Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NQZ84_RS00355 Genome accession   NZ_CP102094
Coordinates   59971..60870 (+) Length   299 a.a.
NCBI ID   WP_044677095.1    Uniprot ID   A0A0Z8GJ76
Organism   Streptococcus suis strain 12RC1     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 54971..65870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS00330 (NQZ84_00330) - 55619..56362 (+) 744 WP_024389672.1 ABC transporter permease -
  NQZ84_RS00335 (NQZ84_00335) - 56414..56587 (+) 174 WP_162840697.1 hypothetical protein -
  NQZ84_RS00340 (NQZ84_00340) - 56713..57981 (+) 1269 WP_053042400.1 MerR family transcriptional regulator -
  NQZ84_RS00345 (NQZ84_00345) ruvB 58175..59176 (+) 1002 WP_044677096.1 Holliday junction branch migration DNA helicase RuvB -
  NQZ84_RS00350 (NQZ84_00350) - 59244..59867 (+) 624 WP_024414287.1 HAD-IA family hydrolase -
  NQZ84_RS00355 (NQZ84_00355) comR 59971..60870 (+) 900 WP_044677095.1 helix-turn-helix domain-containing protein Regulator
  NQZ84_RS00360 (NQZ84_00360) - 61078..62298 (+) 1221 WP_044670228.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  NQZ84_RS00365 (NQZ84_00365) - 62489..64012 (+) 1524 WP_044769565.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35247.03 Da        Isoelectric Point: 4.4353

>NTDB_id=714275 NQZ84_RS00355 WP_044677095.1 59971..60870(+) (comR) [Streptococcus suis strain 12RC1]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDWDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=714275 NQZ84_RS00355 WP_044677095.1 59971..60870(+) (comR) [Streptococcus suis strain 12RC1]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAACTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTGTCCTTGCCAGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGACGCTATCATGACGGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTCCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTGTCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATTGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8GJ76

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

93.98

100

0.94
  comR Streptococcus suis 05ZYH33

93.98

100

0.94
  comR Streptococcus suis D9

59.801

100

0.602
  comR Streptococcus mutans UA159

45.151

100

0.452
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.801

97.324

0.368
  comR Streptococcus pyogenes MGAS315

37.037

99.331

0.368