Detailed information NTG0070903

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: K6J61_RS03585
• Genome accession: NZ_AP018769
• Coordinates: 714600..715820 (+)
• Length: 406 a.a.
• NCBI ID: WP_048942289.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain CHBN-II-6 isolate 12H01
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 709600..720820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6J61_RS03565 (CHBNII6_06790)	corC	710563..711462 (-)	900	WP_005656283.1	CNNM family magnesium/cobalt transport protein CorC	-
K6J61_RS03570 (CHBNII6_06800)	ampD	712084..712647 (-)	564	WP_048942277.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
K6J61_RS03575 (CHBNII6_06810)	pilA	712763..713212 (+)	450	WP_048942287.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
K6J61_RS03580 (CHBNII6_06820)	pilB	713209..714603 (+)	1395	WP_110459385.1	GspE/PulE family protein	Machinery gene
K6J61_RS03585 (CHBNII6_06830)	pilC	714600..715820 (+)	1221	WP_048942289.1	type II secretion system F family protein	Machinery gene
K6J61_RS03590 (CHBNII6_06840)	pilD	715817..716509 (+)	693	WP_048942290.1	A24 family peptidase	Machinery gene
K6J61_RS03595 (CHBNII6_06850)	rho	716563..717825 (-)	1263	WP_005648966.1	transcription termination factor Rho	-
K6J61_RS03600 (CHBNII6_06860)	metJ	718073..718390 (+)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
K6J61_RS03605 (CHBNII6_06870)	cueR	718404..718790 (-)	387	WP_005648963.1	Cu(I)-responsive transcriptional regulator	-
K6J61_RS03610 (CHBNII6_06880)	-	718867..719073 (+)	207	WP_005666692.1	heavy-metal-associated domain-containing protein	-
K6J61_RS03615 (CHBNII6_06890)	-	719159..719365 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
K6J61_RS03620 (CHBNII6_06900)	-	719439..719645 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
K6J61_RS03625 (CHBNII6_06910)	-	719719..719925 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 46305.62 Da
• Isoelectric Point: 9.9010

>NTDB_id=70903 K6J61_RS03585 WP_048942289.1 714600..715820(+) (pilC) [Haemophilus influenzae strain CHBN-II-6 isolate 12H01]
MTKKLFYYQASNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTHIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQIKKTLVNDIILDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide

• Length: 1221 bp

>NTDB_id=70903 K6J61_RS03585 WP_048942289.1 714600..715820(+) (pilC) [Haemophilus influenzae strain CHBN-II-6 isolate 12H01]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACATTGCTACAATCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCACATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCGATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTGTTAGGAATTTCACTATTACTAACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCGACAATCACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAATCAAGAAAACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAACATATTGCGGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCAGTTATTCAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-185)

• Type II secretion system (T2SS), protein F (T2SSF) (266-397)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Haemophilus influenzae Rd KW20	98.522	100	0.985
pilC	Haemophilus influenzae 86-028NP	97.783	100	0.978
pilC	Glaesserella parasuis strain SC1401	38.155	98.768	0.377