Detailed information NTG0712299

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: NOV99_RS00995
• Genome accession: NZ_CP101844
• Coordinates: 174494..176488 (+)
• Length: 664 a.a.
• NCBI ID: WP_004194142.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 2018WUSS151
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	176596..182992	174494..176488	flank	108

Gene organization within MGE regions

Location: 174494..182992

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NOV99_RS00995 (NOV99_00995)	stkP	174494..176488 (+)	1995	WP_004194142.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
NOV99_RS01000 (NOV99_01000)	-	176596..177885 (+)	1290	WP_002935134.1	IS4-like element ISSsu2 family transposase	-
NOV99_RS01005 (NOV99_01005)	-	178214..179415 (-)	1202	Protein_166	IS110 family transposase	-
NOV99_RS01010 (NOV99_01010)	-	179764..180450 (+)	687	WP_013730663.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
NOV99_RS01015 (NOV99_01015)	-	180483..181334 (+)	852	WP_013730662.1	amino acid ABC transporter substrate-binding protein	-
NOV99_RS01020 (NOV99_01020)	-	181790..182992 (-)	1203	WP_305880397.1	IS110-like element ISSsu7 family transposase	-

Sequence

Protein

• Length: 664 a.a.
• Molecular weight: 71560.17 Da
• Isoelectric Point: 6.7857

>NTDB_id=712299 NOV99_RS00995 WP_004194142.1 174494..176488(+) (stkP) [Streptococcus suis strain 2018WUSS151]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KSPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIATGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSRNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSTGSSTSTSTSTDSGQ

Nucleotide

• Length: 1995 bp

>NTDB_id=712299 NOV99_RS00995 WP_004194142.1 174494..176488(+) (stkP) [Streptococcus suis strain 2018WUSS151]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTTGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAATGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGGTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGGATTATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCTTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGACCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCTCAAGCCAATGTTGAAACGAAAGTACCGCATACAAATAGTTCCGCCCAAGTTTCTGCGACAGAT
AAGAGCCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGACTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCACGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTCGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAACAGGAAGTTCCACAAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-240)

• PASTA domain (PASTA) (574-638)

• PASTA domain (PASTA) (372-434)

• PASTA domain (PASTA) (507-569)

• PASTA domain (PASTA) (441-501)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	52.187	99.849	0.521
stkP	Streptococcus pneumoniae D39	52.036	99.849	0.52
stkP	Streptococcus pneumoniae R6	52.036	99.849	0.52
stkP	Streptococcus pneumoniae Rx1	51.885	99.849	0.518
stkP/pknB	Streptococcus salivarius strain HSISS4	52.479	88.102	0.462
pknB	Streptococcus mutans UA159	54.393	80.572	0.438