Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   IL310_RS04695 Genome accession   NZ_CP117409
Coordinates   479902..481803 (+) Length   633 a.a.
NCBI ID   WP_201248302.1    Uniprot ID   -
Organism   Lactococcus lactis strain LB7     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 474902..486803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IL310_RS04665 (IL310_04670) - 476016..476258 (+) 243 WP_003131476.1 GlsB/YeaQ/YmgE family stress response membrane protein -
  IL310_RS04670 (IL310_04675) amaP 476286..476846 (+) 561 WP_010906186.1 alkaline shock response membrane anchor protein AmaP -
  IL310_RS04675 (IL310_04680) - 476857..477045 (+) 189 WP_012898445.1 DUF2273 domain-containing protein -
  IL310_RS04680 (IL310_04685) - 477066..477572 (+) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  IL310_RS04685 (IL310_04690) rsmB 477771..479045 (+) 1275 WP_201248303.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  IL310_RS04690 (IL310_04695) - 479126..479902 (+) 777 WP_058204010.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  IL310_RS04695 (IL310_04700) pknB 479902..481803 (+) 1902 WP_201248302.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  IL310_RS04700 (IL310_04705) rpsO 481985..482254 (+) 270 WP_015427039.1 30S ribosomal protein S15 -
  IL310_RS04705 (IL310_04710) proC 482333..483121 (-) 789 WP_058203448.1 pyrroline-5-carboxylate reductase -
  IL310_RS04710 (IL310_04715) glmU 483349..484725 (+) 1377 WP_003130798.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  IL310_RS04715 (IL310_04720) - 484830..485414 (+) 585 WP_201248301.1 NUDIX hydrolase -
  IL310_RS04720 (IL310_04725) macP 485407..485685 (+) 279 WP_003130796.1 cell wall synthase accessory phosphoprotein MacP -
  IL310_RS04725 (IL310_04730) - 485717..486397 (+) 681 WP_017864968.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68964.07 Da        Isoelectric Point: 4.7535

>NTDB_id=718008 IL310_RS04695 WP_201248302.1 479902..481803(+) (pknB) [Lactococcus lactis strain LB7]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVGNKNKKSKKGLIIGIIVFLLVVGGATLAWVVSTPSNVKVPNVANMTQSEAESAIKKADLKVGAIRKDSSSDV
AKNKVTRTDPTSRTYVRTGSKVNIYISQGGNSFKMKNYVGKNYQDAKDELVIKYNVSENQITSKTVASKQAAGTVISQTP
KEGDYFDLDGNDQIVLEVSEGAQGVMPEFKNRTWKQVKADLISIGVPEENIILDQQPNTGYSNGENYVYDSNVAAGQSFN
IATQQITLTYLGPYQPTSTESSSTPQSTTTESSSTPQSTTSETSSSPISTPQSTNNSGDSSNNKENSTTTPSS

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=718008 IL310_RS04695 WP_201248302.1 479902..481803(+) (pknB) [Lactococcus lactis strain LB7]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGCGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAGCTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATTAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTCGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAGGCTGCAAGCTCAGAAGTAGGAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGCATTATTGTCTTTCT
TTTAGTTGTTGGTGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAAGTAATGTTAAAGTACCAAATGTTGCTAACATGA
CACAAAGTGAAGCAGAATCGGCAATTAAAAAGGCTGATTTGAAAGTTGGAGCGATTCGCAAAGACTCAAGTTCAGATGTG
GCCAAGAATAAAGTAACCCGTACAGATCCAACATCACGAACATATGTTCGAACAGGAAGCAAGGTAAATATTTATATTTC
TCAAGGTGGTAATTCTTTTAAAATGAAAAATTATGTAGGGAAAAACTATCAAGATGCGAAAGATGAGTTGGTGATTAAAT
ATAATGTTTCTGAGAATCAAATTACCTCTAAAACAGTTGCAAGTAAGCAGGCTGCCGGAACAGTTATAAGTCAAACTCCC
AAAGAGGGTGATTATTTTGACCTTGATGGTAATGATCAAATCGTGTTAGAAGTCTCTGAAGGAGCTCAAGGAGTGATGCC
TGAGTTTAAAAATAGAACTTGGAAACAAGTGAAGGCAGATTTGATTTCCATAGGCGTTCCAGAAGAAAATATTATTTTGG
ATCAGCAACCAAATACCGGATATTCTAATGGTGAAAATTATGTTTATGATTCCAATGTAGCAGCTGGGCAATCATTTAAT
ATTGCTACACAACAAATTACATTGACTTATCTCGGGCCATATCAACCAACCTCAACAGAGAGTTCGTCAACCCCTCAATC
AACAACAACAGAGAGTTCATCAACTCCTCAATCAACAACATCAGAAACCTCGTCGAGTCCTATTAGCACTCCCCAATCAA
CAAATAATAGCGGCGATAGTAGTAATAACAAAGAAAATTCAACAACTACACCAAGTAGTTGA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(505-570)

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(434-499)

Protein kinase domain (Pkinase)

(12-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

50

85.624

0.428
  stkP Streptococcus pneumoniae TIGR4

46.274

91.153

0.422
  stkP Streptococcus pneumoniae D39

46.101

91.153

0.42
  stkP Streptococcus pneumoniae R6

46.101

91.153

0.42
  stkP Streptococcus pneumoniae Rx1

48.052

85.15

0.409
  stkP/pknB Streptococcus salivarius strain HSISS4

49.331

82.622

0.408