Detailed information NTG0071924

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: EL263_RS00465
• Genome accession: NZ_AP018938
• Coordinates: 79279..80628 (+)
• Length: 449 a.a.
• NCBI ID: WP_000801629.1
• Uniprot ID: A0A0T8X0V4
• Organism: Streptococcus pneumoniae strain ATCC 49619
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 74279..85628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL263_RS00450 (SPAT_0085)	blpU	74754..74984 (+)	231	WP_001093487.1	bacteriocin-like peptide BlpU	-
EL263_RS11950	-	74987..75112 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
EL263_RS00455	-	75362..76679 (-)	1318	Protein_80	ISL3 family transposase	-
EL263_RS00460 (SPAT_0089)	comA	77113..79266 (+)	2154	WP_050221223.1	peptide cleavage/export ABC transporter ComA	Regulator
EL263_RS00465 (SPAT_0090)	comB	79279..80628 (+)	1350	WP_000801629.1	competence pheromone export protein ComB	Regulator
EL263_RS00470 (SPAT_0091)	purC	80798..81505 (+)	708	WP_000043313.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
EL263_RS12025	-	81516..81650 (+)	135	WP_000429436.1	hypothetical protein	-
EL263_RS00480 (SPAT_0092)	-	81707..85432 (+)	3726	WP_114880802.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49525.39 Da
• Isoelectric Point: 5.5618

>NTDB_id=71924 EL263_RS00465 WP_000801629.1 79279..80628(+) (comB) [Streptococcus pneumoniae strain ATCC 49619]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQGGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGTLLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=71924 EL263_RS00465 WP_000801629.1 79279..80628(+) (comB) [Streptococcus pneumoniae strain ATCC 49619]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGGAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGTGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTACCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTAGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A0T8X0V4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae Rx1	99.332	100	0.993
comB	Streptococcus pneumoniae D39	99.332	100	0.993
comB	Streptococcus pneumoniae R6	99.332	100	0.993
comB	Streptococcus pneumoniae TIGR4	99.109	100	0.991
comB	Streptococcus mitis SK321	95.1	100	0.951
comB	Streptococcus mitis NCTC 12261	94.209	100	0.942
comB	Streptococcus gordonii str. Challis substr. CH1	55.778	100	0.559