Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NUJ10_RS00235 Genome accession   NZ_CP102425
Coordinates   47986..50136 (+) Length   716 a.a.
NCBI ID   WP_219285670.1    Uniprot ID   -
Organism   Limosilactobacillus reuteri strain FN041     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 42986..55136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NUJ10_RS00210 (NUJ10_00210) - 43440..44834 (+) 1395 WP_219285666.1 L,D-transpeptidase family protein -
  NUJ10_RS00215 (NUJ10_00215) - 45144..45269 (+) 126 WP_255316889.1 hypothetical protein -
  NUJ10_RS00220 (NUJ10_00220) - 45266..46573 (+) 1308 WP_219285667.1 GHKL domain-containing protein -
  NUJ10_RS00225 (NUJ10_00225) - 46581..47348 (+) 768 WP_219285668.1 LytTR family DNA-binding domain-containing protein -
  NUJ10_RS00230 (NUJ10_00230) - 47551..47709 (+) 159 WP_219285669.1 hypothetical protein -
  NUJ10_RS00235 (NUJ10_00235) comA 47986..50136 (+) 2151 WP_219285670.1 peptide cleavage/export ABC transporter Regulator
  NUJ10_RS00240 (NUJ10_00240) - 50169..50354 (-) 186 WP_219285671.1 hypothetical protein -
  NUJ10_RS00245 (NUJ10_00245) - 50634..51062 (-) 429 WP_219285672.1 OsmC family protein -
  NUJ10_RS00250 (NUJ10_00250) - 51131..52126 (-) 996 WP_219285673.1 D-2-hydroxyacid dehydrogenase -
  NUJ10_RS00255 (NUJ10_00255) - 52128..53315 (-) 1188 WP_219285674.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  NUJ10_RS00260 (NUJ10_00260) - 53820..54041 (+) 222 WP_003669553.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 81135.45 Da        Isoelectric Point: 8.6047

>NTDB_id=716898 NUJ10_RS00235 WP_219285670.1 47986..50136(+) (comA) [Limosilactobacillus reuteri strain FN041]
MKINYPHYVAQVDETDCGVAALAMILHNFGSACPIAKLRDLARTTKQGTTALGLVKAAKYLGLDVIPIQADISLFDDPEI
TYPLIAHVIKDDLLHYCVVFKADQDYIYVADPDPATKVQKMTRDEFDRLWSGVCLLFSPAKGYTPQKEPLAGLTTMFRQL
TNYKKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLAILAGNLLVVYVFNSLFNYLRDVLLTRLDQKLTSQI
SLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSSTIISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVII
IYAFNKRFAKLDQEQLESNAQLSSAIIEDLKGVETLKVLRLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQYG
LVTIILFQGAILVIQDRLSIGTLMAFNALLAFFISPLQNIINLQPKLQEAKVANNRLNEVLQVDTEKSNTNSRDQADLVG
PINIQHVDYSYEYSRPILKDINLQIGCNDKLAIVGLSGSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHY
LPQSPQLFSGTIKDNLLMGLDREVSAEEIDNACKLALIYNNIQKMPLKYETKLDEEATALSGGQKQRLTIARALLTSARV
LIFDESTSSLDPITEKRIVENLLSIKDRTMIFIAHRLSIAKKVNRVVVMRDGKIIEQGTHQELLNHHQEYYNLWNT

