Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J68_RS03605 Genome accession   NZ_AP018773
Coordinates   709768..710985 (+) Length   405 a.a.
NCBI ID   WP_005686722.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-III-2 isolate 13H39     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 704768..715985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J68_RS03585 (CHBNIII2_06910) corC 705725..706624 (-) 900 WP_011961742.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J68_RS03590 (CHBNIII2_06920) ampD 707247..707807 (-) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J68_RS03595 (CHBNIII2_06930) pilA 707922..708371 (+) 450 WP_005686726.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J68_RS03600 (CHBNIII2_06940) pilB 708368..709771 (+) 1404 WP_105197617.1 GspE/PulE family protein Machinery gene
  K6J68_RS03605 (CHBNIII2_06950) pilC 709768..710985 (+) 1218 WP_005686722.1 type II secretion system F family protein Machinery gene
  K6J68_RS03610 (CHBNIII2_06960) pilD 710982..711674 (+) 693 WP_005686720.1 A24 family peptidase Machinery gene
  K6J68_RS03615 (CHBNIII2_06970) rho 711728..712990 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  K6J68_RS03620 (CHBNIII2_06980) metJ 713238..713555 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J68_RS03625 (CHBNIII2_06990) cueR 713569..713955 (-) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  K6J68_RS03630 (CHBNIII2_07000) - 714032..714238 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J68_RS03635 (CHBNIII2_07010) - 714324..714530 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J68_RS03640 (CHBNIII2_07020) - 714616..714822 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J68_RS03645 (CHBNIII2_07030) - 714908..715114 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46122.32 Da        Isoelectric Point: 9.7232

>NTDB_id=71043 K6J68_RS03605 WP_005686722.1 709768..710985(+) (pilC) [Haemophilus influenzae strain CHBN-III-2 isolate 13H39]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRELTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQKKNQLISVTPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=71043 K6J68_RS03605 WP_005686722.1 709768..710985(+) (pilC) [Haemophilus influenzae strain CHBN-III-2 isolate 13H39]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGAGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAAAAGAAAAATCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAGGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.975
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.25

98.765

0.378

Multiple sequence alignment