Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   NQZ98_RS02550 Genome accession   NZ_CP102135
Coordinates   492721..494715 (+) Length   664 a.a.
NCBI ID   WP_024395773.1    Uniprot ID   A0A822VZF9
Organism   Streptococcus suis strain M106471_S40     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 487721..499715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ98_RS02535 (NQZ98_02535) fmt 489708..490646 (+) 939 WP_024400106.1 methionyl-tRNA formyltransferase -
  NQZ98_RS02540 (NQZ98_02540) rsmB 490633..491946 (+) 1314 WP_079269702.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NQZ98_RS02545 (NQZ98_02545) - 491984..492721 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NQZ98_RS02550 (NQZ98_02550) stkP 492721..494715 (+) 1995 WP_024395773.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NQZ98_RS02555 (NQZ98_02555) liaF 495040..495699 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  NQZ98_RS02560 (NQZ98_02560) - 495696..496712 (+) 1017 WP_024388026.1 sensor histidine kinase -
  NQZ98_RS02565 (NQZ98_02565) - 496684..497325 (+) 642 WP_002937025.1 response regulator transcription factor -
  NQZ98_RS02570 (NQZ98_02570) - 497375..498775 (+) 1401 WP_024389590.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NQZ98_RS02575 (NQZ98_02575) - 498777..499148 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71438.01 Da        Isoelectric Point: 6.3011

>NTDB_id=714568 NQZ98_RS02550 WP_024395773.1 492721..494715(+) (stkP) [Streptococcus suis strain M106471_S40]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIATGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYISKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQALGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=714568 NQZ98_RS02550 WP_024395773.1 492721..494715(+) (stkP) [Streptococcus suis strain M106471_S40]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGCATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTTCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGTATTCCCTATGATG
GAGACAGTGCTGTGACGATTGCTCTTCAGCATTTCCAAAAACCTCTTCCATCGGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCAAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACGGAT
AAGGGGCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGACTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTGTCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGTTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTCGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCAAAAATTACCCTTTACATTTCCAAAGGAGTAGCGCCACAAGT
TGTGCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCCGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCGCTAGGCGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGCACCAGTAGCGATTCCTCAACAGGAAGTTCCACCAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(440-501)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(574-638)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A822VZF9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.786

97.289

0.514
  stkP Streptococcus pneumoniae D39

52.632

97.289

0.512
  stkP Streptococcus pneumoniae R6

52.632

97.289

0.512
  stkP Streptococcus pneumoniae Rx1

52.477

97.289

0.511
  stkP/pknB Streptococcus salivarius strain HSISS4

52.479

88.102

0.462
  pknB Streptococcus mutans UA159

54.766

80.572

0.441