Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NPS18_RS00220 Genome accession   NZ_CP101984
Coordinates   30970..31551 (+) Length   193 a.a.
NCBI ID   WP_002263134.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA-159     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 25970..36551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS00195 (NPS18_00195) - 26309..27277 (+) 969 WP_002263139.1 ribose-phosphate diphosphokinase -
  NPS18_RS00200 (NPS18_00200) - 27366..28541 (+) 1176 WP_002263138.1 pyridoxal phosphate-dependent aminotransferase -
  NPS18_RS00205 (NPS18_00205) recO 28531..29286 (+) 756 WP_002263137.1 DNA repair protein RecO -
  NPS18_RS00210 (NPS18_00210) plsX 29494..30492 (+) 999 WP_002263136.1 phosphate acyltransferase PlsX -
  NPS18_RS00215 (NPS18_00215) - 30494..30742 (+) 249 WP_002263135.1 acyl carrier protein -
  NPS18_RS00220 (NPS18_00220) comA 30970..31551 (+) 582 WP_002263134.1 ATP-binding cassette domain-containing protein Regulator
  NPS18_RS00225 (NPS18_00225) purC 31674..32381 (+) 708 WP_002263133.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  NPS18_RS00230 (NPS18_00230) - 32391..36116 (+) 3726 WP_002263132.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21388.42 Da        Isoelectric Point: 4.8930

>NTDB_id=713473 NPS18_RS00220 WP_002263134.1 30970..31551(+) (comA) [Streptococcus mutans strain UA-159]
MGKSGSGKTTLAKILAGYYTVSSGDSFLDGEKINYSQLRQLVTYVPQQSYVFTGTILDNLLLGAEEEVTDDRLMEVCSIA
EILDNIKAMPLGFQTQISEDGGLSGGQKQRLAIARALLTRQPVLIFDEATSGLDRDTEEKVIANLSKLERTIIFIAHRGS
VSYYADRIVEIDSGEKIKDRINHRPFSFLMMTL

Nucleotide


Download         Length: 582 bp        

>NTDB_id=713473 NPS18_RS00220 WP_002263134.1 30970..31551(+) (comA) [Streptococcus mutans strain UA-159]
ATGGGGAAAAGTGGTTCTGGAAAGACAACTTTGGCAAAAATTCTTGCAGGCTATTATACTGTTAGTAGCGGTGACTCTTT
CTTAGATGGAGAAAAGATAAATTATTCCCAGCTGCGCCAATTAGTAACTTATGTGCCACAGCAGTCTTATGTTTTTACAG
GAACAATCTTAGATAATCTGCTTCTTGGTGCTGAAGAGGAAGTAACGGATGATCGCTTAATGGAAGTTTGTTCAATTGCT
GAAATTTTAGACAATATCAAGGCAATGCCTTTAGGTTTTCAAACACAGATTTCAGAAGACGGCGGTTTATCTGGTGGTCA
AAAACAGCGTTTAGCTATTGCACGTGCTCTCTTAACCAGACAGCCTGTGTTGATTTTTGATGAGGCAACTAGTGGTTTAG
ATCGTGATACCGAAGAAAAAGTTATTGCCAATTTATCTAAATTGGAGCGCACGATTATTTTTATTGCTCACCGAGGCAGT
GTTTCTTATTATGCTGATCGAATTGTTGAGATTGACTCTGGAGAGAAAATTAAGGATAGAATAAATCATCGTCCTTTCTC
ATTTTTGATGATGACTCTTTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

50.802

96.891

0.492
  comA Streptococcus gordonii str. Challis substr. CH1

51.099

94.301

0.482
  comA/nlmT Streptococcus mutans UA159

49.468

97.409

0.482
  comA Streptococcus pneumoniae D39

49.18

94.819

0.466
  comA Streptococcus pneumoniae Rx1

49.18

94.819

0.466
  comA Streptococcus pneumoniae R6

49.18

94.819

0.466
  comA Streptococcus mitis SK321

48.087

94.819

0.456
  comA Streptococcus pneumoniae TIGR4

48.087

94.819

0.456