Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   NQZ97_RS08125 Genome accession   NZ_CP102136
Coordinates   1663592..1665829 (-) Length   745 a.a.
NCBI ID   WP_257110526.1    Uniprot ID   -
Organism   Streptococcus suis strain M105052_S26     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1658592..1670829
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ97_RS08125 (NQZ97_08125) comEC/celB 1663592..1665829 (-) 2238 WP_257110526.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NQZ97_RS08130 (NQZ97_08130) comEA/celA/cilE 1665813..1666475 (-) 663 WP_256787520.1 helix-hairpin-helix domain-containing protein Machinery gene
  NQZ97_RS08135 (NQZ97_08135) - 1666544..1667290 (-) 747 WP_100664857.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  NQZ97_RS08140 (NQZ97_08140) - 1667439..1668884 (+) 1446 WP_043026933.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  NQZ97_RS08145 (NQZ97_08145) - 1669350..1670135 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83849.68 Da        Isoelectric Point: 7.2044

>NTDB_id=714642 NQZ97_RS08125 WP_257110526.1 1663592..1665829(-) (comEC/celB) [Streptococcus suis strain M105052_S26]
MSRSIKLPSQPIHLAILAVATYFAVHSFSLLTMGLLSLLLLVFGFRQGKTVFLKTLPLLALCGLFFGCQKVQWERADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQGEQAYFQKLTGLAQLEVEAEVSLPAGQRNFKGFDYQGYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGILTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPILMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPLVKMTWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEEWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HVGDVLEVAKQVQIGQIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDAYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDNRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=714642 NQZ97_RS08125 WP_257110526.1 1663592..1665829(-) (comEC/celB) [Streptococcus suis strain M105052_S26]
ATGTCACGGTCGATTAAGCTCCCCAGCCAGCCCATCCACCTAGCCATCTTAGCGGTGGCGACCTACTTTGCAGTCCACTC
GTTTTCCCTCTTGACAATGGGCCTGCTCAGTTTGTTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACACTGCCGCTTCTAGCCTTGTGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGATCAGTCAGCC
CCAGAGCAAGTGACAACTGTGCAGGTCATTCCAGATACCATTGAAGTAAACGGGGACAGCTTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTGTTTTACAAATTAGCCAGTCAGGGGGAGCAGGCTTATTTTCAAAAACTGACAGGTCTGG
CTCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTACCAGGGCTACCTG
AAAACACAGGGTATTTATCGGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAGGCTTTGGTTTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGAGCTGGATAGTGATTTTGATCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTTTTC
GCCCTGTCTGGTATGCAAGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTACAAATTCCCTTTTCCATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCTTTGG
TTCAAAAAATTCTGGGTAATCTGGGCTTGCGGAAGCTGGATAATTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGTATCTTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAAGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGATTCTCATGACCTATTTCTATG
CCTTCCAGCCTTTGTCTATCCTCTTGACTTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTCCTCTCACCCTTGGTCAAGATGACCTGGGTCAACGGATTTTTCGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAGAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCTTGATTGATGTGGGCGGTCGGGTCGATTTCGCGGCTAAGGAGGAGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACCTTGATTCCTTATCTGCACAGTCGGGGCGTGGACAGGATTGATAGCTTGGTTCTGACCCATACCGACGCAGAT
CATGTGGGTGATGTGCTGGAAGTGGCGAAGCAAGTCCAGATTGGTCAGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTCCCAGTCCATGTGGTCAAAGTGGGTGACCGCTTGCCGATTTTTGACG
CCTATCTGGAAGTCCTCTATCCAGATGGGACAGGCGACGGTGGTAATAACGACTCTATTGTTCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAATAACCGCTACAAGCATCCCCATCAAGAAACCTTGGAACGATTTGACAATCGGAATATCCAA
GTCTATCGAACTGATCAGCAGGGCGCCATTCGCTTTCGAGGTTGGAGGGAGTGGCGAATTGAAACGGTGAGGGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(28-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.24

99.732

0.541
  comEC/celB Streptococcus mitis NCTC 12261

53.146

100

0.533
  comEC/celB Streptococcus pneumoniae TIGR4

52.446

98.792

0.518
  comEC/celB Streptococcus pneumoniae Rx1

52.174

98.792

0.515
  comEC/celB Streptococcus pneumoniae D39

52.174

98.792

0.515
  comEC/celB Streptococcus pneumoniae R6

52.174

98.792

0.515
  comEC Lactococcus lactis subsp. cremoris KW2

49.732

100

0.498