Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NPA45_RS11575 Genome accession   NZ_CP101845
Coordinates   2435440..2437632 (-) Length   730 a.a.
NCBI ID   WP_309215864.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus strain Fmb14     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2430440..2442632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPA45_RS11555 - 2430662..2431744 (+) 1083 WP_309215860.1 aldo/keto reductase -
  NPA45_RS11560 - 2432043..2433398 (-) 1356 WP_309215861.1 threonine/serine exporter family protein -
  NPA45_RS11565 - 2433577..2433987 (-) 411 WP_309215862.1 hypothetical protein -
  NPA45_RS11570 - 2434048..2435427 (-) 1380 WP_309215863.1 bacteriocin secretion accessory protein -
  NPA45_RS11575 comA 2435440..2437632 (-) 2193 WP_309215864.1 peptide cleavage/export ABC transporter Regulator
  NPA45_RS11580 - 2437927..2438082 (-) 156 WP_168163043.1 bacteriocin-like peptide, LSEI_2386 family -
  NPA45_RS11585 - 2438508..2439557 (+) 1050 WP_309215865.1 GHKL domain-containing protein -
  NPA45_RS11590 - 2439562..2440338 (+) 777 WP_309215866.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  NPA45_RS11595 - 2441214..2441627 (-) 414 WP_309215867.1 hypothetical protein -
  NPA45_RS11600 - 2441780..2441959 (-) 180 WP_309215868.1 hypothetical protein -
  NPA45_RS11605 - 2442076..2442252 (-) 177 WP_309215869.1 bacteriocin leader domain-containing protein -

Sequence

Protein


Download         Length: 730 a.a.        Molecular weight: 81429.63 Da        Isoelectric Point: 6.7314

>NTDB_id=712371 NPA45_RS11575 WP_309215864.1 2435440..2437632(-) (comA) [Lacticaseibacillus rhamnosus strain Fmb14]
MVKHTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSLAHLRELAKTNQDGTTALGIVRAAEALAFETKPVQA
AMQLFDFEDVPYPFIAHVLKRGELLHYYVVFKATRTGILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKED
KGSLFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGLLVAYLLQAVLTYGQNFLM
AVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFADANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLV
SLIAVPCYLVIVFAFQRPFDRLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLEKSFSYTKADQL
QQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEFKE
QRHLTERHLIEGPLRVQGVSFKYGFGQDVLKNINLEVPENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPV
KDINLTTLRQYIEYVPQDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAEDIANLPQQWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGKIVEQGDHATLLAQ
DGYYARLVHE

