Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   N4S13_RS01850 Genome accession   NZ_CP104392
Coordinates   375846..377144 (-) Length   432 a.a.
NCBI ID   WP_010747024.1    Uniprot ID   -
Organism   Enterococcus raffinosus strain HG-5     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 370846..382144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4S13_RS01815 (N4S13_01815) - 371333..372253 (+) 921 WP_010747031.1 nucleoside hydrolase -
  N4S13_RS01820 (N4S13_01820) - 372344..373237 (+) 894 WP_010747030.1 SDR family oxidoreductase -
  N4S13_RS01825 (N4S13_01825) - 373276..373611 (-) 336 WP_010747029.1 hypothetical protein -
  N4S13_RS01830 (N4S13_01830) - 373876..374193 (+) 318 WP_010747028.1 thioredoxin family protein -
  N4S13_RS01835 (N4S13_01835) - 374203..374658 (+) 456 WP_010747027.1 universal stress protein -
  N4S13_RS01840 (N4S13_01840) ytpR 374771..375382 (+) 612 WP_010747026.1 YtpR family tRNA-binding protein -
  N4S13_RS01845 (N4S13_01845) - 375553..375738 (+) 186 WP_010747025.1 hypothetical protein -
  N4S13_RS01850 (N4S13_01850) htrA 375846..377144 (-) 1299 WP_010747024.1 S1C family serine protease Regulator
  N4S13_RS01855 (N4S13_01855) rlmH 377604..378083 (+) 480 WP_010747023.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  N4S13_RS01860 (N4S13_01860) - 378112..378726 (+) 615 WP_070509211.1 hypothetical protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 45241.49 Da        Isoelectric Point: 4.7980

>NTDB_id=729472 N4S13_RS01850 WP_010747024.1 375846..377144(-) (htrA) [Enterococcus raffinosus strain HG-5]
MIRKDITPTPKKSPGFFRRFGISLLGGVLGAVLTIGIFYVASGSLLSPSNQNASGSPSAGNTKVSNMKVDVNSDITEAAS
KVQDAVVSVINLQKQQSQSGLGGFSDIFGNRNDDQQSQDDSGQLEEASEGSGVIYKLEGNTAYIVTNNHVVEKQDGLEVL
LKDGSKVKATLVGTDSYTDLAVLKVESDKVANIKPATFGDSSSLKVGEPAIALGSPLGSQYANSVTSGIISSLNRQVVNQ
NDEGQTVNINAIQTDAAINPGNSGGPLVNMAGQVVGINSSKIVQTESNVSVEGIGFAIPSNDVVNVINQLEKDGKVIRPA
LGITMASLSDLSTEQVSEIVKVPSSVTQGVVVGSVQSSTPADQAGLKKYDVITKIDDTDVSSGVELQSELYKHKVGDTVK
ITYYRQDKKNTVSVKLSIDSNSLKSNSQQGNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=729472 N4S13_RS01850 WP_010747024.1 375846..377144(-) (htrA) [Enterococcus raffinosus strain HG-5]
ATGATAAGAAAAGACATTACCCCAACACCCAAAAAGTCACCCGGTTTTTTTAGACGGTTTGGGATTAGTTTATTAGGCGG
TGTACTTGGCGCTGTCTTAACAATAGGAATCTTTTACGTAGCGAGCGGTTCGTTACTATCTCCAAGTAATCAAAACGCCA
GCGGCTCGCCTAGTGCGGGTAACACGAAGGTCAGTAACATGAAGGTTGATGTAAACTCTGATATTACCGAAGCAGCCAGC
AAGGTGCAAGACGCGGTTGTTTCTGTTATTAATTTGCAGAAGCAACAATCACAAAGCGGCTTAGGCGGCTTCTCTGATAT
ATTCGGTAATAGAAATGATGATCAGCAGTCGCAAGATGATAGTGGACAACTGGAAGAAGCTTCTGAAGGTTCCGGTGTCA
TCTACAAGTTGGAGGGCAATACCGCCTACATCGTTACAAATAATCACGTTGTGGAAAAACAAGATGGCTTGGAAGTATTG
TTAAAGGATGGTTCAAAAGTGAAGGCAACCTTAGTCGGTACGGATTCCTATACTGACTTGGCTGTTTTAAAGGTTGAATC
AGACAAAGTCGCTAACATCAAACCCGCAACTTTTGGTGATTCTAGCAGCTTAAAGGTTGGTGAACCAGCAATCGCGTTAG
GTTCTCCACTAGGCTCACAGTACGCTAACTCAGTGACTTCAGGGATTATTTCTTCCTTGAATCGTCAAGTAGTCAACCAA
AATGATGAAGGGCAAACCGTCAACATCAATGCAATCCAAACAGATGCAGCTATTAACCCTGGTAACTCTGGCGGTCCGTT
AGTCAACATGGCTGGTCAAGTAGTGGGTATCAACTCTAGTAAGATCGTTCAGACAGAGTCAAATGTCAGTGTGGAAGGAA
TCGGCTTTGCTATTCCAAGTAATGATGTAGTGAACGTTATTAACCAGCTTGAAAAAGATGGGAAAGTAATTCGCCCAGCT
CTAGGCATTACGATGGCTAGCCTATCTGATCTTTCGACTGAACAAGTAAGTGAGATTGTTAAGGTACCAAGTTCTGTTAC
TCAAGGAGTCGTGGTGGGAAGCGTACAATCATCTACACCAGCGGATCAGGCAGGCTTGAAGAAGTATGATGTCATCACAA
AAATCGATGATACCGATGTTTCATCAGGTGTCGAACTGCAATCTGAATTGTACAAACATAAAGTCGGCGATACAGTGAAA
ATCACCTACTATCGTCAAGATAAGAAAAATACAGTTTCAGTAAAATTGAGCATTGATTCGAATTCATTGAAATCAAACTC
ACAACAAGGGAACCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(319-416)

Trypsin-like peptidase domain (Trypsin_2)

(130-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

49.762

97.222

0.484
  htrA Streptococcus mutans UA159

50

95.37

0.477
  htrA Streptococcus mitis NCTC 12261

49.756

94.907

0.472
  htrA Streptococcus pneumoniae TIGR4

54.571

81.019

0.442
  htrA Streptococcus pneumoniae D39

54.571

81.019

0.442
  htrA Streptococcus pneumoniae Rx1

54.571

81.019

0.442
  htrA Streptococcus pneumoniae R6

54.571

81.019

0.442