Detailed information NTG0718677

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: NWE22_RS00550
• Genome accession: NZ_CP102747
• Coordinates: 93626..95776 (+)
• Length: 716 a.a.
• NCBI ID: WP_239604429.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain SFJ45
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 88626..100776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE22_RS00510 (NWE22_00510)	-	89286..90632 (+)	1347	WP_239604426.1	GHKL domain-containing protein	-
NWE22_RS00515 (NWE22_00515)	-	91088..91876 (+)	789	WP_239604427.1	ParA family protein	-
NWE22_RS00520 (NWE22_00520)	-	91889..92113 (+)	225	WP_024379520.1	hypothetical protein	-
NWE22_RS00525 (NWE22_00525)	-	92359..92502 (+)	144	WP_153594002.1	bacteriocin	-
NWE22_RS00530 (NWE22_00530)	-	92513..92638 (+)	126	WP_105129977.1	bacteriocin	-
NWE22_RS00535 (NWE22_00535)	-	92817..93005 (+)	189	WP_029176448.1	hypothetical protein	-
NWE22_RS00540 (NWE22_00540)	-	93026..93217 (+)	192	WP_029176447.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
NWE22_RS00545 (NWE22_00545)	-	93245..93454 (+)	210	WP_172089147.1	hypothetical protein	-
NWE22_RS00550 (NWE22_00550)	comA	93626..95776 (+)	2151	WP_239604429.1	peptide cleavage/export ABC transporter ComA	Regulator
NWE22_RS00555 (NWE22_00555)	-	95786..97147 (+)	1362	WP_239604430.1	bacteriocin secretion accessory protein	-
NWE22_RS00560 (NWE22_00560)	-	97496..97837 (+)	342	WP_239604431.1	hypothetical protein	-
NWE22_RS00565 (NWE22_00565)	-	97850..99421 (-)	1572	Protein_91	IS3 family transposase	-
NWE22_RS00570 (NWE22_00570)	-	99496..100155 (-)	660	WP_239604432.1	metal-dependent transcriptional regulator	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80665.65 Da
• Isoelectric Point: 6.9797

>NTDB_id=718677 NWE22_RS00550 WP_239604429.1 93626..95776(+) (comA) [Streptococcus parasuis strain SFJ45]
MRFKKKHYRAQVDTRDCGVASLAMVFGFYGSYYSLATLRELAKTTQEGTTAFGLVKVAEGEGFETRAIRADMTLFDEDII
YPFIAHVVKNGNLMHYYVVTGCDKKSIHIADPDPTVKMIKMPRERFEEEWTGVSLFIAPTPSYKVHKEKKDSLLSFVPIL
ARQRGLILNIVIATLIVTIINIVGSYYLQSIIDTYIPEQVKNTLSIVSVGLVIVYILQQLISYAQEYLLLVLGQRLSIDV
ILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSVFLDVSIIIIVSIVLFSQNINLFFISLLALPIYTVI
ILSFMKPFEKMNQETMESNAVLSSSIIEDINGIETIKSLTSERQRYQKIDKEFIDYLKKSFAYGRAESIQKTLKKLAQLL
LNVAVLWMGANLVMDNKMTLGQLITYNSLLVYFTNPLENIINLQTKLQTAKVANNRLNEVYLVKSEFEEQKTVHDLSHFK
GNLTFNSVSYKYGYGRDVLSDINLTLKAGSKVSFVGISGSGKTTLAKMLVNFFSPSKGEILLDDVNLEDINKESLRRYIN
YLPQQPYVFNGTILDNLLLGAKEGTTQEDISRAVQIAEIKSDIESMPLNYQTELTSDGVGISGGQRQRIALARALLTDSP
VLILDEATSSLDVLTEKKIIDNLMELDKTLIFIAHRLTISERTEHIVVLDKGKIIEEGTHQDLLQKQGFYAHLVNS

