Detailed information
Bioinformatically predicted
Overview
| Name | comYD | Type | Machinery gene |
| Locus tag | NQD66_RS01090 | Genome accession | NZ_CP101995 |
| Coordinates | 188980..189408 (+) | Length | 142 a.a. |
| NCBI ID | WP_000793381.1 | Uniprot ID | A0A8B4RCN7 |
| Organism | Streptococcus agalactiae strain BCJB2983 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 190269..235949 | 188980..189408 | flank | 861 |
Gene organization within MGE regions
Location: 188980..235949
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NQD66_RS01090 (NQD66_01090) | comYD | 188980..189408 (+) | 429 | WP_000793381.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| NQD66_RS01095 (NQD66_01095) | comGE | 189380..189679 (+) | 300 | WP_001867089.1 | competence type IV pilus minor pilin ComGE | - |
| NQD66_RS01100 (NQD66_01100) | comGF | 189633..190094 (+) | 462 | WP_001874060.1 | competence type IV pilus minor pilin ComGF | - |
| NQD66_RS01105 (NQD66_01105) | comGG | 190072..190443 (+) | 372 | WP_000601104.1 | competence type IV pilus minor pilin ComGG | - |
| NQD66_RS01110 (NQD66_01110) | comYH | 190558..191532 (+) | 975 | WP_001008570.1 | class I SAM-dependent methyltransferase | Machinery gene |
| NQD66_RS01115 (NQD66_01115) | - | 191564..192757 (+) | 1194 | WP_000047535.1 | acetate kinase | - |
| NQD66_RS01120 (NQD66_01120) | - | 192908..193114 (+) | 207 | WP_000798242.1 | helix-turn-helix transcriptional regulator | - |
| NQD66_RS01125 (NQD66_01125) | - | 193173..193310 (+) | 138 | WP_001867090.1 | hypothetical protein | - |
| NQD66_RS01130 (NQD66_01130) | - | 193351..193806 (+) | 456 | WP_000905674.1 | hypothetical protein | - |
| NQD66_RS01135 (NQD66_01135) | - | 193875..194540 (+) | 666 | WP_000008111.1 | CPBP family intramembrane glutamic endopeptidase | - |
| NQD66_RS01140 (NQD66_01140) | proC | 194561..195331 (-) | 771 | WP_001867096.1 | pyrroline-5-carboxylate reductase | - |
| NQD66_RS01145 (NQD66_01145) | pepA | 195401..196468 (-) | 1068 | WP_001281321.1 | glutamyl aminopeptidase | - |
| NQD66_RS01150 (NQD66_01150) | - | 196653..196892 (-) | 240 | WP_000660181.1 | hypothetical protein | - |
| NQD66_RS01155 (NQD66_01155) | - | 197053..197337 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| NQD66_RS01160 (NQD66_01160) | - | 197334..197657 (+) | 324 | WP_000601792.1 | thioredoxin family protein | - |
| NQD66_RS01165 (NQD66_01165) | ytpR | 197690..198316 (+) | 627 | WP_000578331.1 | YtpR family tRNA-binding protein | - |
| NQD66_RS01170 (NQD66_01170) | - | 198370..199086 (-) | 717 | WP_000186183.1 | class I SAM-dependent methyltransferase | - |
| NQD66_RS01175 (NQD66_01175) | ssbA | 199167..199562 (+) | 396 | WP_000282450.1 | single-stranded DNA-binding protein | Machinery gene |
| NQD66_RS01180 (NQD66_01180) | - | 199685..200329 (+) | 645 | WP_000416612.1 | HAD family phosphatase | - |
| NQD66_RS01185 (NQD66_01185) | - | 200356..202101 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| NQD66_RS01190 (NQD66_01190) | - | 202082..202822 (+) | 741 | WP_000697630.1 | LytTR family DNA-binding domain-containing protein | - |
