Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NQ504_RS09610 Genome accession   NZ_CP102284
Coordinates   1919908..1920273 (-) Length   121 a.a.
NCBI ID   WP_003692142.1    Uniprot ID   E7FPZ0
Organism   Ligilactobacillus ruminis strain ATCC 25644     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1914908..1925273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQ504_RS09585 (NQ504_09585) - 1915047..1915679 (+) 633 WP_003692136.1 flotillin domain-containing protein -
  NQ504_RS09590 (NQ504_09590) - 1916268..1916747 (+) 480 WP_003692138.1 hypothetical protein -
  NQ504_RS09595 (NQ504_09595) celB 1917138..1918493 (+) 1356 WP_259959980.1 PTS cellobiose transporter subunit IIC -
  NQ504_RS09600 (NQ504_09600) - 1918548..1918793 (-) 246 WP_259959981.1 hypothetical protein -
  NQ504_RS09605 (NQ504_09605) comA 1918810..1919772 (-) 963 WP_225430492.1 ABC transporter transmembrane domain-containing protein Regulator
  NQ504_RS09610 (NQ504_09610) comA 1919908..1920273 (-) 366 WP_003692142.1 cysteine peptidase family C39 domain-containing protein Regulator
  NQ504_RS09615 (NQ504_09615) - 1920286..1921050 (-) 765 WP_003692143.1 LytR/AlgR family response regulator transcription factor -
  NQ504_RS09620 (NQ504_09620) - 1921052..1922302 (-) 1251 WP_003692144.1 GHKL domain-containing protein -
  NQ504_RS09625 (NQ504_09625) - 1922655..1923128 (+) 474 WP_022279904.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -
  NQ504_RS09630 (NQ504_09630) - 1923314..1923484 (+) 171 WP_003692146.1 leucocin A/sakacin P family class II bacteriocin -
  NQ504_RS09635 (NQ504_09635) - 1923514..1923867 (+) 354 WP_003692147.1 bacteriocin immunity protein -
  NQ504_RS09640 (NQ504_09640) - 1924092..1924971 (+) 880 Protein_1846 PTS transporter subunit EIIC -

Sequence

Protein


Download         Length: 121 a.a.        Molecular weight: 13621.69 Da        Isoelectric Point: 5.0875

>NTDB_id=715879 NQ504_RS09610 WP_003692142.1 1919908..1920273(-) (comA) [Ligilactobacillus ruminis strain ATCC 25644]
MQVFKKYYLPQMDENDCGIACLAMILKYYGSNVSLSYLRNLAKTNLEGTTALGLVKAAQELNLKTDAYQTDMALFEQSDF
IAHVIKQATLQHYYLVLGANEDYIQIADPDETVGIKKMPKS

Nucleotide


Download         Length: 366 bp        

>NTDB_id=715879 NQ504_RS09610 WP_003692142.1 1919908..1920273(-) (comA) [Ligilactobacillus ruminis strain ATCC 25644]
GTGCAGGTTTTCAAAAAATACTACCTCCCCCAGATGGATGAAAATGACTGTGGGATTGCTTGCTTAGCCATGATTCTTAA
ATATTATGGCTCAAATGTTTCATTATCGTATTTAAGAAACTTAGCCAAAACTAACTTAGAGGGAACAACTGCTTTAGGCT
TAGTAAAGGCCGCCCAAGAGCTAAATCTTAAGACGGACGCTTACCAAACTGATATGGCGCTATTTGAGCAGTCTGATTTT
ATTGCTCACGTAATCAAACAAGCAACTTTGCAACACTACTACTTAGTTCTTGGCGCTAACGAGGACTACATTCAAATTGC
CGATCCAGATGAAACCGTCGGAATTAAAAAAATGCCTAAAAGTTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(6-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E7FPZ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

51.613

100

0.529
  comA Streptococcus pneumoniae TIGR4

50.806

100

0.521
  comA Streptococcus pneumoniae Rx1

50.806

100

0.521
  comA Streptococcus pneumoniae D39

50.806

100

0.521
  comA Streptococcus mitis SK321

50.806

100

0.521
  comA Streptococcus pneumoniae R6

50.806

100

0.521
  comA Streptococcus gordonii str. Challis substr. CH1

49.194

100

0.504
  comA/nlmT Streptococcus mutans UA159

47.967

100

0.488