Detailed information NTG0070904

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: H7680_RS00755
• Genome accession: NZ_AP023394
• Coordinates: 123137..123577 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 159
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118137..128577

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7680_RS00725 (SDSE159_00960)	-	119818..120183 (+)	366	WP_003055257.1	DUF1033 family protein	-
H7680_RS00730 (SDSE159_00970)	comGA/cglA	120264..121205 (+)	942	WP_014611930.1	competence type IV pilus ATPase ComGA	Machinery gene
H7680_RS00735 (SDSE159_00980)	comGB	121141..122172 (+)	1032	WP_015057201.1	competence type IV pilus assembly protein ComGB	Machinery gene
H7680_RS00740 (SDSE159_00990)	comGC	122174..122500 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
H7680_RS00745	comGD	122475..122903 (+)	429	WP_014611932.1	competence type IV pilus minor pilin ComGD	Machinery gene
H7680_RS00750 (SDSE159_01000)	comGE	122911..123156 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
H7680_RS00755 (SDSE159_01010)	comGF	123137..123577 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
H7680_RS00760 (SDSE159_01020)	comGG	123600..123929 (+)	330	WP_231117501.1	competence type IV pilus minor pilin ComGG	-
H7680_RS00765 (SDSE159_01030)	comGH	123992..124945 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
H7680_RS00770 (SDSE159_01040)	-	125004..126200 (+)	1197	WP_003058485.1	acetate kinase	-
H7680_RS00775 (SDSE159_01050)	-	126506..126712 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
H7680_RS00780 (SDSE159_01060)	-	126815..127495 (+)	681	WP_012766451.1	type II CAAX endopeptidase family protein	-
H7680_RS00785 (SDSE159_01070)	-	127513..127950 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=70904 H7680_RS00755 WP_003061780.1 123137..123577(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=70904 H7680_RS00755 WP_003061780.1 123137..123577(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAATAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411