Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   H7680_RS00745 Genome accession   NZ_AP023394
Coordinates   122475..122903 (+) Length   142 a.a.
NCBI ID   WP_014611932.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain 159     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117475..127903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7680_RS00725 (SDSE159_00960) - 119818..120183 (+) 366 WP_003055257.1 DUF1033 family protein -
  H7680_RS00730 (SDSE159_00970) comGA/cglA 120264..121205 (+) 942 WP_014611930.1 competence type IV pilus ATPase ComGA Machinery gene
  H7680_RS00735 (SDSE159_00980) comGB 121141..122172 (+) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7680_RS00740 (SDSE159_00990) comGC 122174..122500 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  H7680_RS00745 comGD 122475..122903 (+) 429 WP_014611932.1 competence type IV pilus minor pilin ComGD Machinery gene
  H7680_RS00750 (SDSE159_01000) comGE 122911..123156 (+) 246 WP_003058569.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7680_RS00755 (SDSE159_01010) comGF 123137..123577 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7680_RS00760 (SDSE159_01020) comGG 123600..123929 (+) 330 WP_231117501.1 competence type IV pilus minor pilin ComGG -
  H7680_RS00765 (SDSE159_01030) comGH 123992..124945 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  H7680_RS00770 (SDSE159_01040) - 125004..126200 (+) 1197 WP_003058485.1 acetate kinase -
  H7680_RS00775 (SDSE159_01050) - 126506..126712 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -
  H7680_RS00780 (SDSE159_01060) - 126815..127495 (+) 681 WP_012766451.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16410.89 Da        Isoelectric Point: 9.9660

>NTDB_id=70902 H7680_RS00745 WP_014611932.1 122475..122903(+) (comGD) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
MRLKNCNLKAFTLLESLLTLSVTSFIVLGLSVPVTSSYRRVQEQLFFTRFEHFYRHQQKLAILEHDQRVLTISSKQMLAA
EESLTIPDLIRVKNSQQLVIDQMGGNHSLAKIIFETTDQRVTYQFYLGSGNYQKTSQSLHRS

Nucleotide


Download         Length: 429 bp        

>NTDB_id=70902 H7680_RS00745 WP_014611932.1 122475..122903(+) (comGD) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
ATGAGACTCAAAAACTGCAACCTTAAAGCTTTCACATTGCTTGAAAGCTTATTAACGCTATCAGTAACAAGTTTTATTGT
CTTGGGGTTATCTGTGCCTGTGACAAGTAGTTATCGAAGGGTTCAGGAACAGCTTTTTTTCACTCGTTTTGAGCACTTTT
ATCGTCACCAACAAAAGTTGGCTATTTTGGAACATGATCAACGAGTTTTGACAATTTCTTCGAAACAAATGCTAGCGGCA
GAGGAGTCGTTAACAATACCTGACTTGATAAGGGTTAAGAATAGCCAGCAATTGGTTATTGATCAAATGGGAGGAAATCA
TTCTTTAGCAAAGATAATATTCGAGACGACTGATCAACGGGTAACTTATCAATTTTATCTAGGGAGTGGAAATTATCAAA
AAACAAGTCAAAGCTTACATCGCTCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus gordonii str. Challis substr. CH1

43.382

95.775

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

38.235

95.775

0.366

Multiple sequence alignment