| NQD66_RS01195 (NQD66_01195) | - | 202992..203447 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| NQD66_RS01200 (NQD66_01200) | lrgB | 203449..204177 (+) | 729 | WP_000421727.1 | antiholin-like protein LrgB | - |
| NQD66_RS01205 (NQD66_01205) | - | 204420..206048 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| NQD66_RS01210 (NQD66_01210) | - | 206161..207138 (+) | 978 | WP_000680644.1 | ABC transporter permease | - |
| NQD66_RS01215 (NQD66_01215) | - | 207135..207956 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| NQD66_RS01220 (NQD66_01220) | - | 207968..208771 (+) | 804 | WP_000140979.1 | ABC transporter ATP-binding protein | - |
| NQD66_RS01225 (NQD66_01225) | - | 208755..209381 (+) | 627 | WP_000171304.1 | ABC transporter ATP-binding protein | - |
| NQD66_RS01230 (NQD66_01230) | treP | 209663..211693 (+) | 2031 | WP_000434610.1 | PTS system trehalose-specific EIIBC component | - |
| NQD66_RS01235 (NQD66_01235) | treC | 211915..213540 (+) | 1626 | WP_000151014.1 | alpha,alpha-phosphotrehalase | - |
| NQD66_RS01240 (NQD66_01240) | - | 213760..215796 (+) | 2037 | WP_000228178.1 | BglG family transcription antiterminator | - |
| NQD66_RS01245 (NQD66_01245) | - | 215799..216083 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| NQD66_RS01250 (NQD66_01250) | - | 216096..217451 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| NQD66_RS01255 (NQD66_01255) | - | 217454..218311 (+) | 858 | WP_000203492.1 | transketolase | - |
| NQD66_RS01260 (NQD66_01260) | - | 218308..219237 (+) | 930 | WP_001203828.1 | transketolase family protein | - |
| NQD66_RS01265 (NQD66_01265) | - | 219346..220605 (+) | 1260 | WP_001203074.1 | ferric reductase-like transmembrane domain-containing protein | - |
| NQD66_RS01270 (NQD66_01270) | rpsO | 220693..220962 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| NQD66_RS01275 (NQD66_01275) | pnp | 221343..223472 (+) | 2130 | WP_000043857.1 | polyribonucleotide nucleotidyltransferase | - |
| NQD66_RS01280 (NQD66_01280) | - | 223474..224226 (+) | 753 | WP_000204780.1 | SseB family protein | - |
| NQD66_RS01285 (NQD66_01285) | cysE | 224235..224819 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| NQD66_RS01290 (NQD66_01290) | - | 224829..225011 (+) | 183 | WP_000656477.1 | hypothetical protein | - |
| NQD66_RS01295 (NQD66_01295) | cysS | 225008..226351 (+) | 1344 | WP_000591129.1 | cysteine--tRNA ligase | - |
| NQD66_RS01300 (NQD66_01300) | - | 226344..226730 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| NQD66_RS01305 (NQD66_01305) | rlmB | 226833..227588 (+) | 756 | WP_000178023.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| NQD66_RS01310 (NQD66_01310) | - | 227585..228103 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| NQD66_RS01315 (NQD66_01315) | - | 228196..229056 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| NQD66_RS01320 (NQD66_01320) | - | 229594..229713 (+) | 120 | Protein_207 | helix-turn-helix transcriptional regulator | - |
| NQD66_RS01325 (NQD66_01325) | - | 230031..231197 (-) | 1167 | WP_000160598.1 | IS30-like element ISSag9 family transposase | - |