Nucleotide


Download         Length: 2193 bp        

>NTDB_id=712371 NPA45_RS11575 WP_309215864.1 2435440..2437632(-) (comA) [Lacticaseibacillus rhamnosus strain Fmb14]
ATGGTTAAACACACCCCAAAACTAGGCCAGATCACCTACTACAAACGCTTCTACACCGCACAAGTTGACGAGCGTGACTG
TGGTGTGGCTGCGTTAAACATGCTGCTTAAGTACAATGGTTCGGACTATTCGTTAGCCCACTTGCGCGAGTTAGCGAAGA
CAAATCAGGATGGCACGACTGCTTTGGGAATCGTTCGGGCTGCTGAAGCACTAGCGTTTGAGACGAAACCGGTGCAGGCG
GCTATGCAGTTGTTTGATTTTGAGGATGTGCCTTATCCGTTTATTGCCCATGTGCTGAAGCGCGGTGAATTGCTTCATTA
TTATGTTGTTTTTAAGGCAACGCGTACGGGTATTCTGATTGGCGATCCTGACCCATCAGTGCGCATGACCTGGCTTTCGC
GAGAGGTGTTTGAAAAAGAATGGTCGGGTGTGGCCATCTTTATTGCACCGGCGCCGCAGTATCAGCCGCGTAAGGAGGAC
AAAGGCAGTTTGTTTGCGTTTGTACCTATGCTGGCTAAGCAAAAAGGTATTATCGCGAACATTATTCTGGCTGCGGTATT
GATTACGGTCATTAGTATCGTTGGGTCGTATTTTTTGCAGTCTATCATTGATACGTACATCCCCAATGCCATGCGAACGA
CGATGGGGATGATTGCTAGTGGCCTTTTGGTGGCTTACTTGCTGCAAGCAGTGTTGACTTATGGCCAGAATTTTTTGATG
GCGGTGTTGGGGCAGCGGCTTGCGATTGATGTCATTTTAGGGTATGTGCGCCATTTATATGAATTGCCGATGTCTTTTTT
TTCAACTCGGCGGACCGGAGAGATTGTGTCGCGGTTTGCGGACGCGAATAAAATTATTGATGCGTTGGCGAATACGATTA
TGACGTTATTTTTGGATGTCTGGATTGTCCTAATATTAGGCATTGTTCTAGGGATCCAAAATGGGACTTTGTTTTTAGTG
TCATTGATTGCCGTGCCGTGTTACTTGGTGATTGTTTTTGCATTTCAGCGGCCGTTTGATCGGTTGAACCAAGAGACGAT
GGAAAGTAACGCAATCTTGAGTTCATCGATTATTGAAGATTTGAATGGCATTGAAACCATCAAGTCCCTGACCGGCGAAC
GAGTTAGCTATGAACGGGTTGATCGGGAATTTCTAACCTATTTGGAGAAGTCGTTTAGTTACACCAAGGCAGATCAGTTA
CAACAAGCGATTAAAGGTCTGTTGAAGCTGGCGTTGAACGTTGTGGTGTTGTGGATTGGCGCAAGTTTGGTGATTGCGAA
TCGGATGAGTTTGGGGCAGATGCTGACCTTTAATGCGTTGCTGTCATACTTTACGAATCCACTTGAAAGCATCATCAACC
TGCAGCCAAAGTTACAAATGGCGCGGGTTGCTAACAATCGTTTGAATGAGGTTTATCTGGTCGAATCGGAATTCAAAGAA
CAGCGGCACTTGACGGAGCGGCATTTAATCGAAGGCCCGTTACGCGTTCAGGGTGTCTCGTTTAAATATGGTTTTGGCCA
AGATGTGTTGAAAAACATCAACCTTGAAGTGCCGGAAAATGCTAAATATACCATTGTCGGTATGAGTGGTTCTGGTAAGT
CGACATTAGCAAAATTATTAGTTGGTTTTTACCCGGTTGATGCCGATAAAGGGACCATCACGTTTAATGGTATTCCGGTC
AAAGACATTAACCTGACAACATTACGGCAATATATTGAATATGTACCTCAGGATCCGTTTATTTTTTCGGGCACGGTGTT
GGAGAATTTGACGTTAGGTAGCCGTTCGGATGTTTCGGAACAAGACTTGACGCAGGCGTGTTTGGCTGCGGAAATTGCCG
AAGACATCGCAAACTTACCGCAGCAGTGGCAGACCAAATTGTCAGAAAGCGGCAGCATTTTATCAGGCGGTCAGAAGCAG
CGGCTGGCGATTGCACGGGCCTTGTTATCGCCGGCAAAAGTACTGATTTTTGACGAATCGACCAGCAGTCTGGATACCAT
TACAGAGCGAAAAATTGTCGATCGCTTGCTGGCAATGACGGATCGGACCATTATTTTTGTTGCCCATCGCTTAACCATTG
CGGCTAAAACCGAACAAATTGTGGTGATGGATCATGGCAAAATTGTGGAACAAGGTGACCATGCAACGTTGTTAGCCCAA
GACGGTTATTATGCGCGCTTGGTTCATGAGTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(18-152)

ABC transporter (ABC_tran)

(510-662)

ABC transporter transmembrane region (ABC_membrane)

(180-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae D39

58.042

97.945

0.568
  comA Streptococcus pneumoniae R6

58.042

97.945

0.568
  comA Streptococcus pneumoniae Rx1

58.042

97.945

0.568
  comA Streptococcus pneumoniae TIGR4

57.622

97.945

0.564
  comA Streptococcus mitis NCTC 12261

57.622

97.945

0.564
  comA Streptococcus mitis SK321

57.483

97.945

0.563
  comA Streptococcus gordonii str. Challis substr. CH1

56.328

98.493

0.555
  comA/nlmT Streptococcus mutans UA159

53.825

98.493

0.53