Detailed information
Bioinformatically predicted
Overview
| Name | cclA/cilC | Type | Machinery gene |
| Locus tag | EL263_RS08760 | Genome accession | NZ_AP018938 |
| Coordinates | 1651334..1651993 (+) | Length | 219 a.a. |
| NCBI ID | WP_000565001.1 | Uniprot ID | A0A0B7M7B9 |
| Organism | Streptococcus pneumoniae strain ATCC 49619 | ||
| Function | processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
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Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1641512..1674925 | 1651334..1651993 | within | 0 |
Gene organization within MGE regions
Location: 1641512..1674925
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL263_RS08710 (SPAT_1654) | - | 1641512..1642282 (-) | 771 | WP_000229339.1 | sulfite exporter TauE/SafE family protein | - |
| EL263_RS08715 (SPAT_1655) | - | 1642297..1643145 (-) | 849 | WP_000782429.1 | formylglycine-generating enzyme family protein | - |
| EL263_RS08720 (SPAT_1656) | - | 1643142..1644617 (-) | 1476 | WP_050096564.1 | arylsulfatase | - |
| EL263_RS08725 (SPAT_1657) | - | 1644940..1646295 (-) | 1356 | WP_001865112.1 | PTS sugar transporter subunit IIC | - |
| EL263_RS08730 (SPAT_1658) | - | 1646305..1646622 (-) | 318 | WP_001005887.1 | PTS lactose/cellobiose transporter subunit IIA | - |
| EL263_RS08735 (SPAT_1659) | - | 1646639..1646956 (-) | 318 | WP_050221104.1 | PTS sugar transporter subunit IIB | - |
| EL263_RS08740 (SPAT_1660) | - | 1646971..1647867 (-) | 897 | WP_001865114.1 | hypothetical protein | - |
| EL263_RS08745 (SPAT_1661) | - | 1647870..1649132 (-) | 1263 | WP_000413342.1 | PTS sugar transporter subunit IIC | - |
| EL263_RS08750 (SPAT_1662) | - | 1649412..1650590 (+) | 1179 | WP_001865373.1 | ROK family transcriptional regulator | - |
| EL263_RS08755 (SPAT_1663) | - | 1650818..1651264 (-) | 447 | WP_000155432.1 | GNAT family N-acetyltransferase | - |
| EL263_RS08760 (SPAT_1664) | cclA/cilC | 1651334..1651993 (+) | 660 | WP_000565001.1 | prepilin peptidase | Machinery gene |
| EL263_RS08765 (SPAT_1665) | - | 1652045..1653196 (-) | 1152 | WP_001865397.1 | XRE family transcriptional regulator | - |
| EL263_RS08770 (SPAT_1666) | - | 1653211..1653942 (-) | 732 | WP_000934016.1 | hypothetical protein | - |
| EL263_RS08775 | - | 1654162..1654272 (+) | 111 | Protein_1665 | prepilin peptidase | - |
| EL263_RS08780 (SPAT_1667) | trpA | 1654244..1655020 (-) | 777 | WP_001127027.1 | tryptophan synthase subunit alpha | - |
| EL263_RS08785 (SPAT_1668) | trpB | 1655013..1656236 (-) | 1224 | WP_024477621.1 | tryptophan synthase subunit beta | - |
| EL263_RS08790 (SPAT_1669) | - | 1656214..1656813 (-) | 600 | WP_000169888.1 | phosphoribosylanthranilate isomerase | - |
| EL263_RS08795 (SPAT_1670) | trpC | 1656800..1657567 (-) | 768 | WP_000076548.1 | indole-3-glycerol phosphate synthase TrpC | - |
| EL263_RS08800 (SPAT_1671) | trpD | 1657564..1658568 (-) | 1005 | WP_000658682.1 | anthranilate phosphoribosyltransferase | - |
| EL263_RS08805 (SPAT_1672) | - | 1658579..1659145 (-) | 567 | WP_000601919.1 | aminodeoxychorismate/anthranilate synthase component II | - |
| EL263_RS08810 (SPAT_1673) | trpE | 1659142..1660503 (-) | 1362 | WP_000439654.1 | anthranilate synthase component I | - |
| EL263_RS11590 | - | 1660875..1661063 (-) | 189 | WP_185739684.1 | hypothetical protein | - |
| EL263_RS08820 (SPAT_1674) | - | 1661733..1662734 (-) | 1002 | WP_000789949.1 | LacI family DNA-binding transcriptional regulator | - |
| EL263_RS08825 (SPAT_1675) | - | 1662842..1663210 (-) | 369 | WP_000656286.1 | hypothetical protein | - |
| EL263_RS08830 (SPAT_1676) | - | 1663306..1664016 (-) | 711 | WP_000127552.1 | MgtC/SapB family protein | - |
| EL263_RS08835 (SPAT_1677) | - | 1664019..1665710 (-) | 1692 | WP_001216185.1 | ABC transporter permease | - |
| EL263_RS08840 (SPAT_1678) | - | 1665722..1666732 (-) | 1011 | WP_050279185.1 | ABC transporter ATP-binding protein | - |
| EL263_RS08845 (SPAT_1679) | - | 1666836..1667903 (-) | 1068 | WP_023930326.1 | extracellular solute-binding protein | - |
| EL263_RS08850 (SPAT_1680) | - | 1667928..1668587 (-) | 660 | WP_000793812.1 | DUF1868 domain-containing protein | - |
| EL263_RS08855 (SPAT_1681) | galE | 1668767..1669777 (-) | 1011 | WP_050198011.1 | UDP-glucose 4-epimerase GalE | - |
| EL263_RS08860 (SPAT_1682) | galT | 1669790..1671265 (-) | 1476 | WP_000848795.1 | UDP-glucose--hexose-1-phosphate uridylyltransferase | - |
| EL263_RS08865 (SPAT_1683) | - | 1671283..1671918 (-) | 636 | WP_050084685.1 | phosphate signaling complex PhoU family protein | - |
| EL263_RS11865 (SPAT_1684) | - | 1671976..1672359 (-) | 384 | WP_001812628.1 | hypothetical protein | - |
| EL263_RS08875 (SPAT_1685) | - | 1672519..1672815 (-) | 297 | WP_000239027.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 219 a.a. Molecular weight: 24820.92 Da Isoelectric Point: 7.2761
>NTDB_id=71955 EL263_RS08760 WP_000565001.1 1651334..1651993(+) (cclA/cilC) [Streptococcus pneumoniae strain ATCC 49619]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV
Nucleotide
Download Length: 660 bp
>NTDB_id=71955 EL263_RS08760 WP_000565001.1 1651334..1651993(+) (cclA/cilC) [Streptococcus pneumoniae strain ATCC 49619]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| cclA/cilC | Streptococcus pneumoniae TIGR4 |
98.174 |
100 |
0.982 |
| cclA/cilC | Streptococcus pneumoniae Rx1 |
96.804 |
100 |
0.968 |
| cclA/cilC | Streptococcus pneumoniae D39 |
96.804 |
100 |
0.968 |
| cclA/cilC | Streptococcus pneumoniae R6 |
96.804 |
100 |
0.968 |
| cclA/cilC | Streptococcus mitis SK321 |
92.237 |
100 |
0.922 |
| cclA/cilC | Streptococcus mitis NCTC 12261 |
87.215 |
100 |
0.872 |