Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NMJ60_RS06725 Genome accession   NZ_CP101314
Coordinates   1337615..1338487 (+) Length   290 a.a.
NCBI ID   WP_000593194.1    Uniprot ID   A0A9P3DKN4
Organism   Staphylococcus aureus strain #492     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1332615..1343487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMJ60_RS06705 sucC 1332729..1333895 (+) 1167 WP_233231695.1 ADP-forming succinate--CoA ligase subunit beta -
  NMJ60_RS06710 sucD 1333917..1334825 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  NMJ60_RS06715 - 1335052..1336170 (+) 1119 WP_001041666.1 LysM peptidoglycan-binding domain-containing protein -
  NMJ60_RS06720 fmhC 1336198..1337442 (+) 1245 WP_000672869.1 FemA/FemB family glycyltransferase FmhC -
  NMJ60_RS06725 dprA 1337615..1338487 (+) 873 WP_000593194.1 DNA-processing protein DprA Machinery gene
  NMJ60_RS06730 topA 1338661..1340736 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  NMJ60_RS06735 trmFO 1340892..1342199 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33541.01 Da        Isoelectric Point: 9.5093

>NTDB_id=709633 NMJ60_RS06725 WP_000593194.1 1337615..1338487(+) (dprA) [Staphylococcus aureus strain #492]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVLLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=709633 NMJ60_RS06725 WP_000593194.1 1337615..1338487(+) (dprA) [Staphylococcus aureus strain #492]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCTTTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

100

100

1
  dprA Staphylococcus aureus MW2

99.655

100

0.997
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae D39

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae R6

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus mitis SK321

37.456

97.586

0.366