Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NOV99_RS02540 Genome accession   NZ_CP101844
Coordinates   505154..505876 (+) Length   240 a.a.
NCBI ID   WP_024417838.1    Uniprot ID   -
Organism   Streptococcus suis strain 2018WUSS151     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 500154..510876
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NOV99_RS02515 (NOV99_02515) - 500437..501339 (+) 903 WP_002942264.1 SPFH domain-containing protein -
  NOV99_RS02520 (NOV99_02520) - 501425..501634 (+) 210 WP_009910800.1 hypothetical protein -
  NOV99_RS02525 (NOV99_02525) - 501762..502505 (-) 744 WP_024393419.1 amino acid ABC transporter ATP-binding protein -
  NOV99_RS02530 (NOV99_02530) - 502498..504063 (-) 1566 WP_024393418.1 ABC transporter substrate-binding protein/permease -
  NOV99_RS02535 (NOV99_02535) - 504190..505026 (+) 837 WP_024417837.1 undecaprenyl-diphosphate phosphatase -
  NOV99_RS02540 (NOV99_02540) mecA 505154..505876 (+) 723 WP_024417838.1 adaptor protein MecA Regulator
  NOV99_RS02545 (NOV99_02545) - 505873..507045 (+) 1173 WP_002938168.1 glycosyltransferase family 4 protein -
  NOV99_RS02550 (NOV99_02550) sufC 507525..508298 (+) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  NOV99_RS02555 (NOV99_02555) sufD 508315..509577 (+) 1263 WP_024417839.1 Fe-S cluster assembly protein SufD -
  NOV99_RS02560 (NOV99_02560) - 509579..510805 (+) 1227 WP_002938158.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27999.60 Da        Isoelectric Point: 4.0987

>NTDB_id=712303 NOV99_RS02540 WP_024417838.1 505154..505876(+) (mecA) [Streptococcus suis strain 2018WUSS151]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIKDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=712303 NOV99_RS02540 WP_024417838.1 505154..505876(+) (mecA) [Streptococcus suis strain 2018WUSS151]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTCGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAAAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCATTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCTAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471