Detailed information NTG0717460

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: MGGS36055_RS00350
• Genome accession: NZ_CP117286
• Coordinates: 55941..56852 (+)
• Length: 303 a.a.
• NCBI ID: WP_015016522.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 50941..61852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGGS36055_RS00335 (MGGS36055_00134)	purK	51371..52444 (+)	1074	WP_015016519.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
MGGS36055_RS00340 (MGGS36055_00136)	-	52463..54322 (+)	1860	WP_015016520.1	DUF262 domain-containing protein	-
MGGS36055_RS00345 (MGGS36055_00138)	purB	54507..55799 (+)	1293	WP_148848402.1	adenylosuccinate lyase	-
MGGS36055_RS00350 (MGGS36055_00140)	comR	55941..56852 (+)	912	WP_015016522.1	XRE family transcriptional regulator	Regulator
MGGS36055_RS00355 (MGGS36055_00142)	comS	56939..57034 (+)	96	WP_198455558.1	quorum-sensing system DWW-type pheromone	Regulator
MGGS36055_RS00360 (MGGS36055_00144)	-	57138..58271 (+)	1134	WP_022554244.1	ISAs1-like element IS1548 family transposase	-
MGGS36055_RS00370 (MGGS36055_00146)	ruvB	58413..59411 (+)	999	WP_015057190.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
MGGS36055_RS00375 (MGGS36055_00148)	-	59546..59977 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
MGGS36055_RS00380 (MGGS36055_00150)	-	60006..60407 (+)	402	WP_003049089.1	MORN repeat-containing protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35741.28 Da
• Isoelectric Point: 4.5798

>NTDB_id=717460 MGGS36055_RS00350 WP_015016522.1 55941..56852(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEQLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKQRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKIIIDISSLSIKTNKLDNLEKTIAISQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide

• Length: 912 bp

>NTDB_id=717460 MGGS36055_RS00350 WP_015016522.1 55941..56852(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAACAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTAAGTG
AAAACATCAATTTTGGTGTCGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAACAACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAATTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGGCA
AAAATCCAGGATTGGAATAGAATGCCTATACTAAAATTAATAGAATGGAAGTACTTTTTAATAAAACAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAAATAACAGGAGACAAGTATTTGGAAGAGCAATTAATCA
AAGAATGGGAGAAAGATATTTGTGCTTATTAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	82.178	100	0.822
comR	Streptococcus pyogenes MGAS315	54.667	99.01	0.541
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	50.847	97.36	0.495
comR	Streptococcus mutans UA159	49.498	98.68	0.488