| NQD66_RS01330 (NQD66_01330) | rplM | 231498..231944 (+) | 447 | WP_001867156.1 | 50S ribosomal protein L13 | - |
| NQD66_RS01335 (NQD66_01335) | rpsI | 231965..232357 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| NQD66_RS01340 (NQD66_01340) | - | 232503..233657 (-) | 1155 | WP_000110711.1 | site-specific integrase | - |
| NQD66_RS01345 (NQD66_01345) | - | 233712..234230 (-) | 519 | WP_000181342.1 | helix-turn-helix domain-containing protein | - |
| NQD66_RS01350 (NQD66_01350) | - | 234377..234661 (+) | 285 | WP_001287945.1 | hypothetical protein | - |
| NQD66_RS01355 (NQD66_01355) | - | 234673..235527 (+) | 855 | WP_000005759.1 | phage replisome organizer N-terminal domain-containing protein | - |
| NQD66_RS01360 (NQD66_01360) | - | 235538..235828 (+) | 291 | WP_000158581.1 | DUF5962 family protein | - |
Sequence
Protein
Download Length: 142 a.a. Molecular weight: 16493.15 Da Isoelectric Point: 10.0345
>NTDB_id=713945 NQD66_RS01090 WP_000793381.1 188980..189408(+) (comYD) [Streptococcus agalactiae strain BCJB2983]
MKNLLLKCKDKKVKAFTLLESLIVLSVVAFMTLVFSTSFNNIFRQVEETIFFISFEHLYRDTQKLSAFGQKKQTLTISHN
YLENTYERLYLPKTVKVVKSDTLAFDANGGNSSLAKIQFECYRKTVTYQLYIGSGNYRKKEN
MKNLLLKCKDKKVKAFTLLESLIVLSVVAFMTLVFSTSFNNIFRQVEETIFFISFEHLYRDTQKLSAFGQKKQTLTISHN
YLENTYERLYLPKTVKVVKSDTLAFDANGGNSSLAKIQFECYRKTVTYQLYIGSGNYRKKEN
Nucleotide
Download Length: 429 bp
>NTDB_id=713945 NQD66_RS01090 WP_000793381.1 188980..189408(+) (comYD) [Streptococcus agalactiae strain BCJB2983]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAGAGCCTTATTGTATTATCAGT
AGTGGCATTTATGACGTTAGTATTTTCAACATCATTTAATAATATTTTTAGGCAGGTTGAAGAAACAATTTTCTTCATAT
CCTTTGAACATCTTTATAGAGATACTCAGAAATTGAGTGCATTTGGTCAGAAGAAACAAACCCTTACAATCTCTCATAAT
TATCTCGAAAATACTTATGAGAGACTTTATTTACCTAAAACTGTAAAAGTAGTCAAAAGTGACACACTTGCATTTGACGC
TAATGGAGGGAATTCAAGCTTGGCAAAAATTCAATTTGAATGTTATAGAAAAACTGTTACGTATCAATTATATATAGGAA
GTGGTAATTATCGTAAGAAAGAAAATTAG
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAGAGCCTTATTGTATTATCAGT
AGTGGCATTTATGACGTTAGTATTTTCAACATCATTTAATAATATTTTTAGGCAGGTTGAAGAAACAATTTTCTTCATAT
CCTTTGAACATCTTTATAGAGATACTCAGAAATTGAGTGCATTTGGTCAGAAGAAACAAACCCTTACAATCTCTCATAAT
TATCTCGAAAATACTTATGAGAGACTTTATTTACCTAAAACTGTAAAAGTAGTCAAAAGTGACACACTTGCATTTGACGC
TAATGGAGGGAATTCAAGCTTGGCAAAAATTCAATTTGAATGTTATAGAAAAACTGTTACGTATCAATTATATATAGGAA
GTGGTAATTATCGTAAGAAAGAAAATTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYD | Streptococcus mutans UA140 |
52.273 |
92.958 |
0.486 |
| comYD | Streptococcus mutans UA159 |
52.273 |
92.958 |
0.486 |
| comYD | Streptococcus gordonii str. Challis substr. CH1 |
43.662 |
100 |
0.437 |
| comGD/cglD | Streptococcus mitis NCTC 12261 |
41.045 |
94.366 |
0.387 |
| comGD/cglD | Streptococcus pneumoniae TIGR4 |
43.307 |
89.437 |
0.387 |
| comGD/cglD | Streptococcus mitis SK321 |
43.307 |
89.437 |
0.387 |
| comGD/cglD | Streptococcus pneumoniae Rx1 |
42.52 |
89.437 |
0.38 |
| comGD/cglD | Streptococcus pneumoniae D39 |
42.52 |
89.437 |
0.38 |
| comGD/cglD | Streptococcus pneumoniae R6 |
42.52 |
89.437 |
0.38 |