Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J62_RS03690 Genome accession   NZ_AP018779
Coordinates   727901..729121 (+) Length   406 a.a.
NCBI ID   WP_110432058.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-III-8 isolate 10H15     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 722901..734121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J62_RS03670 (CHBNIII8_06970) corC 723865..724764 (-) 900 WP_110432054.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J62_RS03675 (CHBNIII8_06980) ampD 725396..725950 (-) 555 WP_110432055.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J62_RS03680 (CHBNIII8_06990) pilA 726064..726513 (+) 450 WP_110432056.1 prepilin peptidase-dependent pilin Machinery gene
  K6J62_RS03685 (CHBNIII8_07000) pilB 726510..727904 (+) 1395 WP_110432057.1 GspE/PulE family protein Machinery gene
  K6J62_RS03690 (CHBNIII8_07010) pilC 727901..729121 (+) 1221 WP_110432058.1 type II secretion system F family protein Machinery gene
  K6J62_RS03695 (CHBNIII8_07020) pilD 729118..729810 (+) 693 WP_110432059.1 A24 family peptidase Machinery gene
  K6J62_RS03700 (CHBNIII8_07030) rho 729864..731126 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  K6J62_RS03705 (CHBNIII8_07040) metJ 731373..731690 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J62_RS03710 (CHBNIII8_07050) cueR 731704..732090 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  K6J62_RS03715 (CHBNIII8_07060) - 732167..732373 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J62_RS03720 (CHBNIII8_07070) - 732447..732653 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J62_RS03725 (CHBNIII8_07080) - 732727..732933 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46235.51 Da        Isoelectric Point: 9.7212

>NTDB_id=71253 K6J62_RS03690 WP_110432058.1 727901..729121(+) (pilC) [Haemophilus influenzae strain CHBN-III-8 isolate 10H15]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISCGLTHIKLQQNWQFGTKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIEAGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=71253 K6J62_RS03690 WP_110432058.1 727901..729121(+) (pilC) [Haemophilus influenzae strain CHBN-III-8 isolate 10H15]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCTGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGACAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGCACTCAAATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCTATTGAAGCTGGTTT
AGCATTTTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGCAAACTAGCCGTAGTTTGTAAAAAAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATCATGTTGTACCCCTCAATGGTGTTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCGACAATCACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGAAGCCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCAGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.276

100

0.983
  pilC Haemophilus influenzae Rd KW20

98.03

100

0.98
  pilC Glaesserella parasuis strain SC1401

38.653

98.768

0.382

Multiple sequence alignment