Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J64_RS03590 Genome accession   NZ_AP018775
Coordinates   702100..703317 (+) Length   405 a.a.
NCBI ID   WP_014550481.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-III-4 isolate 12H35     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 697100..708317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J64_RS03570 (CHBNIII4_06850) corC 698066..698965 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J64_RS03575 (CHBNIII4_06860) ampD 699588..700148 (-) 561 WP_014550480.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J64_RS03580 (CHBNIII4_06870) pilA 700263..700712 (+) 450 WP_011271973.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J64_RS03585 (CHBNIII4_06880) pilB 700709..702103 (+) 1395 WP_011271972.1 GspE/PulE family protein Machinery gene
  K6J64_RS03590 (CHBNIII4_06890) pilC 702100..703317 (+) 1218 WP_014550481.1 type II secretion system F family protein Machinery gene
  K6J64_RS03595 (CHBNIII4_06900) pilD 703314..704006 (+) 693 WP_014550482.1 A24 family peptidase Machinery gene
  K6J64_RS03600 (CHBNIII4_06910) rho 704060..705322 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  K6J64_RS03605 (CHBNIII4_06920) metJ 705570..705887 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J64_RS03610 (CHBNIII4_06930) cueR 705901..706287 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  K6J64_RS03615 (CHBNIII4_06940) - 706364..706570 (+) 207 WP_005666692.1 heavy-metal-associated domain-containing protein -
  K6J64_RS03620 (CHBNIII4_06950) - 706656..706862 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J64_RS03625 (CHBNIII4_06960) - 706936..707142 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J64_RS03630 (CHBNIII4_06970) - 707216..707422 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46089.34 Da        Isoelectric Point: 9.9010

>NTDB_id=71114 K6J64_RS03590 WP_014550481.1 702100..703317(+) (pilC) [Haemophilus influenzae strain CHBN-III-4 isolate 12H35]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNKWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=71114 K6J64_RS03590 WP_014550481.1 702100..703317(+) (pilC) [Haemophilus influenzae strain CHBN-III-4 isolate 12H35]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTA
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACAAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTACCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.983
  pilC Haemophilus influenzae Rd KW20

96.798

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.5

98.765

0.38

Multiple sequence alignment