Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NWE22_RS08500 Genome accession   NZ_CP102747
Coordinates   1669640..1670356 (-) Length   238 a.a.
NCBI ID   WP_174845639.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1664640..1675356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS08480 (NWE22_08480) - 1665004..1666230 (-) 1227 WP_277745402.1 cysteine desulfurase -
  NWE22_RS08485 (NWE22_08485) sufD 1666235..1667497 (-) 1263 WP_239604208.1 Fe-S cluster assembly protein SufD -
  NWE22_RS08490 (NWE22_08490) sufC 1667514..1668287 (-) 774 WP_171989104.1 Fe-S cluster assembly ATPase SufC -
  NWE22_RS08495 (NWE22_08495) - 1668459..1669643 (-) 1185 WP_277745403.1 MraY family glycosyltransferase -
  NWE22_RS08500 (NWE22_08500) mecA 1669640..1670356 (-) 717 WP_174845639.1 adaptor protein MecA Regulator
  NWE22_RS08505 (NWE22_08505) - 1670562..1671401 (-) 840 WP_277745747.1 undecaprenyl-diphosphate phosphatase -
  NWE22_RS08510 (NWE22_08510) - 1671677..1673239 (+) 1563 WP_277745404.1 ABC transporter substrate-binding protein/permease -
  NWE22_RS08515 (NWE22_08515) - 1673232..1673975 (+) 744 WP_174845641.1 amino acid ABC transporter ATP-binding protein -
  NWE22_RS08520 (NWE22_08520) - 1674084..1674293 (-) 210 WP_024391394.1 hypothetical protein -
  NWE22_RS08525 (NWE22_08525) - 1674383..1675285 (-) 903 WP_174845642.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27865.52 Da        Isoelectric Point: 4.1340

>NTDB_id=718710 NWE22_RS08500 WP_174845639.1 1669640..1670356(-) (mecA) [Streptococcus parasuis strain SFJ45]
MKVKQISDSTLKITIQLEDLEERGMEIADFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDKVDIFVTKSEM
DQSLNFDEFTDLSELGDVSRMTPDELLKSLERTVRERSTHDSKAVRQLEDAEKEDSDEYQEPYIYYILEFPALIDAVNFV
QTVDYPVEESELYKVEQTYYMTVLINVAERSKQYPEYILSRMLEFTNDTKLTRPFLQEHGILMLGNGAIDELKKVQTV

Nucleotide


Download         Length: 717 bp        

>NTDB_id=718710 NWE22_RS08500 WP_174845639.1 1669640..1670356(-) (mecA) [Streptococcus parasuis strain SFJ45]
ATGAAAGTAAAACAAATAAGTGATTCGACTCTAAAAATCACTATCCAATTAGAGGATTTAGAGGAGCGCGGGATGGAAAT
TGCGGATTTCCTTATCCCTCAAGAAAAGACGGAAGAGTTTTTTTATACAGTATTGGATGAATTGGATTTGCCAATGACTT
TCCGAGAAAGTGGAATGCTTAGTTTTAGAGTTACTCCAAAACCGGATAAAGTGGATATTTTTGTCACAAAATCTGAAATG
GATCAAAGTTTAAATTTTGATGAATTTACAGATTTATCGGAATTAGGCGATGTATCAAGAATGACTCCAGATGAATTGCT
GAAAAGTTTGGAACGTACAGTTCGTGAACGAAGCACGCATGACTCAAAAGCAGTTCGTCAATTAGAAGATGCTGAAAAAG
AAGATAGTGATGAATACCAAGAACCGTATATTTACTATATCTTAGAATTTCCTGCTTTGATTGATGCGGTAAATTTTGTT
CAAACAGTGGATTATCCAGTTGAAGAATCTGAGCTCTACAAAGTGGAGCAAACCTATTATATGACAGTATTGATTAATGT
TGCAGAGCGTTCAAAGCAGTATCCAGAGTATATTCTATCTCGCATGCTTGAATTTACAAACGATACCAAATTGACACGAC
CATTTCTTCAAGAGCACGGAATCTTGATGTTGGGAAATGGGGCCATTGATGAGTTGAAAAAGGTGCAAACGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

49.59

100

0.508
  mecA Streptococcus pneumoniae D39

49.59

100

0.508
  mecA Streptococcus pneumoniae R6

49.59

100

0.508
  mecA Streptococcus pneumoniae TIGR4

49.59

100

0.508
  mecA Streptococcus mutans UA159

47.951

100

0.492
  mecA Streptococcus thermophilus LMD-9

45.714

100

0.471
  mecA Streptococcus thermophilus LMG 18311

45.306

100

0.466