Detailed information NTG0729351

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: N4R43_RS11470
• Genome accession: NZ_CP104388
• Coordinates: 2277751..2279961 (-)
• Length: 736 a.a.
• NCBI ID: WP_317141310.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain LJL7m20
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2272751..2284961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N4R43_RS11440 (N4R43_11455)	atpA	2272793..2274295 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
N4R43_RS11445 (N4R43_11460)	-	2274482..2275009 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
N4R43_RS11450 (N4R43_11465)	atpF	2275011..2275517 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
N4R43_RS11455 (N4R43_11470)	atpB	2275532..2276245 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
N4R43_RS11460 (N4R43_11475)	-	2276290..2276505 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
N4R43_RS11465 (N4R43_11480)	-	2276690..2277466 (-)	777	WP_058206315.1	alpha/beta hydrolase family protein	-
N4R43_RS11470 (N4R43_11485)	comEC	2277751..2279961 (-)	2211	WP_317141310.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
N4R43_RS11475 (N4R43_11490)	comEA	2279942..2280589 (-)	648	WP_058223210.1	ComEA family DNA-binding protein	Machinery gene
N4R43_RS11480 (N4R43_11495)	-	2280649..2282010 (-)	1362	WP_021214597.1	ABC transporter permease	-
N4R43_RS11485 (N4R43_11500)	-	2282007..2282939 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
N4R43_RS11490 (N4R43_11505)	-	2283044..2283442 (-)	399	WP_004255236.1	hypothetical protein	-
N4R43_RS11495 (N4R43_11510)	-	2283551..2284114 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84457.13 Da
• Isoelectric Point: 9.6386

>NTDB_id=729351 N4R43_RS11470 WP_317141310.1 2277751..2279961(-) (comEC) [Lactococcus lactis strain LJL7m20]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPLLLVMGSFFLVVKMDTIKNNENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQDI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDILAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLALGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNSDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=729351 N4R43_RS11470 WP_317141310.1 2277751..2279961(-) (comEC) [Lactococcus lactis strain LJL7m20]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCACTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAATGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGGATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATATCCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGCTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACTCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.766	100	0.768
comEC/celB	Streptococcus mitis SK321	44.355	100	0.448
comEC/celB	Streptococcus mitis NCTC 12261	44.07	100	0.444
comEC/celB	Streptococcus pneumoniae TIGR4	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae Rx1	42.665	100	0.431
comEC/celB	Streptococcus pneumoniae D39	42.665	100	0.431
comEC/celB	Streptococcus pneumoniae R6	42.665	100	0.431