Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   PFZ59_RS11285 Genome accession   NZ_CP116393
Coordinates   2215415..2217652 (-) Length   745 a.a.
NCBI ID   WP_277697115.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2210415..2222652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS11270 (PFZ59_11270) - 2212494..2213342 (-) 849 WP_277697113.1 IS630 family transposase -
  PFZ59_RS11275 (PFZ59_11275) sodA 2213570..2214175 (-) 606 WP_044768724.1 superoxide dismutase SodA -
  PFZ59_RS11280 (PFZ59_11280) holA 2214288..2215319 (-) 1032 WP_277697114.1 DNA polymerase III subunit delta -
  PFZ59_RS11285 (PFZ59_11285) comEC/celB 2215415..2217652 (-) 2238 WP_277697115.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  PFZ59_RS11290 (PFZ59_11290) comEA/celA/cilE 2217636..2218298 (-) 663 WP_208582318.1 helix-hairpin-helix domain-containing protein Machinery gene
  PFZ59_RS11295 (PFZ59_11295) - 2218365..2219111 (-) 747 WP_024385479.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  PFZ59_RS11300 (PFZ59_11300) - 2219258..2220703 (+) 1446 WP_277697116.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  PFZ59_RS11305 (PFZ59_11305) - 2220973..2222175 (-) 1203 WP_347176381.1 IS110 family transposase -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83896.64 Da        Isoelectric Point: 6.5118

>NTDB_id=709898 PFZ59_RS11285 WP_277697115.1 2215415..2217652(-) (comEC/celB) [Streptococcus suis strain SS/UPM/MY/F001]
MSRLSKLPCQPIHLAILAVAAYFVVHSFSLLTMGLLSLLLLVFGFRQGKAVFIKTLPLLALCGLFFGYQKVQWERADQSA
PEQVTTVQIIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQAYFQKLTGLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSIWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPLVKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRKKNWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HVGDVLEVANQVQIGRIYVSPGSLTVPDFVATLKEINVPVDVVAVGDRLPIFDSYLEVLYPDGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLIESYPQLPVDVLKAGHHGSKGSSYPEFLDHIGVKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=709898 PFZ59_RS11285 WP_277697115.1 2215415..2217652(-) (comEC/celB) [Streptococcus suis strain SS/UPM/MY/F001]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATCCACTTGGCCATCTTAGCAGTAGCAGCCTACTTTGTAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTCAGTTTGTTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGGCAGTTTTCATCA
AAACGCTGCCGCTTTTAGCCCTATGTGGTCTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTCACCACTGTGCAGATCATTCCAGATACCATTGAAGTCAACGGGGACAGCCTGTCCTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTGTTTTACAAATTAGCCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGCTGACAGGTCTGG
TTCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGCTATCAATCTGGCGGAGGCAGGCTTTGGTTTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGATCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAGAAAATTCTGGGCAATATGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGCTGATTCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTGATGACCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACTTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTCCTCTCACCCTTGGTCAAGATCACCTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCTGATTTGGGTTTTCGGCCTTGGATACTGGGTAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TACTTTATGATTTCCACAGGAAGAAAAACTGGCTCCTAGGACTGAGCCTAGTCCTTGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGTCGGGTCGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACATTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGCTTGGTTCTGACCCATACCGACGCTGAC
CATGTGGGCGATGTTCTGGAAGTGGCGAATCAGGTCCAGATTGGTCGGATTTACGTGTCGCCAGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATCAATGTCCCTGTTGATGTGGTGGCGGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAAGTTCTCTATCCAGACGGGACGGGTGACGGTGGCAATAATGACTCTGTTGTTCTTTACGGTCGTTTGCTG
GAAACCAATTTTCTCTTTACAGGGGATTTGGAGCAGGGGGAGCTGGATTTGATAGAAAGCTATCCGCAGCTACCTGTTGA
TGTCCTCAAAGCTGGTCACCATGGCTCCAAAGGGTCCTCCTATCCTGAGTTTCTAGACCATATCGGAGTCAAGATTGCCC
TGGTATCAGCAGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGAAATATCCAA
GTCTATCGCACCGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAGTAA

Domains

Predicted by InterProScan.

Domain of unknown function (DUF4131) (DUF4131)

(28-175)

Competence protein (Competence)

(215-460)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.105

99.732

0.54
  comEC/celB Streptococcus mitis NCTC 12261

52.901

99.463

0.526
  comEC/celB Streptococcus pneumoniae TIGR4

52.022

99.597

0.518
  comEC/celB Streptococcus pneumoniae Rx1

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae D39

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae R6

51.752

99.597

0.515
  comEC Lactococcus lactis subsp. cremoris KW2

48.732

100

0.49