NTDB

Overview

Name	comGF/cglF	Type	Machinery gene
Locus tag	P1T45_RS01120	Genome accession	NZ_CP119427
Coordinates	178790..179227 (+)	Length	145 a.a.
NCBI ID	WP_003102915.1	Uniprot ID	A0ABN0IPC0
Organism	Streptococcus parauberis strain KSP45
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 173790..184227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1T45_RS01090 (P1T45_01090)	-	175837..176004 (+)	168	WP_308695556.1	hypothetical protein	-
P1T45_RS01095 (P1T45_01095)	-	175989..176444 (+)	456	WP_003108647.1	phage holin family protein	-
P1T45_RS11380	-	176560..176886 (+)	327	Protein_169	peptidoglycan amidohydrolase family protein	-
P1T45_RS11385	-	176926..177171 (+)	246	Protein_170	lysin	-
P1T45_RS01105 (P1T45_01105)	comGC	177824..178144 (+)	321	WP_003108645.1	competence type IV pilus major pilin ComGC	Machinery gene
P1T45_RS01110 (P1T45_01110)	comGD	178134..178541 (+)	408	WP_243619590.1	competence type IV pilus minor pilin ComGD	Machinery gene
P1T45_RS01115 (P1T45_01115)	comGE	178513..178812 (+)	300	WP_003108643.1	competence type IV pilus minor pilin ComGE	Machinery gene
P1T45_RS01120 (P1T45_01120)	comGF/cglF	178790..179227 (+)	438	WP_003102915.1	competence type IV pilus minor pilin ComGF	Machinery gene
P1T45_RS01125 (P1T45_01125)	comGG	179181..179702 (+)	522	WP_308695560.1	competence type IV pilus minor pilin ComGG	-
P1T45_RS01130 (P1T45_01130)	comGH	179809..180765 (+)	957	WP_003103712.1	class I SAM-dependent methyltransferase	Machinery gene
P1T45_RS01135 (P1T45_01135)	-	180821..182014 (+)	1194	WP_003108638.1	acetate kinase	-
P1T45_RS01140 (P1T45_01140)	-	182125..182337 (+)	213	WP_003108636.1	helix-turn-helix transcriptional regulator	-
P1T45_RS01145 (P1T45_01145)	-	182330..182782 (+)	453	WP_003108634.1	hypothetical protein	-
P1T45_RS01150 (P1T45_01150)	-	182791..183444 (+)	654	WP_003108632.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

Download Length: 145 a.a. Molecular weight: 16538.25 Da Isoelectric Point: 9.7525

                                >NTDB_id=726344 P1T45_RS01120 WP_003102915.1 178790..179227(+) (comGF/cglF) [Streptococcus parauberis strain KSP45]

MLQKLVTKGFTLFEALIALLVISGSLLVYQGLTKSTFANMNYLSQSDQDSWLLFANQFRAELEGSQFIEIKGKKMLVKKD

EKVVSFRLTEKNDFRKSAASGKGLNPMLLNLQDIQMTTVNHQLTLHLIWQSGLERDFIYAFEKPS

Nucleotide

Download Length: 438 bp

                                >NTDB_id=726344 P1T45_RS01120 WP_003102915.1 178790..179227(+) (comGF/cglF) [Streptococcus parauberis strain KSP45]

ATGTTACAAAAATTAGTGACTAAGGGTTTTACCTTATTTGAAGCCTTAATTGCACTTTTAGTTATCTCTGGATCTCTACT

GGTTTATCAAGGTTTAACTAAGTCAACGTTTGCCAATATGAACTATCTAAGTCAAAGTGATCAAGATAGTTGGCTCTTAT

TTGCAAATCAGTTTAGAGCTGAATTGGAAGGTTCACAATTTATTGAAATTAAAGGAAAAAAAATGCTTGTTAAAAAGGAT

GAAAAGGTAGTTTCTTTTAGATTAACTGAAAAAAATGACTTTAGAAAATCGGCAGCTAGTGGGAAAGGCTTAAATCCAAT

GTTGTTAAACTTACAGGATATTCAAATGACGACAGTAAATCACCAACTAACTCTTCATTTGATCTGGCAAAGTGGCCTGG

AAAGGGATTTTATCTATGCATTTGAGAAGCCAAGTTAA

Domains

Predicted by InterProScan.

Putative Competence protein ComGF (ComGF)

(41-134)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGF/cglF	Streptococcus mitis SK321	44.928	95.172	0.428
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	94.483	0.414
comGF	Streptococcus mutans UA140	42.029	95.172	0.4
comGF	Streptococcus mutans UA159	41.304	95.172	0.393
comGF/cglF	Streptococcus pneumoniae R6	40.58	95.172	0.386
comGF/cglF	Streptococcus pneumoniae TIGR4	40.58	95.172	0.386
comGF/cglF	Streptococcus pneumoniae D39	40.58	95.172	0.386
comGF/cglF	Streptococcus pneumoniae Rx1	40.58	95.172	0.386

Detailed information NTG0726344