAGTTTATTTGGTTGCCAGTGAATTTGAAGAATCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGATCCAAAATGTCAGCTATCGGTATGGTTATGGTGAAAATGTTTTAGATGATATTAATTTGACAATCCAACA
ACAGGATAAGGTAGCGATTGTTGGGATGAGCGGCTCAGGAAAGTCTACATTGGTCAAACTACTTATAGATTTCTATCAGC
CAAATAATGGTGATGTCATGCTGAATGGCTTCAACGTCAAAAATATCGATAAACATACGCTGCGTACTCATATTAACTAC
ATTCCACAGGAACCTTATATTTTCTCGGGAACTATCGAAGAAAATATAAGATTGGGAAATCGCGATGGTGTGACTCAGGA
TGATATTACGAATGCTTGCCAGTTGGCGTTGATTGATACCGATATCAATAAGATGTCGATGCAGTATCAAACTAAGTTGG
ATGAAAATGGTAATACTTTATCTGGTGGTCAGCGTCAGCGATTAACGATTGCGAGAGCGTTATTATCTCCAGCCCAAGTC
TTAATATTTGATGAATCAACAAGCGGCTTGGATGCGATTACCGAAAAAAGATTGATAGATAATCTAGTGGCAATGACCGA
TAAAACGATTATATTTATTGCCCATCGGTTGTCAATTGCCAAACGGACCAATCATATCATCGTTTTACATGATGGCCAGG
TCGTTGAAGAAGGAACGCATGCGGCATTGTTGGGCGAACATGGTTACTACTATGATTTAATTAATAGCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (498-648)

• Peptidase C39 family (Peptidase_C39) (5-140)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	59.607	99.581	0.594
comA	Streptococcus pneumoniae Rx1	59.327	99.581	0.591
comA	Streptococcus pneumoniae D39	59.327	99.581	0.591
comA	Streptococcus pneumoniae R6	59.327	99.581	0.591
comA	Streptococcus pneumoniae TIGR4	59.187	99.581	0.589
comA	Streptococcus mitis SK321	59.046	99.581	0.588
comA	Streptococcus gordonii str. Challis substr. CH1	57.821	100	0.578
comA/nlmT	Streptococcus mutans UA159	54.749	100	0.547