Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NWE21_RS08835 Genome accession   NZ_CP102748
Coordinates   1771444..1772166 (-) Length   240 a.a.
NCBI ID   WP_012775334.1    Uniprot ID   -
Organism   Streptococcus suis strain Transconjugant cSFJ45     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1766444..1777166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE21_RS08820 (NWE21_08830) sufD 1767670..1768932 (-) 1263 WP_012775333.1 Fe-S cluster assembly protein SufD -
  NWE21_RS08825 (NWE21_08835) sufC 1768949..1769722 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  NWE21_RS08830 (NWE21_08840) - 1770275..1771447 (-) 1173 WP_012027769.1 glycosyltransferase family 4 protein -
  NWE21_RS08835 (NWE21_08845) mecA 1771444..1772166 (-) 723 WP_012775334.1 adaptor protein MecA Regulator
  NWE21_RS08840 (NWE21_08850) - 1772294..1773130 (-) 837 WP_012027770.1 undecaprenyl-diphosphate phosphatase -
  NWE21_RS08845 (NWE21_08855) - 1773257..1774822 (+) 1566 WP_012028491.1 ABC transporter substrate-binding protein/permease -
  NWE21_RS08850 (NWE21_08860) - 1774815..1775558 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  NWE21_RS08855 (NWE21_08865) - 1775684..1775893 (-) 210 WP_009910800.1 hypothetical protein -
  NWE21_RS08860 (NWE21_08870) - 1775979..1776881 (-) 903 WP_012027774.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28000.54 Da        Isoelectric Point: 4.0497

>NTDB_id=718769 NWE21_RS08835 WP_012775334.1 1771444..1772166(-) (mecA) [Streptococcus suis strain Transconjugant cSFJ45]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=718769 NWE21_RS08835 WP_012775334.1 1771444..1772166(-) (mecA) [Streptococcus suis strain Transconjugant cSFJ45]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTTTACACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCTGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACAGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATTGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471