Detailed information NTG0071181

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: K6J69_RS03780
• Genome accession: NZ_AP018777
• Coordinates: 759983..761203 (-)
• Length: 406 a.a.
• NCBI ID: WP_110431166.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain CHBN-III-6 isolate 13H31
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 754983..766203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6J69_RS03740 (CHBNIII6_07120)	-	755875..756081 (-)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
K6J69_RS03745 (CHBNIII6_07130)	-	756155..756361 (-)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
K6J69_RS03750 (CHBNIII6_07140)	-	756447..756653 (-)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
K6J69_RS03755 (CHBNIII6_07150)	-	756739..756945 (-)	207	WP_005686717.1	heavy-metal-associated domain-containing protein	-
K6J69_RS03760 (CHBNIII6_07160)	-	757022..757399 (+)	378	WP_050848920.1	Cu(I)-responsive transcriptional regulator	-
K6J69_RS03765 (CHBNIII6_07170)	metJ	757413..757730 (-)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
K6J69_RS03770 (CHBNIII6_07180)	rho	757978..759240 (+)	1263	WP_005648966.1	transcription termination factor Rho	-
K6J69_RS03775 (CHBNIII6_07190)	pilD	759294..759986 (-)	693	WP_050848919.1	A24 family peptidase	Machinery gene
K6J69_RS03780 (CHBNIII6_07200)	pilC	759983..761203 (-)	1221	WP_110431166.1	type II secretion system F family protein	Machinery gene
K6J69_RS03785 (CHBNIII6_07210)	pilB	761200..762594 (-)	1395	WP_110431165.1	GspE/PulE family protein	Machinery gene
K6J69_RS03790 (CHBNIII6_07220)	pilA	762591..763040 (-)	450	WP_012054948.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
K6J69_RS03795 (CHBNIII6_07230)	ampD	763155..763709 (+)	555	WP_110431164.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
K6J69_RS03800 (CHBNIII6_07240)	corC	764342..765241 (+)	900	WP_005662987.1	CNNM family magnesium/cobalt transport protein CorC	-

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 46366.66 Da
• Isoelectric Point: 9.9102

>NTDB_id=71181 K6J69_RS03780 WP_110431166.1 759983..761203(-) (pilC) [Haemophilus influenzae strain CHBN-III-6 isolate 13H31]
MTKKLFYYQASNPLNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKRIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQIKKTLVNDIILDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide

• Length: 1221 bp

>NTDB_id=71181 K6J69_RS03780 WP_110431166.1 759983..761203(-) (pilC) [Haemophilus influenzae strain CHBN-III-6 isolate 13H31]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACCCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGTCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTTACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAGAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTAAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAATCAAGAAAACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCTGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-185)

• Type II secretion system (T2SS), protein F (T2SSF) (266-397)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Haemophilus influenzae Rd KW20	98.522	100	0.985
pilC	Haemophilus influenzae 86-028NP	97.291	100	0.973
pilC	Glaesserella parasuis strain SC1401	38.155	98.768	0.377