Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NL422_RS02965 Genome accession   NZ_CP116931
Coordinates   487431..488555 (+) Length   374 a.a.
NCBI ID   WP_001551734.1    Uniprot ID   -
Organism   Escherichia coli strain MLI106K1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 482431..493555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL422_RS02940 (NL422_002940) mscL 482557..482967 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  NL422_RS02945 (NL422_002945) trkA 483097..484473 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  NL422_RS02950 (NL422_002950) rsmB 484495..485784 (-) 1290 WP_001551736.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NL422_RS02955 (NL422_002955) fmt 485830..486777 (-) 948 WP_000004443.1 methionyl-tRNA formyltransferase -
  NL422_RS02960 (NL422_002960) def 486792..487301 (-) 510 WP_000114986.1 peptide deformylase -
  NL422_RS02965 (NL422_002965) dprA 487431..488555 (+) 1125 WP_001551734.1 DNA-protecting protein DprA Machinery gene
  NL422_RS02970 (NL422_002970) smg 488527..489000 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  NL422_RS02975 (NL422_002975) yrdD 489029..489571 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  NL422_RS02980 (NL422_002980) tsaC 489576..490148 (+) 573 WP_001551733.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  NL422_RS02985 (NL422_002985) aroE 490153..490971 (+) 819 WP_001551732.1 shikimate dehydrogenase -
  NL422_RS02990 (NL422_002990) yrdB 490968..491225 (+) 258 WP_001070567.1 DUF1488 domain-containing protein -
  NL422_RS02995 (NL422_002995) yrdA 491201..491755 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  NL422_RS03000 (NL422_003000) - 491784..492020 (+) 237 WP_136511987.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40934.87 Da        Isoelectric Point: 6.3848

>NTDB_id=714514 NL422_RS02965 WP_001551734.1 487431..488555(+) (dprA) [Escherichia coli strain MLI106K1]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVAGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=714514 NL422_RS02965 WP_001551734.1 487431..488555(+) (dprA) [Escherichia coli strain MLI106K1]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGCAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTAGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.387

82.888

0.401
  dprA Vibrio cholerae strain A1552

48.387

82.888

0.401
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396
  dprA Legionella pneumophila strain ERS1305867

43.363

90.642

0.393