Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   NPS17_RS09050 Genome accession   NZ_CP101985
Coordinates   1902825..1903856 (-) Length   343 a.a.
NCBI ID   WP_258969313.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1897825..1908856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS09010 (NPS17_09010) - 1898003..1898248 (-) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  NPS17_RS09015 (NPS17_09015) - 1898801..1900000 (-) 1200 WP_002265895.1 acetate kinase -
  NPS17_RS09020 (NPS17_09020) comYH 1900059..1901012 (-) 954 WP_019317550.1 class I SAM-dependent methyltransferase Machinery gene
  NPS17_RS09025 (NPS17_09025) comYG 1901067..1901456 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  NPS17_RS09030 (NPS17_09030) comYF 1901434..1901868 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  NPS17_RS09035 (NPS17_09035) comYE 1901855..1902148 (-) 294 WP_258968995.1 competence type IV pilus minor pilin ComGE Machinery gene
  NPS17_RS09040 (NPS17_09040) comYD 1902120..1902524 (-) 405 WP_168742475.1 competence type IV pilus minor pilin ComGD Machinery gene
  NPS17_RS09045 (NPS17_09045) comYC 1902511..1902825 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  NPS17_RS09050 (NPS17_09050) comYB 1902825..1903856 (-) 1032 WP_258969313.1 competence type IV pilus assembly protein ComGB Machinery gene
  NPS17_RS09055 (NPS17_09055) comYA 1903792..1904733 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  NPS17_RS09060 (NPS17_09060) - 1904864..1905247 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39872.51 Da        Isoelectric Point: 9.5151

>NTDB_id=713608 NPS17_RS09050 WP_258969313.1 1902825..1903856(-) (comYB) [Streptococcus mutans strain COCC33-14R]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFSGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEEIWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=713608 NPS17_RS09050 WP_258969313.1 1902825..1903856(-) (comYB) [Streptococcus mutans strain COCC33-14R]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTTCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAATATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

99.417

100

0.994
  comYB Streptococcus mutans UA140

99.125

100

0.991
  comYB Streptococcus gordonii str. Challis substr. CH1

59.767

100

0.598
  comGB/cglB Streptococcus mitis NCTC 12261

58.112

98.834

0.574
  comGB/cglB Streptococcus mitis SK321

56.25

97.959

0.551
  comGB/cglB Streptococcus pneumoniae Rx1

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae D39

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae R6

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae TIGR4

55.655

97.959

0.545
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507