Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   NPS18_RS07010 Genome accession   NZ_CP101984
Coordinates   1447445..1448152 (-) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA-159     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1442445..1453152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS06995 (NPS18_06995) rnc 1444498..1445193 (-) 696 WP_002262927.1 ribonuclease III -
  NPS18_RS07000 (NPS18_07000) vicX 1445300..1446103 (-) 804 WP_002262928.1 MBL fold metallo-hydrolase Regulator
  NPS18_RS07005 (NPS18_07005) vicK 1446100..1447452 (-) 1353 WP_002262929.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NPS18_RS07010 (NPS18_07010) vicR 1447445..1448152 (-) 708 WP_002262930.1 response regulator YycF Regulator
  NPS18_RS07015 (NPS18_07015) - 1448505..1449287 (+) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  NPS18_RS07020 (NPS18_07020) - 1449284..1450096 (+) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  NPS18_RS07025 (NPS18_07025) - 1450114..1450818 (+) 705 WP_002262933.1 amino acid ABC transporter permease -
  NPS18_RS07030 (NPS18_07030) - 1450833..1451483 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  NPS18_RS07035 (NPS18_07035) endA 1451551..1452432 (-) 882 WP_002262935.1 DNA/RNA non-specific endonuclease Machinery gene
  NPS18_RS07040 (NPS18_07040) - 1452474..1452662 (-) 189 WP_002262936.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=713509 NPS18_RS07010 WP_002262930.1 1447445..1448152(-) (vicR) [Streptococcus mutans strain UA-159]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=713509 NPS18_RS07010 WP_002262930.1 1447445..1448152(-) (vicR) [Streptococcus mutans strain UA-159]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGACTTGATTATATTGGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTTAGAAAAAACAGCCATGTTCCAATTATTATGTTATCAGCT
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGTGCTGATGATTATGTGACTAAACCTTTTTCTAATCGTGA
ATTACTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCCGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATCTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAGTTA
ACTCACCGTGAGTTTGAGTTGTTGCATCACTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTTACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTATTACATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451