Detailed information NTG0717304

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: MGCS36089_RS05640
• Genome accession: NZ_CP117284
• Coordinates: 1112130..1112804 (-)
• Length: 224 a.a.
• NCBI ID: WP_014612304.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1107130..1117804

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS36089_RS05615 (MGCS36089_02274)	-	1107316..1108593 (-)	1278	WP_015017041.1	pyrimidine-nucleoside phosphorylase	-
MGCS36089_RS05620 (MGCS36089_02276)	-	1108580..1109179 (-)	600	WP_015057597.1	class I SAM-dependent methyltransferase	-
MGCS36089_RS05625 (MGCS36089_02278)	coaA	1109447..1110367 (+)	921	WP_084916836.1	type I pantothenate kinase	-
MGCS36089_RS05630 (MGCS36089_02280)	rpsT	1110421..1110669 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
MGCS36089_RS05635 (MGCS36089_02282)	ciaH	1110827..1112137 (-)	1311	WP_014612303.1	sensor histidine kinase	Regulator
MGCS36089_RS05640 (MGCS36089_02284)	ciaR	1112130..1112804 (-)	675	WP_014612304.1	response regulator transcription factor	Regulator
MGCS36089_RS05645 (MGCS36089_02286)	-	1113008..1115545 (-)	2538	WP_084916834.1	M1 family metallopeptidase	-
MGCS36089_RS05650 (MGCS36089_02288)	phoU	1115746..1116399 (-)	654	WP_003057760.1	phosphate signaling complex protein PhoU	-
MGCS36089_RS05655 (MGCS36089_02290)	pstB	1116477..1117235 (-)	759	WP_003057749.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25592.57 Da
• Isoelectric Point: 4.4128

>NTDB_id=717304 MGCS36089_RS05640 WP_014612304.1 1112130..1112804(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGQGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide

• Length: 675 bp

>NTDB_id=717304 MGCS36089_RS05640 WP_014612304.1 1112130..1112804(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACAGGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (5-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	84.163	98.661	0.83
ciaR	Streptococcus pneumoniae D39	84.163	98.661	0.83
ciaR	Streptococcus pneumoniae R6	84.163	98.661	0.83
ciaR	Streptococcus pneumoniae TIGR4	84.163	98.661	0.83
ciaR	Streptococcus mutans UA159	83.71	98.661	0.826
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.326	100	0.388
vicR	Streptococcus mutans UA159	35.443	100	0.375