Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGCSD_RS02165 Genome accession   NZ_AP018726
Coordinates   405666..406427 (+) Length   253 a.a.
NCBI ID   WP_129555296.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain Kdys0611     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 400666..411427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGCSD_RS02150 (FGCSD_0368) - 401619..402614 (+) 996 WP_129555294.1 IS30 family transposase -
  FGCSD_RS02155 (FGCSD_0369) - 402694..404616 (+) 1923 WP_129555295.1 DUF2207 domain-containing protein -
  FGCSD_RS02160 (FGCSD_0370) - 404683..405522 (+) 840 WP_015057324.1 undecaprenyl-diphosphate phosphatase -
  FGCSD_RS02165 (FGCSD_0371) mecA 405666..406427 (+) 762 WP_129555296.1 adaptor protein MecA Regulator
  FGCSD_RS02170 (FGCSD_0372) - 406434..407603 (+) 1170 WP_115246691.1 MraY family glycosyltransferase -
  FGCSD_RS02175 (FGCSD_0373) sufC 407716..408486 (+) 771 WP_003061584.1 Fe-S cluster assembly ATPase SufC -
  FGCSD_RS02180 (FGCSD_0374) sufD 408583..409845 (+) 1263 WP_129555297.1 Fe-S cluster assembly protein SufD -
  FGCSD_RS02185 (FGCSD_0375) - 409876..411102 (+) 1227 WP_048327758.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29143.74 Da        Isoelectric Point: 4.0570

>NTDB_id=70567 FGCSD_RS02165 WP_129555296.1 405666..406427(+) (mecA) [Streptococcus dysgalactiae strain Kdys0611]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVDQEPEPLDYVH
YVLDFATLSEAVTFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=70567 FGCSD_RS02165 WP_129555296.1 405666..406427(+) (mecA) [Streptococcus dysgalactiae strain Kdys0611]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGATCTACCAGATAATT
TCAAAGATAGTGGCATGCTTAGTTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAGGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACTGCTGAGGAAGTGGATCAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCACTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTAATTCTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.4

98.814

0.636
  mecA Streptococcus thermophilus LMD-9

57.831

98.419

0.569
  mecA Streptococcus thermophilus LMG 18311

57.028

98.419

0.561
  mecA Streptococcus pneumoniae Rx1

47.451

100

0.478
  mecA Streptococcus pneumoniae D39

47.451

100

0.478
  mecA Streptococcus pneumoniae R6

47.451

100

0.478
  mecA Streptococcus pneumoniae TIGR4

47.451

100

0.478

Multiple sequence alignment