Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   N2A93_RS01995 Genome accession   NZ_CP104046
Coordinates   360124..360879 (+) Length   251 a.a.
NCBI ID   WP_004234185.1    Uniprot ID   -
Organism   Streptococcus parauberis strain KSP14     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 355124..365879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A93_RS01980 (N2A93_01980) - 355428..356996 (-) 1569 WP_004234187.1 ABC transporter substrate-binding protein/permease -
  N2A93_RS01985 (N2A93_01985) - 357202..359106 (+) 1905 WP_004234186.1 DUF2207 domain-containing protein -
  N2A93_RS01990 (N2A93_01990) - 359181..360020 (+) 840 WP_003108565.1 undecaprenyl-diphosphate phosphatase -
  N2A93_RS01995 (N2A93_01995) mecA 360124..360879 (+) 756 WP_004234185.1 adaptor protein MecA Regulator
  N2A93_RS02000 (N2A93_02000) - 360886..362043 (+) 1158 WP_004234184.1 glycosyltransferase family 4 protein -
  N2A93_RS02005 (N2A93_02005) sufC 362168..362938 (+) 771 WP_004234182.1 Fe-S cluster assembly ATPase SufC -
  N2A93_RS02010 (N2A93_02010) sufD 363027..364289 (+) 1263 WP_003102572.1 Fe-S cluster assembly protein SufD -
  N2A93_RS02015 (N2A93_02015) - 364314..365540 (+) 1227 WP_004234180.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29155.84 Da        Isoelectric Point: 4.1299

>NTDB_id=727233 N2A93_RS01995 WP_004234185.1 360124..360879(+) (mecA) [Streptococcus parauberis strain KSP14]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKDINFEDLAELGDISQMTPEDFFKTIEKNMMEKGDVDAHQKLEKIEEMLEDASAQAQEQAKVAEQEEYEAEVLDYVHFV
LSFASIEDAINFSKTIDFPIEASELYKESKSYHMTILLDVQNQPSYYANVSYARLIEHANPGIRTRAYLQEHGIQLIEDN
AVEELKKIEMV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=727233 N2A93_RS01995 WP_004234185.1 360124..360879(+) (mecA) [Streptococcus parauberis strain KSP14]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATAACGATCAGCATGGATGATTTAGAAGAAAGAGGTATGGAATT
AAAAGATTTCTTGATTCCACAAGAAAAGACCGAAGAATTTTTCTATTCAGTTATGGATGAACTTGATTTACCAGAAAACT
TTAAAGATAGTGGTATGCTTAGTTTCAGAGTGACACCTCGAAAAGACCGATTAGATGTCTTTGTTACAAAATCAGAATTA
AGTAAAGACATCAATTTTGAAGATTTAGCTGAACTAGGTGATATTTCACAAATGACGCCTGAAGATTTTTTCAAAACGAT
TGAAAAAAACATGATGGAAAAAGGTGATGTCGATGCTCACCAAAAATTAGAGAAAATTGAAGAAATGCTTGAGGATGCCT
CTGCTCAGGCGCAGGAGCAAGCAAAAGTTGCTGAACAAGAAGAGTATGAAGCAGAAGTTCTTGATTATGTTCACTTCGTA
TTGAGTTTTGCTTCTATTGAAGATGCAATTAATTTTTCAAAAACAATTGATTTCCCAATTGAAGCATCTGAGTTATATAA
GGAAAGCAAAAGTTATCACATGACTATTTTATTAGATGTTCAAAATCAACCTTCATATTATGCAAATGTTAGCTATGCAC
GTTTAATTGAACATGCTAATCCTGGGATTAGGACCAGAGCTTATTTACAAGAGCATGGCATTCAATTAATTGAAGATAAT
GCTGTTGAAGAATTGAAAAAAATTGAGATGGTGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.113

98.805

0.633
  mecA Streptococcus thermophilus LMD-9

56.855

98.805

0.562
  mecA Streptococcus thermophilus LMG 18311

56.048

98.805

0.554
  mecA Streptococcus pneumoniae Rx1

47.826

100

0.482
  mecA Streptococcus pneumoniae D39

47.826

100

0.482
  mecA Streptococcus pneumoniae R6

47.826

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.826

100

0.482