Nucleotide

• Length: 2151 bp

>NTDB_id=718677 NWE22_RS00550 WP_239604429.1 93626..95776(+) (comA) [Streptococcus parasuis strain SFJ45]
ATGCGTTTTAAGAAGAAACATTATCGTGCTCAAGTAGATACTAGGGACTGCGGTGTTGCATCTCTAGCAATGGTTTTTGG
TTTCTATGGGTCTTATTACTCATTGGCCACTTTGCGTGAGTTAGCGAAGACTACACAAGAGGGGACAACAGCTTTTGGAT
TGGTCAAAGTTGCTGAAGGTGAAGGATTTGAAACTCGAGCAATCCGTGCAGATATGACTCTTTTTGATGAGGATATCATC
TATCCTTTTATTGCTCATGTAGTCAAAAATGGGAATTTGATGCACTATTATGTCGTAACTGGATGTGATAAAAAGTCAAT
CCATATTGCCGATCCAGATCCGACAGTTAAGATGATTAAGATGCCACGTGAGCGATTTGAAGAGGAGTGGACAGGAGTAT
CTCTTTTTATTGCTCCCACTCCCAGCTATAAGGTTCACAAAGAAAAGAAAGATAGCTTATTGTCTTTTGTCCCTATCCTT
GCTAGACAGAGGGGACTGATATTAAATATTGTCATTGCCACTCTTATAGTGACTATAATCAATATTGTTGGTTCATACTA
TCTACAATCGATTATAGATACCTATATTCCTGAACAGGTAAAAAATACTCTAAGCATTGTGTCAGTTGGATTAGTTATCG
TCTATATTCTTCAACAACTGATTTCATATGCTCAAGAGTACTTATTATTGGTCCTGGGGCAGAGATTATCAATTGATGTT
ATTTTGTCTTATATCAAGCATGTTTTTCACTTGCCGATGTCTTTCTTTGCAACAAGAAGAACAGGGGAAATCGTTTCACG
TTTCACTGATGCTAATTCAATCATCGATGCTTTAGCAAGTACGATTTTATCGGTTTTCTTAGATGTTTCGATTATCATCA
TTGTTTCAATTGTTTTGTTTTCTCAAAACATTAACCTATTTTTCATTAGCTTACTTGCATTGCCAATCTATACCGTGATT
ATCCTATCTTTCATGAAACCATTCGAAAAAATGAATCAAGAAACAATGGAATCTAATGCGGTCCTATCATCTTCAATCAT
TGAAGATATTAACGGCATTGAGACAATCAAGTCCTTAACAAGTGAACGTCAACGTTATCAAAAGATTGATAAGGAATTTA
TTGATTATCTGAAGAAGTCATTTGCTTACGGTAGAGCTGAGAGCATTCAGAAAACGCTAAAAAAATTGGCTCAGTTATTG
CTGAATGTTGCGGTATTATGGATGGGAGCAAATCTTGTTATGGATAATAAGATGACATTAGGTCAGCTTATTACCTATAA
CTCTCTATTGGTTTACTTCACAAACCCTCTGGAAAATATTATTAACCTTCAGACGAAGTTACAAACTGCTAAAGTTGCAA
ATAACCGCCTAAATGAAGTATACCTGGTAAAATCTGAATTTGAAGAGCAAAAAACAGTTCATGATTTGAGCCATTTCAAA
GGGAATCTAACATTCAACAGTGTCAGCTATAAGTATGGATATGGTAGAGATGTTCTTAGTGACATTAATCTCACATTGAA
AGCAGGTAGTAAGGTGTCATTTGTAGGAATTTCAGGTTCAGGAAAAACTACATTGGCCAAGATGCTTGTTAACTTCTTTA
GTCCATCAAAGGGTGAGATTTTATTAGATGATGTGAATCTAGAAGACATTAACAAAGAAAGTCTTCGAAGATATATCAAT
TATCTACCTCAACAACCGTATGTTTTTAATGGTACTATCCTGGATAATCTTTTGCTAGGAGCAAAAGAGGGAACGACTCA
GGAAGATATTTCTAGGGCAGTTCAAATCGCAGAAATCAAGTCCGATATAGAATCTATGCCGTTGAACTATCAAACAGAAT
TAACGTCAGATGGTGTTGGTATTTCAGGAGGTCAGCGTCAGAGGATTGCCTTGGCTAGAGCCTTATTGACGGATTCTCCA
GTATTGATTTTAGATGAGGCAACCAGTAGCTTAGATGTATTGACTGAGAAGAAAATCATAGATAATCTTATGGAATTAGA
TAAGACATTGATTTTCATTGCTCATAGATTAACAATTTCTGAAAGAACGGAGCATATTGTTGTCCTTGATAAAGGTAAAA
TTATTGAAGAAGGAACTCATCAAGATTTGCTACAGAAACAAGGATTTTATGCTCATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (6-141)

• ABC transporter transmembrane region (ABC_membrane) (168-437)

• ABC transporter (ABC_tran) (499-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	81.311	100	0.814
comA	Streptococcus pneumoniae Rx1	81.032	100	0.811
comA	Streptococcus pneumoniae D39	81.032	100	0.811
comA	Streptococcus pneumoniae R6	81.032	100	0.811
comA	Streptococcus mitis SK321	80.753	100	0.809
comA	Streptococcus pneumoniae TIGR4	80.753	100	0.809
comA	Streptococcus gordonii str. Challis substr. CH1	75.314	100	0.754
comA/nlmT	Streptococcus mutans UA159	63.319	100	0.634