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=716898 NUJ10_RS00235 WP_219285670.1 47986..50136(+) (comA) [Limosilactobacillus reuteri strain FN041]
ATGAAAATTAATTATCCTCATTATGTAGCTCAAGTTGATGAAACAGATTGTGGAGTCGCTGCTTTAGCAATGATTTTGCA
CAATTTTGGCTCTGCTTGCCCAATCGCAAAATTACGTGACTTAGCACGGACAACTAAGCAAGGAACTACTGCCTTAGGAC
TTGTAAAAGCAGCGAAATATCTTGGATTAGACGTTATACCCATTCAAGCAGATATATCATTGTTTGATGATCCTGAAATT
ACTTACCCGTTGATCGCACATGTGATTAAGGATGATTTACTTCATTACTGTGTCGTTTTTAAGGCTGATCAAGATTACAT
CTATGTAGCTGATCCAGACCCTGCTACAAAAGTACAAAAAATGACTCGAGATGAATTTGATCGTTTATGGTCAGGTGTAT
GTTTACTTTTTTCGCCTGCTAAGGGATATACGCCACAAAAAGAGCCTTTAGCTGGATTAACGACGATGTTTCGACAATTA
ACTAATTATAAAAAAGATATATCAGGAATTGTTATTGCGGCAATGCTAATTACTTTCATCAGCATCGTCGGTTCATACTA
TCTCCAATTAATTATTGATCGGTTTATTCCCTCGAAAAATATTAATGGCTTAGCGATCCTTGCTGGTAATTTATTAGTAG
TTTATGTGTTTAATTCTCTTTTTAATTATCTGCGGGATGTTCTTTTGACTAGGCTGGATCAAAAACTGACATCACAAATA
AGTCTTAGATATATTCACCATGTTTATCGTCTACCGATGCGATTTTTCTCCACAAGAAAAACGGGAGAAATTACTTCACG
GTTTAATGACATTAATAAGATTATTGATGCCTTATCAAGCACTATTATTTCAATGTTCTTAGACGTTGGCGTAATGGTGA
TTATAGGAATTGTTCTTTCTTTGTATGATCGGTCATTATTTTTAACTACAATTAGTACCATTCCGATTTATGTCATTATC
ATTTATGCCTTTAATAAACGTTTTGCTAAACTTGATCAGGAACAGCTGGAGAGTAATGCTCAATTAAGCTCTGCTATTAT
TGAGGATTTAAAAGGCGTAGAGACGTTGAAAGTACTGCGACTTGAAAATATCCGTTATAAAAATGTTGAAAAGCAATTTG
CGGATTTCTTGCGAAAGAATCTAACATATGTTAAAACTAAATCTTTTCAGGATGCAATTAAAATGTGGATTCAATACGGC
TTAGTAACAATCATTCTTTTTCAAGGGGCAATTTTGGTAATTCAGGACCGATTAAGTATTGGGACCTTGATGGCTTTTAA
TGCGTTATTAGCCTTTTTTATCAGTCCATTGCAAAATATTATTAATCTTCAACCTAAACTCCAAGAAGCTAAAGTAGCGA
ATAATCGATTGAATGAAGTGCTGCAAGTTGACACCGAAAAGTCGAATACAAATTCTCGGGATCAAGCAGATTTGGTAGGG
CCGATAAACATTCAACATGTTGACTATTCATATGAATATAGTCGTCCAATTTTAAAAGATATCAATCTTCAAATTGGTTG
TAATGACAAATTGGCAATTGTAGGGTTGAGCGGTTCTGGTAAATCGACCTTGGCAAAGTTATTAGTTGGCTTTTATTTAC
CTACTCAAGGGCAGATAGAATTTAATCAGCATAAAACAACAGAGATTAATCTTTGCGATATTAGACAATATGTACATTAC
TTACCCCAATCGCCACAATTATTTTCGGGAACAATCAAAGATAACTTGCTAATGGGATTAGACCGGGAAGTATCAGCTGA
AGAAATCGATAATGCATGTAAATTAGCATTAATATATAATAATATTCAAAAGATGCCCTTAAAATATGAAACAAAACTAG
ATGAAGAAGCAACTGCATTATCTGGCGGCCAAAAACAACGCTTGACGATTGCACGGGCACTCCTAACTTCTGCGCGTGTT
TTAATTTTTGATGAATCAACAAGTAGCTTAGATCCAATTACTGAAAAAAGAATCGTTGAAAATTTGCTTAGTATTAAAGA
CCGCACAATGATTTTTATTGCCCACCGCCTTTCAATTGCTAAAAAGGTCAATAGAGTGGTAGTAATGCGCGACGGAAAAA
TCATTGAGCAGGGTACTCACCAGGAACTTTTGAATCATCATCAAGAATACTATAATTTGTGGAATACATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-141)

ABC transporter (ABC_tran)

(498-648)

ABC transporter transmembrane region (ABC_membrane)

(170-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

48.05

100

0.482
  comA Streptococcus pneumoniae TIGR4

47.911

100

0.48
  comA Streptococcus pneumoniae Rx1

47.911

100

0.48
  comA Streptococcus pneumoniae D39

47.911

100

0.48
  comA Streptococcus pneumoniae R6

47.911

100

0.48
  comA Streptococcus mitis SK321

47.632

100

0.478
  comA Streptococcus gordonii str. Challis substr. CH1

46.379

100

0.465
  comA/nlmT Streptococcus mutans UA159

46.003

99.581

0.458