Detailed information NTG0071765

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EL269_RS11580
• Genome accession: NZ_AP018935
• Coordinates: 2229016..2230245 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728358.1
• Uniprot ID: A0AAW3HT93
• Organism: Streptococcus agalactiae strain HU-GS5823
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2224016..2235245

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL269_RS11555 (SAGS_2211)	-	2225178..2227757 (+)	2580	WP_000154437.1	YfhO family protein	-
EL269_RS11575 (SAGS_2215)	rlmH	2228336..2228815 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL269_RS11580 (SAGS_2216)	htrA	2229016..2230245 (+)	1230	WP_000728358.1	S1C family serine protease	Regulator
EL269_RS11585 (SAGS_2217)	spo0J	2230343..2231116 (+)	774	WP_000456087.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43118.59 Da
• Isoelectric Point: 9.5271

>NTDB_id=71765 EL269_RS11580 WP_000728358.1 2229016..2230245(+) (htrA) [Streptococcus agalactiae strain HU-GS5823]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVVSPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=71765 EL269_RS11580 WP_000728358.1 2229016..2230245(+) (htrA) [Streptococcus agalactiae strain HU-GS5823]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGTATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.281	97.311	0.548
htrA	Streptococcus pneumoniae TIGR4	54.791	99.511	0.545
htrA	Streptococcus pneumoniae Rx1	54.791	99.511	0.545
htrA	Streptococcus pneumoniae D39	54.791	99.511	0.545
htrA	Streptococcus pneumoniae R6	54.791	99.511	0.545